Dr. Pei-San Tsai is a professor of Integrative
Physiology at the University of Colorado Boulder. She received
her B.S. from Texas A&M University, and both her M.A.
and Ph.D. from the University of California at Berkeley. Dr.
Tsai's research focuses on the evolution of the structure
and function of gonadotropin-releasing hormone (GnRH), a neurohormone
that is central to the initiation and maintenance of reproduction
in vertebrates, and the development of a small population
of neurons that synthesize GnRH. Current efforts involve the
utilization of molecular, cellular, and physiological techniques
and various vertebrate and invertebrate models to study the
biology of GnRH.
Kavanaugh SI, Tsai P-S. Functional authentication of a novel gastropod gonadotropin-releasing
hormone receptor reveals unusual features and evolutionary insight. PLoS One 11: e0160292,
Miller AV, Kavanaugh SI, Tsai P-S. Disruption of the suprachiasmatic nucleus in fibroblast growth
factor signaling-deficient mice. Fronters in Endocrinology 7: 11, 1-8, 2016.
Plachetzki DC, Tsai P-S, Kavanaugh SI, Sower SA. Ancient origins of metazoan gonadotropinreleasing
hormone and their receptors revealed by phylogenomic analyses. General and
Comparative Endocrinology 234: 10-19, 2016.
Zhang W, Johnson JI, Tsai P-S. Fgf8-deficient mice compensate for reduced GnRH neuronal
population and exhibit normal testicular function. Frontiers in Endocrinology 6:151, 1-8, 2015.