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Dr. Pei-San Tsai is an assistant professor of Integrative
Physiology at the University of Colorado, Boulder. She received
her B.S. from Texas A&M University, and both her M.A.
and Ph.D. from the University of California at Berkeley. Dr.
Tsai's research focuses on the evolution of the structure
and function of gonadotropin-releasing hormone (GnRH), a neurohormone
that is central to the initiation and maintenance of reproduction
in vertebrates, and the development of a small population
of neurons that synthesize GnRH. Current efforts involve the
utilization of molecular, cellular, and physiological techniques
and various vertebrate and invertebrate models to study the
biology of GnRH.
Selected Publications:
Tsai, P.-S., Moenter, S.M., Postigo, H.R., El Majdoubi, M.,
Pak, T.R., Gill, J.C., Paruthiyil, S., Werner, S., and Weiner,
R.I. (2005). Targeted expression of a dominant negative FGF
receptor in GnRH neurons reduces FGF responsiveness and the
size of GnRH neuronal population. Mol Endocrinol 19:225-236.
Tsai, P.-S., Kessler, A.E., Jones, J.T. and Wahr, K.B. (2005).
Alteration of the hypothalamic-pituitary-gonadal axis in estrogen-
and androgen-treated adult male leopard frog, Rana pipiens.
Reprod Biol Endocrinol 3:2.
Tsai, P.-S. and Jones, J.T. (2005). Steroid-induced changes
in the morphology of GnRH neurons in the male leopard frog,
Rana pipiens: Correlation with plasma gonadotropin and gonadal
size. Gen Comp Endocrinol 141:152-160.
Gill, J.C. and Tsai, P.-S. (2006). Expression of a dominant
negative FGF receptor in developing GnRH1 neurons disrupts
axon outgrowth and targeting to the median eminence. Biol
Reprod.,in Press.
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