Alaa Ahmed

Alaa A. Ahmed

Associate Professor
Integrative Physiology
Research Interests: Biomechanical and sensorimotor processes underlying human movement control and decision-making in uncertain or unstable environments. Neuromechanics of postural control, loss of balance detection, and falls in young and older adults. Investigating the stimulus for muscle hypertrophy using multi-scale biomechanical models of lengthening contractions during progressive resistance training.
Tanya Alderete

Tanya L. Alderete

Assistant Professor
Integrative Physiology
Research Interests: Obesity, Type 2 Diabetes, environmental exposures, and the microbiome.
William Byrnes

William Byrnes

Associate Professor
Integrative Physiology
Research Interests: The acute and chronic physiological adaptations to exercise-induced muscle injury, to resistance exercise, and to exercise in hyper/hypobaric environments.
Chris Depner

Christopher Depner

Assistant Research Professor
Integrative Physiology
Research Interests: Mitigate the risk and burden of chronic metabolic disease at the individual level and for society as a whole. Identify the mechanisms underlying increased risk of obesity, diabetes, and other metabolic diseases associated with sleep loss and circadian disruption. Develop personalized medicine based countermeasures that integrate nutrition, and sleep and circadian health to prevent and treat metabolic disease.
Chris DeSouza

Chris DeSouza

Professor
Integrative Physiology
Research Interests: Effects of aging, cardiovascular and metabolic risk factors, and regular physical activity on nitric oxide bioavailability and vascular endothelial function.
Marissa Ehringer

Marissa Ehringer

Associate Professor
Integrative Physiology • Institute for Behavioral Genetics
Research Interests: Identification of genetic mechanisms that contribute to alcohol, tobacco, and substance use. Application of genomics and bioinformatics to the study of behavior genetics.
Roger Enoka

Roger Enoka

Professor
Integrative Physiology
Neuromuscular determinants of motor function (movement) in health and disease.
Monika Fleshner

Monika Fleshner

Professor
Integrative Physiology
Research Interests: Understanding 1) the impact of acute and chronic stressor exposure (mental or physical) on behavior, neural, hormonal and immunological function; 2) how such systems interact to affect the whole organism; and 3) the mechanisms of increased stress resistance and stress resilience produced by exercise.
Todd T. Gleeson

Todd T. Gleeson

Professor
Integrative Physiology
Research Interests: Comparative physiology of exercise; lactate and glycogen metabolism in amphibians, reptiles, and mammals; and recovery metabolism.
Alena Grabowski

Alena Grabowski

Assistant Professor
Integrative Physiology
Research Interests: The interaction of physiology and biomechanics during human locomotion; specifically how the implementation of assistive mechanical devices, such as prostheses and exoskeletons, influence walking, running, hopping, and sprinting.
Charles Hoeffer

Charles Hoeffer

Assistant Professor
Integrative Physiology • Institute for Behavioral Genetics
Research Interests: The regulation of protein synthesis in synaptic plasticity, memory and neurological disorders. Regulators of phosphatase function in Down syndrome and schizophrenia. Aging, stress, and neurodegeneration.
Tom Johnson

Thomas E. Johnson

Professor
Integrative Physiology • Institute for Behavioral Genetics
Research Interests: The study of aging using the mouse and the worm Caenorhabditis elegans as models. Mouse model of fetal alcohol syndrome. Molecular Behavioral Genetics.
Monique LeBourgeois

Monique K. LeBourgeois

Associate Professor
Integrative Physiology
Research Interests: Early developmental changes in sleep and circadian physiology. The health, behavioral, and developmental consequences of challenging the sleep and circadian systems.
Chris Link

Christopher D. Link

Associate Professor
Integrative Physiology • Institute for Behavioral Genetics
The long-term goal of our research is to understand the cellular and molecular basis of age-associated neurodegenerative diseases, such as Alzheimer's disease (AD) and Amyotrophic Lateral Sclerosis (ALS). The major focus of our studies has been the identification of the cellular and molecular mechanisms by which specific proteins central to these diseases (e.g., the beta amyloid peptide in AD and TDP-43 in ALS) induce pathology. Our primary approach has been to develop transgenic C. elegans strains that express these human proteins, often resulting in abnormal phenotypes that can be the basis of classic genetic screens. The overall rationale for this approach is that invertebrate models allow facile "pilot" studies that are time-consuming, difficult, or impossible in other systems. We complement the C. elegans studies using mammalian cell culture and bioinformatic analysis of mouse and human deep sequencing data.
Christopher Lowry

Christopher A. Lowry

Associate Professor
Integrative Physiology
Research Interests: The neural mechanisms underlying emotional behavior and the stress-induced control of physiology and emotional behavior.
Robert Mazzeo

Robert S. Mazzeo

Associate Professor
Integrative Physiology
Research Interests: Neuroendocrine and biochemical adaptations associated with acute and chronic exercise, exercise immunology, high-altitude physiology, and aging.
Matt McQueen

Matthew B. McQueen

Associate Professor
Integrative Physiology • Institute for Behavioral Genetics
Research Interests: Translational research - translating scientific discoveries into population health impact presents many unique challenges necessitating a multi-disciplinary approach that includes the study of genetic, physiological, behavioral, and environmental factors. As an epidemiologist and applied biostatistician, Professor McQueen's research objectives are focused on the development and application of epidemiological and biostatistical methods to advance our understanding of human disease from genes to populations. Toward that end, he has embraced highly integrative and collaborative research that approaches translational research in a comprehensive manner.
Russ Moore

Russell L. Moore

Professor • Executive Vice Chancellor • Provost
Integrative Physiology
Research Interests: Identify and understand cellular mechanisms that underlie the physiological (exercise training) and pathological (heart failure, advanced aging) alterations in cardiac contractile function. We are currently conducting work to understand the cellular basis for exercise-induced protection of the heart against ischemia-reperfusion injury, and on the influences of diet and exercise on cardiac energy metabolism and the development of heart failure in the SHHF rat model.
Mark Opp

Mark R. Opp

Professor • Chair
Integrative Physiology
Research Interests: To determine how chronic insufficient sleep induces inflammation and contributes to inflammatory diseases, including pain and traumatic brain injury.
Doug Seals, February 2019

Douglas R. Seals

Professor • CU Distinguished Professor
Integrative Physiology
Research Interests: Cardiovascular aging, particularly the changes in systolic blood pressure, large artery stiffness and vascular endothelial function that occur with physiological and pathophysiological aging. Biological and lifestyle factors that influence cardiovascular aging. The integrative (molecular to systemic) mechanisms that mediate cardiovascular aging and its modulation by biological and lifestyle factors. Interventions to improve adverse physiological changes with aging, including cardiovascular dysfunction, reductions in motor performance and impairments in cognitive function.
Jerry Stitzel

Jerry A. Stitzel

Associate Professor
Integrative Physiology • Institute for Behavioral Genetics
Research Interests: The use of genetic strategies to identify the underlying biological bases for the behavioral and physiological actions of drugs of abuse with special emphasis on nicotine.
Pei Tsai

Pei-San Tsai

Professor
Integrative Physiology
Research Interests: Reproductive endocrinology of vertebrates and invertebrates. Specific research foci include the development of a population of neuroendocrine neurons critical for vertebrate reproduction, functional and structural evolution of reproductive neurohormones, and how sex steroids regulate hypothalamic, pituitary, and gonadal functions.
Celine Vetter

Céline Vetter

Assistant Professor
Integrative Physiology
Research Interests: Chronic disease epidemiology; cardiometabolic health (including type 2 diabetes); circadian rhythms and sleep disruption; shift work, work hours, and occupational health.
Ken Wright

Kenneth P. Wright Jr.

Professor
Integrative Physiology
Research Interests: Health and safety consequences of insufficient sleep and circadian misalignment. Development of countermeasures and treatments for sleep and circadian disruption to improve public health and safety.