Allan C. Collins

Institute for Behavioral Genetics; Psychology and Neuroscience; Member of the Center for Neuroscience

Institute for Behavioral Genetics, Campus Box 447
Life Sci Bldg (RL#4) Rm 57
University of Colorado at Boulder
Boulder, CO 80309-0447

Phone: 303-492-8752
FAX: 303-492-8063
Website: none

Professor Collins received his Ph.D. in Pharmacology from the University of Wisconsin in 1969, after which he did an NIH Postdoctoral Fellowship at the University of Colorado Medical School. He joined the faculty of the University of Colorado in 1972 and is now a Professor of Pharmacology with the School of Pharmacy and the School of Medicine and a Professor of Psychology in the Department of Psychology. He is a member of several scientific societies, including The Society for Research on Nicotine and Tobacco for which he has served on the Board of Directors. To date he has authored or co-authored 233 scientific articles and 236 scientific abstracts.

Currently Dr. Collins' research focuses on identifying neurochemical systems that play a role in regulating behavioral responses to drugs of abuse, particularly nicotine and alcohol. Because studies with humans indicate that genetic factors regulate addiction to both nicotine and alcohol, Dr. Collins' lab has used genetic strategies to identify neurochemical systems that regulate nicotine and alcohol actions. The long-term goal of his work is to develop drugs that modify critical "addiction-related" systems.

Selected Publications:

Whiteaker, P., McIntosh, J.M., Luo, S., Collins, A.C., and Marks, M.J. [125I]a_-Conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain. Molecular Pharmacology, 2000, 57:913-925.

Grady, S.R., Meinerz, N.M., Cao, J., Reynolds, A.M., Piciotto, M.R., Changeux, J.-P., McIntosh, J.M., Marks, M.J., and Collins, Allan A.C. Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus, a function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry, 76:258-268, 2001.

Stevens, K.E., Bullock, A.E., and Collins, A.C. Chronic corticosterone treatment alters sensory gating in C3H mice. Pharmacology, Biochemistry & Behavior, 69:359-366, 2001.

Vissel, B., Royle, G.A., Christie, B.R., Schiffer, H.H., Ghetti, A., Tritto, T., Perez-Otano, I., Radcliffe, R.A., Seamans, J., Sejnowski, T., Wehner, J.M., Collins, A.C., OÈGormon, S., and Heinemann, S.F. The role of RNA editing of kainate receptors in synaptic plasticity and seizures. Neuron, 29:217-227, 2001.