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Molecular Genetics

Publication Highlights:

1.    Tammimäki A, *Herder P, Li P, Esch C, Laughlin JR, Akk G, Stitzel JA. 2012. Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors. Neuropharmacology 63:1002-11

2.    Haller G, Druley T, Vallania FL, Mitra RD, Li P, Akk G, Steinbach JH, Breslau  N, Johnson E, Hatsukami D, Stitzel J, Bierut LJ, Goate AM. 2012. Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. Hum Mol Genet. 21:647-55

3.    Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM; COGEND collaborators and GELCC collaborators. 2009. Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. Hum Mol Genet. 18:3125-35

4.    Brooks N, Mexal S, and Stitzel JA. 2009. Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels. Brain Research 1263:1-9.