Russell L. Moore Russell L. Moore, Ph.D. Department of Integrative Physiology University of Colorado Boulder, CO 80309-0354 phone: 303-492-5209/1093 fax: 303-492-6778 e-mail: russell.moore@colorado.edu

Research Interests

• Identify and understand cellular mechanisms that underlie the physiological (exercise training) and pathological (heart failure, advanced aging) alterations in cardiac contractile function. We are currently conducting work to understand the cellular basis for exercise-induced protection of the heart against ischemia-reperfusion injury, and on the influences of diet and exercise on cardiac energy metabolism and the development of heart failure in the SHHF rat model.


• Cardiac Physiology Laboratory

Education

• 1971-1976, B.S., Department of Biochemistry and Biophysics, University of California, Davis, CA.


• 1976-1982, Ph.D., Exercise Physiology, Washington State University, Pullman, WA.

Professional Experience

• 1981-1984, Postdoctoral Fellow, Pharmacology, University of Texas Health Sciences Center, Dallas, TX.


• 1984-1986, Assistant Professor, Department of Kinesiology, University of Colorado, Boulder, CO.


• 1986-1991, Assistant Professor, Departments of Medicine & Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA.


• 1991-1993, Associate Professor, Departments of Medicine & Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA.


• 1993-1996, Associate Professor, Department of Kinesiology, University of Colorado, Boulder, CO.


• 1993-Present, Associate Professor, Department of Medicine, University of Colorado Health Sciences Center, Denver, CO.


• 1996-2003, Professor, Department of Kinesiology & Applied Physiology, University of Colorado, Boulder, CO.


• 1994-2001, Chair, Department of Kinesiology & Applied Physiology, University of Colorado, Boulder, CO.


• 2001-Present, Professor Adjunct, Department of Medicine (Cardiology), Unversity of Colorado Health Sciences Center, Denver, CO.


• 2003-Present, Professor, Department of Integrative Physiology, University of Colorado, Boulder, CO.


• 2006-Present, Associate Vice Chancellor for Research, University of Colorado, Boulder, CO.

Honors and Awards

• 1984, Cardiology Research Fellow, University of Texas Health Science Center, Dallas, TX.


• 1987, American College of Sports Medicine (National) New Investigator Award.


• 1990-1993, Grant Reviewer for the American Heart Association (PA Affilliate, SE Chapter).


• 1992, Ad hoc Committee Member of PHS NIDA DABR (Pharmacology II) Study Section.


• 1995-1999, Member of PHS Respiratory and Applied Physiology Study Section.


• 1995-Present, Associate Editor, Journal of Applied Physiology.


• 1998-Present, Member of the Board of Governors, University of Colorado Cardiovascular Institute.


• 2002-Present, Ad hoc member of ZRG1 Study Section, a Special Emphasis Panel of the Musculoskeletal Rehabilitation Sciences Study Section.


• 2003, Gollnick Tutorial Lecturer, American College of Sports Medicine.


• 2006, Paul Mole Memorial Lecturer, University of California at Davis.

Recent Publications

• Brown DA, Johnson MS, Armstrong CJ, Lynch JM, Caruso NM, Ehlers LB, Fleshner M, Spencer RL, Moore RL. Short-term treadmill running in the rat: what kind of stressor is it? Journal of Applied Physiology 103:1979-1985, 2007.


• Chicco AJ, Johnson MS, Armstrong CJ, Lynch JM, Gardner RT, Fasen GS, Gillenwater CP, Moore RL. Sex-specific and exercise-acquired cardioprotection are abolished by sarcolemmal K_ATP channel blockade in the rat heart. American Journal of Physiology 292: H2432-H2437, 2007.


• Chicco, AJ, McCune SA, Emter CA, Sparagna GC, Rees ML, Bolden DA, Marshall KD, Murphy RC, Moore RL. Low-intensity exercise training improves survival in female hypertensive heart failure rats. Hypertension 51: 1096Ð1102, 2008.


• Chicco, AJ, Sparagna GC, McCune SA, Johnson CA, Murphy RC, Bolden DA, Rees ML, Gardner RT, Moore RL. High fat diet rich in linoleate decreases mortality in SHHF rats compared to lard and low fat diets. Hypertension 52: 1-7, 2008


• Sparagna GC, Chicco AJ, Murphy RC, Bristow MR, Johnson CA, Rees ML, Maxey ML, McCune SA , Moore RL. Loss of cardiac tetralinoleoyl cardiolipin in human and experimental heart failure. Journal of Lipid Research 48: 1559-1570, 2007.


• Watson PA, Reusch JE-B, McCune SA, Leinwand LA, Luckey SW, Konhilas JJP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. American Journal of Physiology 293: J246-H259, 2007.