Ring

Extensive chloroplast genome rearrangement amongst three closely related Halamphora spp. (Bacillariophyceae), and evidence for rapid evolution as compared to land plants

July 2, 2019

Diatoms are the most diverse lineage of algae, but the diversity of their chloroplast genomes, particularly within a genus, has not been well documented. Herein, we present three chloroplast genomes from the genus Halamphora ( H . americana , H . calidilacuna , and H . coffeaeformis ), the first...

Expression and localization of Zn2+ transporter ZnT3 in cultured neurons by immunofuorescence.

Intracellular Zn2+ transients modulate global gene expression in dissociated rat hippocampal neurons

June 27, 2019

Zinc (Zn 2+ ) is an integral component of many proteins and has been shown to act in a regulatory capacity in different mammalian systems, including as a neurotransmitter in neurons throughout the brain. While Zn 2+ plays an important role in modulating neuronal potentiation and synaptic plasticity, little is...

Evolution Meeting 2019

Chris Smith: Evolution Meeting

June 25, 2019

I just got back from the Evolution Meeting in Providence and I’m full of information and ideas for research. I had the opportunity to reconnect with past colleagues and meet some new people. Other CU Boulder folks attended, including the labs of Dan Doak, Nancy Emery, Nolan Kane, Stacy Smith,...

Satellite image of the greater Boulder/Denver /Colorado Springs area

Evidence of substrate endemism of lichens on Fox Hills Sandstone: Discovery and description of Lecanora lendemeri as new to science

June 5, 2019

Recent lichenological investigations of Fox Hills Formation sandstone outcrops in Colorado resulted in the discovery of three populations that represent an undescribed member of the Lecanora dispersa group (¼Myriolecis). This new species is different from all others in the group in its production of usnic acid, which yields apothecia that...

 Schematic of gRNA binding, R-loop formation and Markov chain model

Development of Novel CRISPR-Based Methods for Transcriptional Control Over Bacterial Gene Expression

May 31, 2019

One of the challenges of the 21st century is creating a sustainable economy that is able to serve the needs of a growing population with the decreasing supply of natural resources. In addition to alternative energy sources, renewable economy concerns production of materials and chemicals. The chemical and polymer industries...

A picture from research performed by John Nardini

The Influence of Numerical Error on Parameter Estimation and Uncertainty Quantification for Advective PDE Models

May 29, 2019

Advective partial differential equations can be used to describe many scientific processes. Two significant sources of error that can cause difficulties in inferring parameters from experimental data on these processes include (i) noise from the measurement and collection of experimental data and (ii) numerical error in approximating the forward solution...

images of adult mouse cardiomyocytes

Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness

May 28, 2019

Numerous diseases, including those of the heart, are characterized by increased stiffness due to excessive deposition of extracellular matrix proteins. Cardiomyocytes continuously adapt their morphology and function to the mechanical changes of their microenvironment. Because traditional cell culture is conducted on substrates that are many orders of magnitude stiffer than...

Inside Hire Ed

Pedigree and Productivity

May 1, 2019

A 2015 study found that “social inequality” across a range of disciplines was so bad that just 25 percent of Ph.D. institutions produced 71 to 86 percent of tenured and tenure-track professors, depending on field. The effect was more extreme the farther up the chain the researchers looked, based on...

Graphs for article of 'Pedigree is not Destiny"

'Pedigree is not destiny' when it comes to scholarly success

May 1, 2019

What matters more to a scientist’s career success: where they currently work, or where they got their Ph.D.? It’s a question a team of researchers teases apart in a new paper published in PNAS . Their analysis calls into question a common assumption underlying academia: that a researcher’s productivity reflects...

A picture from research performed by Christopher Weiss-Lehman

Stochastic processes drive rapid genomic divergence during experimental range expansions

April 10, 2019

Range expansions are crucibles for rapid evolution, acting via both selective and neutral mechanisms. While selection on traits such as dispersal and fecundity may increase expansion speed, neutral mechanisms arising from repeated bottlenecks and genetic drift in edge populations (i.e. gene surfing) could slow spread or make it less predictable...

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