Representative Publications from the Mittal Lab and Collaborators

note: * indicates the first author was a graduate student or postdoctoral student who worked under my direct mentorship

*Dean, D., Orr, J.M, Bernard, J., Gupta, T., Pelletier-Baldelli, A., Carol, E., Mittal, V.A. (in press) Hippocampal shape abnormalities predict symptom progression and impaired tolerance to stress in youth at ultra high risk for psychosis, Schizophrenia Bulletin.

*Carol, E., Mittal, V.A., (in press). Normative adolescent experiences may confound assessment of positive symptoms in youth at ultra-high risk for psychosis.Schizophrenia Research.

*Bernard, J., Mittal, V.A. (in press). Updating the research domain criteria: the utility of a motor dimension. Psychological Medicine.

*Hagerty, S.L., YorkWilliams, S.L., Mittal, V.A. Hutchison, K. (under review) Cannabis Connundrum: thinking outside the THC box. Journal of Clinical Pharmacology.

*Carol, E., Mittal, V.A. (2015). Negative self-concept is associated with elevated resting cortisol and putative familial environment in youth at ultra high-risk for psychosis.Psychoneuroendocrinology, 57, 26-36.

*Lunsford-Avery, J., Gupta, T., LeBourgeos, M., Mittal, V.A. (in press). Sleep actigraphy indicates poorer sleep efficiency in youth at-risk for psychotic disorders.Schizophrenia Research.

Thompson, E., Millman, Z., Okuzawa, N., Mittal, V.A., DeVylder, J., Skadberg, T., Reeves, G., & Schiffman, J. (in press). Evidence-Based Early Interventions for Individuals at clinical high risk for psychosis: a review of treatment components.Journal of Nervous and Mental Disease.

*Bernard, J.A., Orr, J., & Mittal, V.A., (in press) Hippocampal-thalamic tract development in the psychosis prodrome: A multi-time point probabilistic tractography approach.NPJ Schizophrenia.

Thompson, L., Kline, E., Ellman, L. Mittal, V.A., Schiffman, J., (2015). Emotional and Behavioral symptomatology reported by help-seeking youth at clinical high-risk for psychosis. Schizophrenia Research, 162, 29-85.

*Dean D., Bernard, J., Orr, J. Pelletier, A., Carol, E., Gupta, T. Earls, H., Mittal, V.A. (in press) Increased postural sway predicts negative symptom progression in ultra high-risk for psychosis. Schizophrenia Research.

Mittal, V.A., Dean, D., Mittal, J., Saks, E. (in press). Is disclosing and attenuated psychosis syndrome diagnosis ultimately helpful or harmful? Bioethics.

Dean, D.J. & Mittal, V.A., Spontaneous Parkinsonisms and striatal impairment in neuroleptic free youth at ultra high risk for psychosis (2015), NPJ Schizophrenia, 1, DOI:10.1038/NPJSCHZ.2014.6

*Bernard, J.A., Leopold, D., Calhoun, V., Mittal, V.A. (2015) Regional Cerebellar Volume and Cognitive Function From Adolescence to Late Middle Age. Human Brain Mapping, 36:1102-1120, doi: 10.1002/hbm.22690

Schiffman, J, Mittal, V.A., Kline, E., Michelsen, N., Ekstrom, M., Mortensen, E., Mednick, S., Sorenson, H (2015). Childhood dyspraxia predictive of adult-onset schizophrenia spectrum disorder, Development and Psychopathology, doi:10.1017/S0954579414001436

*Bernard, J., & Mittal, V.A. (in press). Dysfunctional activation of the cerebellum in schizophrenia: A functional neuroimaging meta-analysis. Clinical Psychological Science, doi: 10.1177/2167702614542463

*Gupta, T., Mittal, V.A. (2014) Nicotine is associated with elevated processing speed and spatial working memory in youth at ultra high-risk for psychosis. Psychiatry Research, 15;220(1-2):687-; doi: 10.1016/j.psychres.2014.07.085.

*Bernard, J. & Mittal, V.A. (2014). Cerebellar Motor Dysfunction In Schizophrenia and Psychosis Risk: the Importance of Regional Cerebellar Analysis Approaches.Frontiers in Psychiatry, 5:160, doi: 10.3389/fpsyt.2014.00160

*Carol, E., & Mittal, V.A. (2014). Self-Reported Cannabis Use is Inconsistent with the Results From Drug-Screening in Youth at Ultra High-Risk for Psychosis,Schizophrenia Research, 157(1-3): 317-318 doi: 10.1016/j.schres.2014.05.032. [Epub ahead of print]

*Millman, Z, Goss., J., Schiffman, J., Gupta., T., Mittal, V.A. (2014). Mismatch and Lexical Retrieval Gestures are Associated with Visual Information Processing, Verbal Production, and Symptomatology in Youth at High Risk for Psychosis. Schizophrenia Research, 158(1-3): 64-68. doi: 10.1016/j.schres.2014.06.007.

*Bernard, J., & Mittal, V.A. (2014). Dysfunctional activation of the cerebellum in schizophrenia: A functional neuroimaging meta-analysis. Clinical Psychological Science, 5:160, doi: 10.3389/fpsyt.2014.00160

Schott, M.E., Cornier, M.A., Mittal,V.A., Pryor, T.L., Orr, J., Brown, M.S., Frank, G.K.W. (2015). Orbitofrontal cortex and brain reward response in obesity. International Journal of Obesity, 39(2):214-221, doi: 10.1038/ijo.2014.121.

Mittal, V.A., Dean, D.J., Bernard, J.A., Orr, JM., Pelletier, A., Carol, E., Gupta, T., Turner, J., Leopold, D., Robustelli, B., Millman, Z. (2014) Neurological Signs predict cerebellar-thalamic tract development and negative symptoms in adolescents at high risk for psychosis: a longitudinal perspective. Schizophrenia Bulletin, 40(6) 1204-1215. doi:10.1093/schbul/sbt199

*Bernard, J. Dean, D., Kent, J., Pelletier, A.L., Gupta, T., Mittal, V.A. (in press). Cerebellar Networks in Individuals at Ultra High-Risk of Psychosis: Impact on Postural Sway and Symptom Severity. Human Brain Mapping. 35(8), 4064-4078. doi: 10.1002/hbm.22458. [Epub ahead of print]

Mittal, V.A., Pelletier, A.L., Kestler, L. Bollina, Hochman, K., & Walker, E.F. (in press). Schizophrenia. In J.E. Maddox & B.A. Winstead (Eds.) Psychopathology: Foundations for a contemporary understanding (4th edition) Routledge: New York).

*Dean, D.J., Bernard, J.A., Orr, J., Pelletier, A.L., Gupta, T., Mittal, V. (2014). Cerebellar morphology and procedural learning impairment in youth at ultra high-risk of psychosis, Clinical Psychological Science. 2(2)152-164

*Orr, J, Turner, J., Mittal, V.A. (2014). Widespread brain dysconnectivity associated with psychotic-like experiences in the general population. Neuroimage:Clinical (4) 343-351.

*Pelletier, A.L., Dean, D.J., Lunsford-Avery, Smith, A.K., Orr., J., Gupta, T., Millman, Z.,Mittal, V.A. (2014). Orbitofrontal cortex volume and intrinsic religiosity in non-clinical psychosis. Psychiatry Research, Neuroimage 22(3), 124-130.

*Wu, SS., Mittal, V.A., Pennington B Willcutt, E.G. (2014). Mathematics achievement scores highlight psychosis risk in school-aged children. Schizophrenia Research,156, 133-134.

Mittal, VA, Orr, J. Turner, J. Pelletier, A., Dean, D., Lunsford-Avery, J. Gupta, T. (2013). Striatal abnormalities and Spontaneous Dyskinetic Movements in Non-Clinical Psychosis. Schizophrenia Research.151 (1-3) 141-147. doi: 10.1016/j.schres.2013.10.003

*Lunsford-Avery, J.R., Orr, J.M., Gupta, T., Pelletier, A.L., Dean, D.J Bernard, J., Smith, A., Bernard, J., Millman, Z., Mittal, V.A. (2013). Sleep Dysfunction and Thalamic Abnormalities in Adolescents at Ultra High-Risk for Psychosis. Schizophrenia Research, 151(1-3):148-53. doi: 10.1016/j.schres.2013.09.015.

Mittal, V.A., Gupta, T., Orr, J.M. Pelletier, A.L., Dean, D.J., Lunsford-Avery, J. Smith, A., Robustelli, B.R., Leopold, D.R., Millman, Z. (2013). Physical activity level and medial temporal health in youth at ultra high-risk for psychosis. Journal of Abnormal Psychology, 122(4), 1101-1110.

Frank, G., Schott, M, Hagman J., Mittal, V.A. (2013). Taste Reward circuitry related brain structures characterize ill and recovered anorexia, but also bulimia nervosa.American Journal of Psychiatry, 10(170):1152-1160. doi: 10.1176/appi.ajp.2013.12101294

*Dean, D., Caliguiri, M., Tuelings, H., & Mittal, V.A. (2013). Handwriting Analysis Indicates Spontaneous Dyskinesias in Adolescents at high-risk for schizophrenia.JoVE, 81 e50852, doi:10.3791/50852

*Dean, D.J. & Mittal, V.A. (2013). Tinnitus and symptoms in the prodrome. Schizophrenia Research, 147: 410-411 doi:10.1016/j.schres.2013.04.033.

*Lunsford-Avery, J. & Mittal, V.A. (2013). Sleep dysfunction prior to the onset of schizophrenia: a review and neurodevelopmental diathesis-stress conceptualization.Clinical Psychology: Science and Practice, 20 (3): 291-320 DOI: 10.1111/cpsp.12041.

Mittal, V.A., Dean, D., & Pelletier, A. (2013). Internet addiction, Reality Substitution, and Longitudinal Changes in Psychotic-like Experiences in Young Adults. Early Intervention in Psychiatry, 7(3) 261-9, DOI: 10.1111/j.1751-7893.2012.00390.x

Frank, G., Schott, M., Haggman, J. Mittal, V (2013). Reply to Keating and Rossell.American Journal of Psychiatry, 170(11), 1367.

Mittal, V.A., Orr, J.M. Pelletier, A.L., Dean, D.J., Lunsford-Avery, J. Smith, A. (2013). Hypothalamic-Pituitary-Adrenal Axis Dysfunction and Symptoms of Non-Clinical Psychosis. Psychiatry Research, 206(2-3):315-317

*Pelletier, A. Mittal, V.A. (2013). Negative symptom measurement in individuals at-risk for psychosis. Psychiatry Research, 205(1-2):181-182

*Pelletier, A. Dean, D. Lunsford-Avery, J.L., Orr, J., Gupta, T., Mittal, V.A. (2013).Facial emotion recognition deficits are associated with broader social/role dysfunction in non-clinical psychosis. Schizophrenia Research 143, 70-73

*Smith, A.K., & Mittal., V.A. (2013). Delusions of Body Image in the Prodrome.Schizophrenia Research, 146(1-3):366-367

Trottman, H., Mittal, V. A., Tessner, K. D., & Walker, E. F., (2013). Schizophrenia and the Psychotic spectrum. In Craighead, EW, Miklowitz, DJ, & Craighead, LW (Eds.),Psychopathology: History, Diagnosis, and empirical foundations (3rd Edition). John Wiley & Sons

Golembo-Smith, S, Walder, D, Daly, M., Mittal, V.A., Kline, E. Reeves, G., Shiffman, J (2012). The presentation of dermatoglyphic abnormalities in schizophrenia: a meta-analytic review. Schizophrenia Research 142(1-3) 1-11.

Kestler, L. Bollini, A., Hochman, K., Mittal, V. A., Walker, E. F., (2012). Schizophrenia. In J. E. Maddox & B. A. Winstead (Eds.) Psychopathology: Foundations for a Contemporary Understanding (3rd edition). Routledge: New York

Mittal, V.A., Smollen, A., Dean, D.J. Pelletier, A. Avery, J., Smith, A. (2012) BDNF val66met and spontaneous dyskinesia in non-clinical psychosis. Schizophrenia Research. DOI 10.1016/j.schres.2012.06.018

Mittal, V.A., Dean, D., & Pelletier, A. (2012). Dermatoglyphic asymmetries and fronto-striatal dysfunction in young-adults reporting non-clinical psychosis. Acta Psychiatrica Scandinavica. DOI: 10.1111/j.1600-0447.2012.01869.x

*Pelletier, A. & Mittal, V.A. (2012). An Autism Dimension for Schizophrenia in the Next Diagnostic and Statistical Manual, Schizophrenia Research. 137(1-3) 269-270.

Mittal, V.A., Dean, D., Pelletier, A., Caligiuri, M., (2011). Associations between instrumentally gauged movement abnormalities and attenuated psychotic symptoms in healthy young adults. Schizophrenia Research, 132, 194-196.

Mittal, V.A. & Walker, V. A. (2011). Dyskinesias, tics, and psychosis in the next Diagnostic and Statistical Manuel of Mental Disorders. Psychiatry Research, 189, 158-159.

Mittal, V.A., Jalbrzikowski M, Bearden, C.E., Daley M., Roman C., Cannon T.D. (2011). Abnormal movements and the longitudinal course of role and social functioning in adolescents at high-risk for psychosis. Schizophrenia Research. 130 (1 -3), 164-169.

Tessner, K. D., Mittal, V.A., & Walker, E.F. (2011). Longitudinal study of stressful life events and daily stressors among adolescents with schizotypal personality disorder,Schizophrenia Bulletin, 37(2), 432-441.

Mittal, V.A., Cannon, T.D., Bearden, C.E., (2011). Reply to De Nadai et al, American Journal of Psychiatry. 168 (5) 550-551.

Mittal, V.A., & Walker, E. F. (2011). Minor physical anomalies and hippocampal system vulnerability in youth at high clinical risk: converging evidence from neurocognitive, endocrine, and symptom profiles. Schizophrenia Research. 129, 116-121.

Karlsgodt, K. Ellman, LE. Sun, F., Mittal, V.A., Cannon TD. (2011). Is the neural developmental model of schizophrenia still alive? In Schizophrenia, The Final Frontier: A Festschrift-Tribute for Robin Murray. Edited by David, A., Kapur, S., & McGuffin, P. London: Maudsley Publication by Routledge-Taylor Francis.

Mittal, V.A., Daley, M., Shiode, M.F., Bearden, C.E., O'Neill, J., & Cannon, T.D. (2010). Striatal volumes and dyskinetic movements in youth at high-risk for psychosis.Schizophrenia Research, 123(1), 68-70.

Mittal, V.A., & Walker E.F. (2010). Movement Abnormalities and Schizophrenia in DSM V. Psychological Medicine, 40(9)1581-1583.

Mittal, V. A., Karlsgodt, K. H., Zinberg, J., Cannon, T. D. & Bearden, C. E., (2010). Identification and Treatment of a Pineal Gland Tumor in an Adolescent with Prodromal Psychotic Symptoms. American Journal of Psychiatry, 167(9), 1033-1037.

Mittal, V. A., Walker, E. F., Walder, D., Trottman, H., Bearden, C. E., Daley, M. Simone, T. & Cannon, T. D. (2010). Markers of basal ganglia dysfunction and conversion to psychosis: Neurocognitive deficits and dyskinesias in the prodromal period.Biological Psychiatry, 68, 93-99.

Mittal, V., Willhite, R. W., Niendam, T., Daley, M. Bearden, C. E., Ellman, L. M., & Cannon, T. D. (2009). Obstetric complications and risk for conversion to psychosis among individuals at high clinical risk, Early Intervention in Psychiatry 3, 226-230.

Mittal, V. A., & Walker, E. F. (2009). Movement abnormalities: a putative biomarker of risk for Psychosis. In Ritsner, M.S. (Ed.) The Handbook of Neuropsychiatric Biomarkers, Endophenotypes, and Genes. Springer: NY (pp. 239-258).

Mittal, V. A., Ellman, L. M. & Cannon, T. D. (2008). Gene-environment interaction and covariation in schizophrenia: The role of obstetric complications. Schizophrenia Bulletin 34, 1083-1094.

Cornblatt, B. A., Walker, E. F., Green, M. F., & Mittal, V. A., (2008). Schizophrenia: Etiology and Neurocognition. In T. Millon, P. H. Blaney, & R. D., Davis (Eds.) Oxford Textbook of Psychopathology (2nd edition). Oxford University Press: New York.

Mittal. V. A., Willhite, R., & Cannon, T. D. (2008). Floaters: A potential confound to the assessment of perceptual abnormalities. Schizophrenia Research 104(1-3), 305-306.

Walker, E. F., Mittal, V. A., & Tessner, K. D. (2008). HPA activity and the developmental course of schizophrenia. Annual Review of Clinical Psychology, 4, 5.1-5.28.

Walder, D. J., Mittal, V. A., Trottman, H. D., McMillan, A. L. & Walker, E. F. (2008). Neurocognition and conversion to psychosis in adolescents at high-risk.Schizophrenia Research, 101, 161-168.

Mittal, V. A., Saczawa, M., Walder, D. J., Willhite, R., & Walker, E.F. (2008). Prenatal viral teratogen exposure and conversion among adolescents at high-risk for psychosis. Schizophrenia Research, 99, 375-376.

Mittal, V. A., Neumann, C., Saczawa, M., & Walker, E. F. (2008). The longitudinal progression of movement abnormalities and psychotic symptoms in adolescents at high-risk for psychosis. Archives of General Psychiatry, 65(2), 165-170.

Walker, E. F., & Mittal, V. A., (2007). External and inherent constraints on progress in psychology: reflections on Paul Wachtel's observations. Applied & Preventive Psychology: Current Scientific Perspectives, 12, 44-46.

Walker, E. F., Bollini, A., Hochman, K., Kestler, L. & Mittal, V. A., (2007). Schizophrenia. In J. E. Maddox & B. A. Winstead (Eds.) Psychopathology: Foundations for a Contemporary Understanding (2nd edition). Lawrence Erlbaum Associates: New York.

Walker, E. F., & Mittal, V. A. (2007). Movement abnormalities- psychosis: Letter to the Editor. Monitor on Psychology, 38(8).

Walker, E. F., McMillan, A., Tessner, K., Mittal, V. A., & Trottman, H. (2007). Adolescent neurodevelopment: A critical period for preventive intervention. In M. Tsuang, W. Stone, & M. Lyons (Eds.), Recognition and Prevention of Major Mental and Substance use Disorders. American Psychological Publishing, Inc: Arlington. pp. 187-213.

Walker, E. F., McMillan, A., & Mittal, V. A. (2007). Neurohormones, Neurodevelopment and the Prodrome of Psychosis in Adolescence. In Walker, E. F. & Romer, D. (Eds.).Adolescent psychopathology and neurodevelopment: integrating brain and preventive science. Oxford University press: USA. pp 264-284.

Mittal, V. A., Hasenkamp, W., Sanfilipo, M., Wieland, S., Burton, A., Rotrosen, J. & Duncan, E. (2007). Relation of neurological soft signs to psychiatric symptoms in schizophrenia. Schizophrenia Research. 94(1-3), 37-44.

Mittal, V. A., & Walker, E. F. (2007). Movement abnormalities predict conversion to Axis I psychosis among prodromal adolescents. Journal of Abnormal Psychology, 116(4), 796-803.

Mittal, V. A., Tessner, K. D., Trottman, H. D., Dhruv, S., Esterberg, M., Simeonova, D., McMillan, A. L., Murphy, E., Saczawa, M. & Walker, E. F. (2007). Movement abnormalities and the progression of prodromal symptomatology in adolescents at risk for psychotic disorders. Journal of Abnormal Psychology, 116(2), 260-267.

Mittal, V. A., Tessner, K. D., & Walker, E. F. (2007). Elevated social Internet use and schizotypal personality disorder in adolescents. Schizophrenia Research, 94(1-3), 50-57.

Mittal, V. A., Dhruv, S., Tessner, K. D. Walder, D. J., & Walker, E. F. (2007). The relations among putative bio risk markers in schizotypal adolescents: minor physical anomalies, movement abnormalities and salivary cortisol. Biological Psychiatry, 61(10), 1179-1186.

Mittal, V. A., Kalus, O., Bernstein, D. P., & Siever, L. J. (2007). Schizoid Personality Disorder. Chapter in O'Donohue, W. O., Lilienfeld, S. T. & Fowler, K. A. (Eds.)Handbook of Personality Disorders: Towards the DSM V. Thousand Oaks: Sage Publications, pp. 63-81.

Mittal, V. A., Tessner, K., Delawalla Z., McMillan, A., Trottman, H. & Walker, E. F. (2006). Gesture behavior in unmedicated schizotypal adolescents. Journal of Abnormal Psychology, 115(2), 351-358.

Corcoran, C., Walker, E. F., Huot, R., Mittal, V. A., Tessner, K., Kestler, K. & Malaspina, D. (2003). The stress cascade and schizophrenia: etiology and onset. Schizophrenia Bulletin, 29(4), 671-692.