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Professor Collins received his Ph.D. in Pharmacology from
the University of Wisconsin in 1969, after which he did an
NIH Postdoctoral Fellowship at the University of Colorado
Medical School. He joined the faculty of the University of
Colorado in 1972 and is now a Professor of Pharmacology with
the School of Pharmacy and the School of Medicine and a Professor
of Psychology in the Department of Psychology. He is a member
of several scientific societies, including The Society for
Research on Nicotine and Tobacco for which he has served on
the Board of Directors. To date he has authored or co-authored
233 scientific articles and 236 scientific abstracts.
Currently Dr. Collins' research focuses on identifying neurochemical
systems that play a role in regulating behavioral responses
to drugs of abuse, particularly nicotine and alcohol. Because
studies with humans indicate that genetic factors regulate
addiction to both nicotine and alcohol, Dr. Collins' lab has
used genetic strategies to identify neurochemical systems
that regulate nicotine and alcohol actions. The long-term
goal of his work is to develop drugs that modify critical
"addiction-related" systems.
Selected Publications:
Whiteaker, P., McIntosh, J.M., Luo, S., Collins, A.C., and
Marks, M.J. [125I]a_-Conotoxin MII identifies a novel nicotinic
acetylcholine receptor population in mouse brain. Molecular
Pharmacology, 2000, 57:913-925.
Grady, S.R., Meinerz, N.M., Cao, J., Reynolds, A.M., Piciotto,
M.R., Changeux, J.-P., McIntosh, J.M., Marks, M.J., and Collins,
Allan A.C. Nicotinic agonists stimulate acetylcholine release
from mouse interpeduncular nucleus, a function mediated by
a different nAChR than dopamine release from striatum. Journal
of Neurochemistry, 76:258-268, 2001.
Stevens, K.E., Bullock, A.E., and Collins, A.C. Chronic corticosterone
treatment alters sensory gating in C3H mice. Pharmacology,
Biochemistry & Behavior, 69:359-366, 2001.
Vissel, B., Royle, G.A., Christie, B.R., Schiffer, H.H.,
Ghetti, A., Tritto, T., Perez-Otano, I., Radcliffe, R.A.,
Seamans, J., Sejnowski, T., Wehner, J.M., Collins, A.C., OÈGormon,
S., and Heinemann, S.F. The role of RNA editing of kainate
receptors in synaptic plasticity and seizures. Neuron, 29:217-227,
2001.
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