Christopher A. DeSouza Christopher A. DeSouza, Ph.D. Department of Integrative Physiology University of Colorado Boulder, CO 80309-0354 phone: (303) 492-2988 fax: (303) 492-6778 e-mail: desouzac@stripe.colorado.edu

Research Interests

• Effects of aging, cardiovascular and metabolic risk factors, and regular physical activity on nitric oxide bioavailability and vascular endothelial function.


• Integrative Vascular Biology Laboratory

Education

• 1984-1988, B.P.H.E., University of Toronto, Toronto, Canada.


• 1989-1991, M.A., The George Washington University, Washington, D.C.


• 1991-1995, Ph.D., University of Maryland, College Park, MD.

Professional Experience

• 1995-1999, Research Associate, Department of Kinesiology and Applied Physiology, University of Colorado, Boulder, CO.


• 1999-2003, Assistant Professor, Department of Kinesiology and Applied Physiology, University of Colorado, Boulder, CO.


• 2003-2005, Assistant Professor, Department of Integrative Physiology, University of Colorado, Boulder, CO.


• 2005-2010, Associate Professor, Department of Integrative Physiology, University of Colorado, Boulder, CO.


• 2004-2009, Assistant Program Director, UC-Boulder, General Clinical Research Center.


• 2009-present, Co-Director, UC-Boulder, Clinical and Translational Research Center.


• 2010-present, Professor, Department of Integrative Physiology, University of Colorado, Boulder, CO.

Honors and Awards

• 1999, Clinical Research Award, American Diabetes Association


• 2001 CU-Boulder, Junior Faculty Development Award.


• 2002, Clinical Research Award, American Diabetes Association


• 2005 Member, Clinical and Integrative Cardiovascular Sciences Study Section, National Institutes of Health


• 2008, Established Investigator Award, American Heart Association.

Recent Publications

• Weil BR, Westby CM, Van Guilder GP, Greiner JJ, Stauffer BL, DeSouza CA. Enhanced endothelin-1 system activity with overweight and obesity. American Journal of Physiology 301: H689-695, 2011.


• Weil BR, Stauffer BL, Mestek ML, DeSouza CA. Influence of abdominal obesity on vascular endothelial function in overweight/obese adult men. Obesity 19: 1742-1746, 2011.


• Weil BR, Stauffer BL, Greiner JJ, DeSouza CA. Prehypertension in associated with impaired nitric oxide-mediated endothelium-dependent vasodilation in sedentary adults. American Journal of Hypertension 24: 976-981, 2011.


• Westby CM, Weil BR, Greiner JJ, Stauffer BL, DeSouza CA. Endothelin-1 vasoconstriction and the age-related decline in endothelium-dependent vasodilation in men. Clinical Science 120: 485-491, 2011.


• Kushner EJ, MacEneaney OJ, Weil BR, Greiner JJ, Stauffer BL, DeSouza CA. Aging is associated with a proapoptotic endothelial progenitor cell phenotype. Journal of Vascular Research 48: 408-414, 2011.


• Weil BR, MacEneaney OJ, Stauffer BL, DeSouza CA. Habitual short sleep duration and circulating endothelial progenitor cells. Journal of Cardiovascular Disease Research 2: 110-114, 2011.


• MacEneaney OJ, Connick E, DeSouza CA. Effects of HIV-1 gp120 and protease inhibitors on apoptotic susceptibility of CD34+ hematopoietic progenitor cells. Journal of Acquired Immune Deficiency Syndrome 56: e49-50, 2011.


• MacEneaney OJ, DeSouza CA, Weil BR, Kushner EJ, Van Guilder GP, Mestek ML, Greiner JJ, Stauffer BL. Prehypertension and endothelial progenitor cell function. Journal of Human Hypertension 25: 57-62, 2011.