| Dr. Bachtell received his Ph.D. in Behavioral
Neuroscience from Oregon Health & Science University in
2004. He then moved to the University of Texas Southwestern
Medical Center at Dallas where he was a post-doctoral fellow
and instructor in the Department of Psychiatry until 2008.
He has since joined the faculty in the Department of Psychology
and Neuroscience at the University of Colorado at Boulder.
The primary research focus of the Bachtell lab is the neurobiology
of drug addiction. Drugs of abuse cause several perturbations
in the brain that contribute to compulsive drug taking and
relapse during periods of abstinence. Studies in the lab utilize
behavioral models of addiction such as drug self-administration
and place conditioning coupled with biochemical measures to
understand the contribution of drug-induced neurobiological
changes on addictive behavior.
Selected Publications:
Bachtell, RK & Self, DW (2008). Renewed cocaine exposure
produces transient alterations in nucleus accumbens AMPA receptor-mediated
behavior. Journal of Neuroscience, 28(48), 12808-14.
Bachtell, RK, Choi, K-H, Monteggia, L, Neve, RL, Self, DW
(2008). Role of GluR1 expression in nucleus accumbens neurons
in cocaine sensitization and cocaine-seeking behavior. European
Journal of Neuroscience, 27(9), 2229-40.
Graham, DL, Edwards, S, Bachtell, RK, DiLeone, RJ, Rios, M
and Self DW (2007). Dynamic BDNF regulation in nucleus accumbens
during cocaine use leads to increased self-administration
and relapse. Nature Neuroscience, 10(8), 1029-1037.
Bachtell, RK, Whisler, K, Karanian, D and Self, DW (2005)
Effects of intra-nucleus accumbens administration of dopamine
agonists and antagonists on cocaine-taking and -seeking behaviors.
Psychopharmacology, 183(1), 41-53.
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