Gene Hayworth attended undergraduate school at UNC-Greensboro. He worked for 10 years as a layout artist, technical writer, computer specialist and training instructor before returning to school at the University of Rochester, where he received a Masters degree in English. He received an MLS from Syracuse University in 1995. He moved to Colorado in 1995 where he worked for CARL Corporation, and in the summer of 1999 he worked for CARL in Singapore, which resulted in the publication of an article about his experiences titled "Singapore Libraries Usher in a New Era," in Computers in Libraries, 20:6 (Nov./Dec. 2000).
In 1998 he published an essay on Coleman Dowell in the encyclopedia Gay and Lesbian Literature published by St. James Press. His critical study of Dowell appeared in The Review of Contemporary Fiction, Fall, 2002, and in February 2003 he prepared an exhibit of the Coleman Dowell papers at the Fales Library, New York University. His critical study of Coleman Dowell, Fever Vision: the life and work of Coleman Dowell, was published by Dalkey Archive Press in 2007. Currently he works as the Faculty Director of the William M. White Business Library at the University of Colorado Boulder.