Pei-San Tsai

Integrative Physiology; Member of the Center for Neuroscience

Department of Integrative Physiology
N122 Ramaley
University of Colorado
Boulder, CO 80309-0334

Voice (303) 735-1877
FAX (303) 492-4009
Website: http://stripe.Colorado.EDU/~tsaip/

Dr. Pei-San Tsai is a professor of Integrative Physiology at the University of Colorado, Boulder. She received her B.S. from Texas A&M University, and both her M.A. and Ph.D. from the University of California at Berkeley. Dr. Tsai's research focuses on the evolution of the structure and function of gonadotropin-releasing hormone (GnRH), a neurohormone that is central to the initiation and maintenance of reproduction in vertebrates, and the development of a small population of neurons that synthesize GnRH. Current efforts involve the utilization of molecular, cellular, and physiological techniques and various vertebrate and invertebrate models to study the biology of GnRH.

Selected Publications:

P-S Tsai, LR Brooks, JR Rochester, SI Kavanaugh, and WC Chung (2011). Fibroblast growth factor in the developing neuroendocrine hypothalamus. Front Neuroendocrinol 32:95-107.

MJ McCabe, C Gaston-Massuet, V Tziaferi, LC Gregory, KS Alatzoglou, M Signore, E Puelles, D Gerrelli, IS Farooqi, J Raza, J Walker, SI Kavanaugh, P-S Tsai, N Pitteloud, JP Martinez-Barbera and MT Dattani (2011). Novel FGF8 mutations associated with recessive holoprosencephaly, craniofacial defects, and hypothalamo-pituitary dysfunction. J Clin Endocrinol Metab 96:E1709-1718.

B Sun and P-S Tsai (2011). gonadotrophin-releasing hormone-like molecule modulates the activity of diverse central neurons in a gastropod mollusk, Aplysia californica. Front Endocrinol 2:36.

B Sun, SI Kavanaugh and P-S Tsai (2012). Gonadotrophin-releasing hormone in protostomes: Insights from functional studies on Aphasia californica. Gen Comp Endocrinol, in press.