| Christopher Lowry is an Assistant Professor
in the Department of Integrative Physiology. He received his
Ph.D. in Zoology from Oregon State University in 1995 and
subsequently trained at the University of Bristol, Bristol,
UK. In 2002 he was awarded a prestigious Wellcome Trust Research
Career Development Fellowship. He joined the University of
Colorado-Boulder in 2007. He has received a 2007 Young Investigator
award from NARSAD: The Mental Health Research Association.
He has authored or co-authored approximately 50 book chapters,
review articles and journal articles. Dr. Lowry’s research
focuses on 3 inter-related areas. His primary research interest
is to understand the neural mechanisms, particularly the role
of the neurotransmitter serotonin, underlying the control
of anxiety states and stress-related physiology. The second
research area of interest is in understanding the mechanisms
through which peripheral immune activation alters serotonergic
neurotransmission in the brain and the consequences for emotional
behavior. The third research area focuses on the effects of
stress on serotonergic neurotransmission in the brain, focusing
on the role of the corticosterone-sensitive family of organic
cation transporters.
Selected Publications:
Lowry CA, Hollis JH, de Vries A, Pan B, Rosa Brunet L, Hunt
JRF, Paton JFR, van Kampen E, Knight DM, Evans AK, Rook GAW,
Lightman SL (2007) Identification of an immune-responsive
mesolimbocortical serotonergic system: potential role in regulation
of emotional behavior. Neuroscience 146: 756-772.
Gasser PJ, Lowry CA, Orchinik M (2006) Corticosterone-sensitive
monoamine transport in the rat dorsomedial hypothalamus: potential
role for organic cation transporter 3 in stress-induced modulation
of monoaminergic neurotransmission. J Neurosci 26:8758-8766.
Abrams JK, Johnson PL, Hay-Schmidt A, Mikkelsen JD, Shekhar
A, Lowry CA (2005) Serotonergic systems associated with arousal
and vigilance behaviors following administration of anxiogenic
drugs. Neuroscience 133(4): 983-997.
Lowry CA, Johnson PL, Hay-Schmidt A, Mikkelsen J, Shekhar
A (2005) Modulation of anxiety circuits by serotonergic systems.
Stress: the International Journal on the Biology of Stress
8(4):233-246.
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