Dr. Pei-San Tsai is a professor of Integrative
Physiology at the University of Colorado, Boulder. She received
her B.S. from Texas A&M University, and both her M.A.
and Ph.D. from the University of California at Berkeley. Dr.
Tsai's research focuses on the evolution of the structure
and function of gonadotropin-releasing hormone (GnRH), a neurohormone
that is central to the initiation and maintenance of reproduction
in vertebrates, and the development of a small population
of neurons that synthesize GnRH. Current efforts involve the
utilization of molecular, cellular, and physiological techniques
and various vertebrate and invertebrate models to study the
biology of GnRH.
P-S Tsai, LR Brooks, JR Rochester, SI Kavanaugh, and WC Chung (2011). Fibroblast growth factor in the developing neuroendocrine hypothalamus. Front Neuroendocrinol 32:95-107.
MJ McCabe, C Gaston-Massuet, V Tziaferi, LC Gregory, KS Alatzoglou, M Signore, E Puelles, D Gerrelli, IS Farooqi, J Raza, J Walker, SI Kavanaugh, P-S Tsai, N Pitteloud, JP Martinez-Barbera and MT Dattani (2011). Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction. J Clin Endocrinol Metab 96:E1709-1718.
B Sun and P-S Tsai (2011). gonadotrophin-releasing hormone-like molecule modulates the activity of diverse central neurons in a gastropod mollusk, Aplysia californica. Front Endocrinol 2:36.
B Sun, SI Kavanaugh and P-S Tsai (2012). Gonadotrophin-releasing hormone in protostomes: Insights from functional studies on Aphasia californica. Gen Comp Endocrinol, in press.