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Dr. Pei-San Tsai is a professor of Integrative
Physiology at the University of Colorado, Boulder. She received
her B.S. from Texas A&M University, and both her M.A.
and Ph.D. from the University of California at Berkeley. Dr.
Tsai's research focuses on the evolution of the structure
and function of gonadotropin-releasing hormone (GnRH), a neurohormone
that is central to the initiation and maintenance of reproduction
in vertebrates, and the development of a small population
of neurons that synthesize GnRH. Current efforts involve the
utilization of molecular, cellular, and physiological techniques
and various vertebrate and invertebrate models to study the
biology of GnRH.
Selected Publications:
P-S Tsai, LR Brooks, JR Rochester, SI Kavanaugh, and WC Chung (2011). Fibroblast growth factor in the developing neuroendocrine hypothalamus. Front Neuroendocrinol 32:95-107.
MJ McCabe, C Gaston-Massuet, V Tziaferi, LC Gregory, KS Alatzoglou, M Signore, E Puelles, D Gerrelli, IS Farooqi, J Raza, J Walker, SI Kavanaugh, P-S Tsai, N Pitteloud, JP Martinez-Barbera and MT Dattani (2011). Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction. J Clin Endocrinol Metab 96:E1709-1718.
B Sun and P-S Tsai (2011). gonadotrophin-releasing hormone-like molecule modulates the activity of diverse central neurons in a gastropod mollusk, Aplysia californica. Front Endocrinol 2:36.
B Sun, SI Kavanaugh and P-S Tsai (2012). Gonadotrophin-releasing hormone in protostomes: Insights from functional studies on Aphasia californica. Gen Comp Endocrinol, in press.
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