Christopher A. Lowry

Integrative Physiology; Member of the Center for Neuroscience

Department of Integrative Physiology
Ramaley N379A
University of Colorado
Boulder, CO 80309-0354

e-mail: christopher.lowry@colorado.edu
Phone: 303-492-6029
Fax: 303-492-6778
Website: http://www.colorado.edu/kines/faculty/lowry.html

Christopher Lowry is an Assistant Professor in the Department of Integrative Physiology. He received his Ph.D. in Zoology from Oregon State University in 1995 and subsequently trained at the University of Bristol, Bristol, UK. In 2002 he was awarded a prestigious Wellcome Trust Research Career Development Fellowship. He joined the University of Colorado-Boulder in 2007. He has received a Young Investigator award from NARSAD: The Mental Health Research Association. He has authored or co-authored approximately 50 book chapters, review articles and journal articles.
Dr. Lowry’s research focuses on 3 inter-related areas. His primary research interest is understanding the neural mechanisms underlying anxiety states, particularly the role of the neurotransmitter serotonin in the regulation of anxiety states. The second research area of interest is in understanding the mechanisms through which peripheral immune activation alters serotonergic neurotransmission in the brain and the consequences for emotional behavior. The third research area focuses on the effects of stress on serotonergic neurotransmission in the brain, focusing on the role of the corticosterone-sensitive family of organic cation transporters.

Selected Publications:

Lowry CA, Hollis JH, de Vries A, Pan B, Rosa Brunet L, Hunt JRF, Paton JFR, van Kampen E, Knight DM, Evans AK, Rook GAW, Lightman SL (2007) Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. Neuroscience 146: 756-772.


Gasser PJ, Lowry CA, Orchinik M (2006) Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organic cation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci 26:8758-8766.


Abrams JK, Johnson PL, Hay-Schmidt A, Mikkelsen JD, Shekhar A, Lowry CA (2005) Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs. Neuroscience 133(4): 983-997.


Lowry CA, Johnson PL, Hay-Schmidt A, Mikkelsen J, Shekhar A (2005) Modulation of anxiety circuits by serotonergic systems. Stress: the International Journal on the Biology of Stress 8(4):233-246.