Aging Laboratory

Institute of Behavioral Genetics

Life Sciences Research Bldgs #1 and #4
Department of Integrative Physiology
University of Colorado
Boulder, CO 80309-0447
phone: 303-492-2929
fax: 303-492-8063

Research Interests

  • The study of aging and stress resistance using the mouse and the nematode worm (Caenorhabditis elegans) as models.
  • The nematode is an excellent system for identifying new longevity and stress resistant genes.
  • The mouse studies focus on identifying genes responsible for stress resistance using a novel stem cell approach.
  • See our detailed IBG research page for the most up-to-date information.

Personnel

  • Director: Thomas E. Johnson, Ph.D.
  • Research Associate: James Cypser, Ph.D.
  • Professional Research Assistant: Patricia Tedesco, B.A.
  • Graduate Student: Breanne Newell, B.S.
  • Undergraduate Students: Katie Cartee, Jerome Castillon, Cody Jackson.
  • Collaborator: Wallace S. Chick, Ph.D., University of Colorado
    Anschutz Medical Campus.

Current Worm Research Projects

  • Health Span and Life Span - Examination of the relationship between health span and functional aging versus life span.
  • Stress Resistance and Life Span - Examination of the relations between life span and stress resistance, using comparative studies of stress resistance versus longevity, stress reporter lines, and forward genetic screens for stress-resistant mutants.

Current Mouse Research Projects

  • Identification of genes influencing stress resistance in the Mouse.
  • Identification of disease resistant loci using transposon induced mutant stem cells.

Funding for Mouse Projects

  • 2012-2017, NIH/NIA, "Identification of Mammalian Genes Promoting Life Extension."

Videos

Recent Publications