Our research focuses on computational multiscale multiphysics materials modeling for simulating inelastic deformation and failure in heterogeneous porous media, including saturated and partially saturated soils and rock, unbonded particulate materials (e.g., sand, gravel, metallic powders), bonded particulate materials (e.g., sandstone, asphalt, concrete, explosive materials), soft biological tissues (e.g., ocular lens tissue, lung parenchyma, vertebral disk), and thin deformable porous materials and membranes, for instance. Scales of interest range from the microstructural/ultrastructural to the continuum. Accounting for microstructural features and response at the pore/particle/grain scale is critical to understanding and modeling predictively a material's inelastic deformation and transition to failure at the continuum scale (engineering scale of interest). Accounting for histological features and response at the cellular/extracellular matrix (ECM) scale likewise is critical to understanding and modeling predictively a biological tissue's range of response under physiological and surgical influences as well as those encountered in the presence of prosthetic materials.