Christopher A. Lowry Christopher A. Lowry, Ph.D. Department of Integrative Physiology University of Colorado Boulder, CO 80309-0354 phone: 303-492-6029 fax: 303-492-6778 e-mail: christopher.lowry@colorado.edu

Research Interests

• The neural mechanisms underlying emotional behavior and the stress-induced regulation of emotional behavior


• Behavioral Neuroendocrinology Laboratory

Education

• 1983-1987, B.A. Hons., University of Wyoming, Laramie, Wyoming


• 1987-1995, Ph.D., Oregon State University, Corvallis, Oregon

Professional Experience

• 1995-2002, Postdoctoral Research Fellow, University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK.


• 2002-2003, Neuroendocrinology Charitable Trust Research Fellow, University Research Centre for Neuroendocrinology, University of Bristol, Bristol, UK.


• 2003-2007, Wellcome Trust Intermediate Level Research Fellow, Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol, UK.


• 2007-Present, Assistant Professor, Department of Integrative Physiology, University of Colorado, Boulder.

Honors and Awards

• 1983-1987, University of Wyoming Honors and Scholars Program


• 1992-1994, National Institute of Mental Health National Research Service Award (NRSA) Predoctoral Fellowship


• 2002-2003, Research Fellow, Neuroendocrinology Charitable Trust


• 2003-2007, Research Fellow, The Wellcome Trust


• 2007, Young Investigator Award, NARSAD


• 2009-2014, National Science Foundation (NSF) CAREER Award

Recent Publications

• Evans AK, Heerkens JLT, Lowry CA. Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus. Neuroscience Letters 455(1): 36-41, 2009.


• Feng N, Telefont M, Kelly K, Orchinik M, Forster GL, Renner KJ, Lowry CA. Local perfusion of corticosterone in the rat medial hypothalamus potentiates D-fenfluramine-induced elevations of extracellular 5-HT concentrations. Hormones and Behavior 56: 149-157, 2009.


• Gardner KL, Hale MW, Lightman SL, Plotsky PM, Lowry CA. Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression. Brain Research 1305: 47-63, 2009.


• Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA. Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience 163: 991-1001, 2009.


• Gasser PJ, Lowry CA, Orchinik M. Rapid corticosteroid actions on behavior: Mechanisms and implications. In: Hormones, Brain and Behavior, 2nd Edition. Pfaff D, Arnold A, Etgen A, Fahrbach S, Rubin R (Eds). Elsevier, Oxford, UK. ISBN: 978-0080887838, 2009


• Gasser PJ, Orchinik MO, Raju I, Lowry CA. Distribution of organic cation transporter 3, a corticosterone-sensitive monoamine transporter, in the rat brain. Journal of Comparative Neurology 512: 529-555, 2009.


• Lowry CA, Hale MW, Burke KA, Renner KJ, Moore FL. Fluoxetine potentiates the effects of corticotropin-releasing factor on locomotor activity and serotonergic systems in the roughskin newt, Taricha granulosa. Hormones and Behavior 56: 177-184, 2009.


• Lowry CA, Hale MW, Plant A, Renner KJ, Windle RJ, Shanks N, Wood SA, Ingram CD, Lightman SL, Summers CH. Fluoxetine inhibits corticotropin-releasing factor (CRF)-induced behavioural responses in rats. Stress 12(3): 225-239, 2009.


• Lowry CA, Lightman SL, Nutt DJ. That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion. Journal of Psychopharmacology 23(4): 392-400, 2009.


• Lukkes JL, Watt MJ, Lowry CA, Forster GL. The long-term consequences of early-life social isolation on anxiety-related neural circuits and behavior in rodents. Frontiers in Behavioral Neuroscience 3:18, 2009. doi:10.3389/neuro.08.018.2009.


• Nutt DJ, Lowry CA. How can we use current knowledge to improve antidepressant treatments? In: Understanding depression: A translational approach, Pariante CM, Ed. Oxford University Press, Oxford. ISBN: 978-0199533077, 2009


• Orchinik M, Gasser P, Lowry CA. Acute corticosteroid actions in the brain: cellular mechanisms and behavioral consequences. In: Molecular Mechanisms of Hormone Actions on Behavior. Pfaff D, Etgen A (Eds), Academic Press, San Diego, CA. ISBN: 978-0123749390, 2009.


• Rook GAW, Lowry CA. The hygiene hypothesis and affective and anxiety disorders. In: The Hygiene Hypothesis and Darwinian Medicine, Rook GAW (Ed), Vol. 1, Progress in Inflammation Research, Parnham M (Ed). Birkhauser Publishing, Basel, Switzerland. ISBN: 978-3764389024, 2009.