Christopher A. Lowry

Integrative Physiology; Member of the Center for Neuroscience

Department of Integrative Physiology
Ramaley N379A
University of Colorado
Boulder, CO 80309-0354

Phone: 303-492-6029
Fax: 303-492-0811

Christopher Lowry is an Associate Professor in the Department of Integrative Physiology. He received his Ph.D. in Zoology from Oregon State University in 1995 and subsequently trained at the University of Bristol, UK. In 2002 he was awarded a prestigious Wellcome Trust Research Career Development Fellowship. He joined the University of Colorado Boulder in 2007. He has received 2007 and 2010 Young Investigator Awards from NARSAD, The Brain & Behavior Research Foundation. He has authored or co-authored approximately 100 book chapters, review articles and journal articles. His primary research interest is to understand the neural and physiologic mechanisms underlying the control of anxiety states and emotional behavior, with a focus on the role of serotonergic systems.

Selected Publications:

Lowry CA, Hollis JH, de Vries A, Pan B, Rosa Brunet L, Hunt JRF, Paton JFR, van Kampen E, Knight DM, Evans AK, Rook GAW, Lightman SL. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. Neuroscience 146: 756-772, 2007.

Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA. Adverse experience during early life and adulthood interact to elevate tph2 expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience 163: 991-1001, 2009.

Raison CL, Lowry CA, Rook GA. Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression. Arch Gen Psychiatry 67: 1211-1224, 2010.

Hale MW, Dady KF, Evans AK, Lowry CA. Evidence for In vivo thermosensitivity of serotonergic neurons in the rat dorsal raphe nucleus and raphe pallidus nucleus implicated in thermoregulatory cooling. Exp Neurol 227:264-278, 2011.

Hale MW and Lowry, CA. Functional topography of midbrain and pontine serotonergic systems: implications for synaptic regulation of serotonergic circuits. Psychopharmacology (Berl) 213: 243-264, 2011.