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David L. Allen
David L. Allen, Ph.D.
Department of Integrative Physiology
University of Colorado
Boulder, CO 80309-0354
phone: (303) 492-3175
fax: (303) 492-0811
e-mail: allendl@colorado.edu
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Research Interests
- Transcriptional regulation of skeletal muscle gene expression.
- Molecular basis of skeletal muscle adaptation to exercise, disease, and aging.
Molecular mechanisms underlying exercise-induced muscle damage and repair.
- Molecular genetics of addiction.
- Molecular and Cellular Physiology Laboratory
Education
- 1985-1991, B.S., Department of Kinesiology, University of California, Los Angles, CA.
- 1991-1996, Ph.D., Department of Physiological Science, University of California, Los Angeles, CA.
Professional Experience
- 1996-1998, Postdoctoral Research Fellow, Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI.
- 1998-2004, Research Associate, Department
of Molecular, Cellular, and Developmental Biology, University of
Colorado, Boulder, CO.
- 2004-present, Assistant Professor, Department of Integrative Physiology, University of
Colorado, Boulder, CO.
Honors and Awards
- 1996-1998, University of Michigan Cardiovascular Center, NIH Postdoctoral Training Grant .
- 1998-2002, Muscular Dystrophy Association, Research Development Grant.
- 2000, Recipient of the Carl Gisolfi Travel Award for the Integrative Biology of Exercise Conference.
- 2004-2008, Mentored Research Scientist Development Award,
National Institutes of Health
- 2005, Shih Chun Wang Young Investigator Award, American Physiological Society
- 2005, Research Endowment Award, American College of Sports Medicine
- 2007, American Physiological Society Research Career Enhancement Award Mentor for Dr. Min Du, University of Wyoming, $1500.00
- 2008, Travel award, NIH Workshop on The Establishment, Maintenance, and Turnover of Adipose Depots
Recent Publications
- Allen DL. Making sense (and antisense) of myosin heavy chain gene expression. Am J Physiol: Reg Int Physiol 2008.
- Allen DL, Cleary AS, Lindsay SF, Speaker KJ, Uyenishi J, Reed JM, Madden MC, Mehan RS. Myostatin, activin Receptor IIb, and follistatin-Like-3 gene expression is altered in adipose tissue and skeletal muscle of obese mice. Am J Physiol: Metab and Endoc, 294: E918-E927, 2008.
- Allen D, Du M. Comparative functional analysis of the cow and mouse myostatin genes reveals novel regulatory elements in their upstream promoter regions. Comp Biochem Physiol 2008.
- Allen DL, Weber JN, Sycuro LK, Leinwand LA. Myocyte enhancer factor-2 and serum response factor binding elements regulate fast myosin heavy chain transcription in vivo. Journal of Biological Chemistry 280: 17126-17134, 2005.
- Allen DL, Unterman TG. Regulation of myostatin expression and myoblast differentiation by SMAD and FoxO transcription factors. Am J Physiol Cell Physiol 292: C188-199, 2007.
- Beylkin DH, Allen DL, Leinwand LA. MyoD, Myf5 and the calcineurin pathway activate the developmental myosin heavy chain genes. Developmental Biology 294: 541-553, 2006.
- Bryan A, Hutchison KE, Seals DS, Allen DL. A transdisciplinary model integrating genetic, physiological, and psychological correlates of voluntary exercise. Health Psychology 26: 30-39, 2007.
- Hutchison KE, Allen DL, Jepson C, Lerman C, Benowitz N, Stitzel J, Bryan AB, McGeary J, Haughey HM. CHNA4 and tobacco dependence: from gene regulation to treatment outcome. Arch Gen Psychiatry 64: 1078-86, 2007.
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