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updated annually

 

Select Publications (listed alphabetically, grouped by year published)

2007

Benoit, M. and Klaus, D.M. (2007) “Microgravity, Bacteria, and the Influence of Motility” Advances in Space Research, 39(7): 1225-1232

 

Clawson, J. (2007) Title:  Durability and design approaches in the use of flexible transparent polymer films for a Mars greenhouse application. Doctoral Thesis, University of Colorado

 

Geschwill, L., Massey, D., Kobrick, R., Kanner, L. and Klaus, D (2007) Educational Opportunities Supporting the Development of a Full-Scale Mockup of the New Lunar Lander at the University Level: A Case Study. AIAA Region V Student Paper Conference and Competition, US Air Force Academy, Colorado Springs, CO, April 2007 (received 3rd Place Award, Team Category)

 

Gifford, K.K., Braham, S., (2007) "Wireless network systems to support NASA's Exploration Vision" AIAA InfoTech@Aerospace 2007, Paper # AIAA-2007-2927, Rohnert Part, CA.

 

Hoehn, A., Countryman, S., Freeman, J., Gifford, K., Goulart, C., Kalinowski, W., Koenig, P., Kusminski, S., Williams, S., and Stodieck, L. (2007) “Science Research and Education Modules for the CGBA Spaceflight Incubator” SAE Technical Paper 2007-01-3188.

 

Hoehn, A., Lynch, K., Clawson, J., Kapit, J., Young, S., Kounaves, S. and Brown, I. (2007) “Microbial Detection Array (MDA), a Novel Instrument for Unambiguous Detection of Microbial Metabolic Activity” SAE Technical Paper in Astrobiology Applications 2007-01-3190.

 

Johanson, K., Allen, P, Gonzalez-Villalobos, R., Nesbit, J., Nickerson, C., Höner zu Bentrup, K., Wilson, J., Ramamurthy, R., D’Elia, R., Muse, K., Hammond, J., Freeman, J., Stodieck, L. and Hammond, T. (2007) “Haploid deletion strains of Saccharomyces cerevisiae that determine survival during space flight” Acta Astronautica, 60(4-7):460-471

 

Klaus, D. (2007) Life Sciences (Air and Space Year in Review) Aerospace America 12: 87

 

Klaus, D.M., Metts, J., Kobrick, R., Mesloh, M., Monk, T., Gauthier, E., Eberhart, K., Baca, D., Wright, C., Gustafson, A., Oryshchyn, L. and Massey, D. (2007) “Space Suit Concepts and Vehicle Interfaces for the Constellation Program” SAE Technical Paper 2007-01-3088

 

Kobrick, R.L., and D.B. Spencer (2007) "Optimizing Trajectories for Suborbital Human Spaceflight" Journal of Spacecraft and Rockets, Vol. 44, No. 2

 

Kounaves, S. P.,  Brown, I. I., Galindo, C. , Hoehn, A., Kapit, J., Lynch, K., McKay, D., Sarkisova, S. and Young, S. (2007) “Detection of Microbial Life in Soil Based on Minimal Assumptions Using Measurements of Physical and Chemical Changes Induced by Growth” 7th International Conference on Mars” Pasadena, CA.

 

Lee, J.S., Klaus, D.M., Maness, P.C. and Spear, J.R. (2007) The Effect of Butyrate Concentration on Hydrogen Production via Photofermentation for use in a Martian Habitat Resource Recovery Process. International Journal of Hydrogen Energy 32 (15): 3301– 3307

 

Russell, J.F. and Klaus, D.M. (2007) “Maintenance, Reliability and Policies for Spacecraft Life Support Systems on Orbital Space Stations” Reliability, Engineering and Systems Safety 92(6): 808-820.

2006

Aponte, V. M., Finch, D. S., and Klaus, D. M. (2006) Considerations for non-invasive in-flight monitoring of astronaut immune status with potential use of MEMS and NEMS devices. Life Sciences Journal 79(14): 1317-1333

 

Benoit, M.R., Li, W., Stodieck, L.S., Lam, K.S., Winther, C.L., Roane, T.M. and Klaus, D.M. (2006) Microbial Antibiotic Production Aboard the International Space Station. Applied Microbiology and Biotechnology, 70(4): 403-411

 

Chappell, S.P. and Klaus, D.M. (2006) Enhanced simulation of partial gravity for extravehicular activity. Journal of Human Performance in Extreme Environments 9(1)

 

Chappell, S.P., Klaus, D.M. and Parazynski, S.E. (2006) Access Systems for Partial Gravity Exploration & Rescue: Engineering Analysis & Design, SAE Technical Paper 2006-01-2291

 

Gifford, K.K., Kuzminsky, S., Williams, S., and Saiz, J., "BioNet: A developer-centric middleware architecture for heterogeneous devices and protocols" IEEE Wireless Communications and Networking Conference, Las Vegas, NV, April, 2006.

 

Hanson AM, Young MH, Stodieck LS, Ferguson VL (2006) "Longitudinal Hindlimb Suspension Study Reveals Physical, Functional and Biochemical Changes in Mouse Skeletal Muscle." Poster Presentation, Annual Meeting of the American Society for Gravitational and Space Biology, Arlington, VA Gravitational and Space Biology, 20(1):16

 

Hatfield, T., Klaus, D. and Simske, S. (2006) Ultrasonic 360º Cross Section Scanning Methodology for Monitoring Bone and Muscles Areas During Space Flight. Microgravity Science and Technology XVIII(1): 15-21

 

Hoehn, A.,  J.B. Freeman, P. Koenig, L.S. Stodieck, M. Vellone, S. Williams, J. deLuis, W. Feenstra, J.C. Parrish, S. Pretorius, L. Sun, S. Dyble, N. Searby, D. Vandendriesche (2006): " Single Loop for Cell Culture (SLCC) – Development and Spaceflight Qualification of a Perfusion Cell Culture System", SAE-paper 2006-01-2212, International Conference Environmental Systems (ICES), July 2006, Norfolk, Virginia.

 

Heyenga, A.G., C. Blackford, R.N. Bowman, M.H. Kliss, "Optimization of Extraterrestrial Plant Biology Research Through the Use of Standardized Plant Cultivation and Analysis Technologies", SAE-paper 2006-01-2213, International Conference Environmental Systems (ICES), July 2006, Norfolk, Virginia.

 

Klaus, D.M. and Howard, H.N. (2006) Antibiotic Efficacy and Microbial Virulence during Space Flight. Trends in Biotechnology 24(3):131-6

 

Klaus, D., Bamsey, M., Schuller, M., Godard, O., Little, F. and Askew, R. (2006) Defining Space Suit Operational Requirements for Lunar and Mars Missions and Assessing Alternative Architectures. SAE Technical Paper 2006-01-2290

 

Kobrick, R.L., Battler, M. M., Persaud, R., Wilkinson, N. (2006) “Training a crew for human exploration by using Mars analogue research stations” 57th International Astronautical Congress. Space Education and Outreach Symposium, Space Exploration Education session, IAC-06-E1.5.04, Valencia, Spain.

 

Kobrick, R.L., Dara, S., Burley, J., and Gill, S. (2006): “A New Countermeasure Device For Long Duration Space Flights” Acta Astronautica, 58: 523-536.

 

Kounaves, S.P., Lynch, K.L., Brown, I. I., Hoehn, A., McKay, D.S., Young S.M.M. (2006) Microbial Detection Array. Astrobiology 6(1): 282 [Epub DOI:10.1089/ast.2006.6.247]

 

Russell, J., Klaus, D. and Mosher, T. (2006) Applying Analysis of International Space Station Crew-Time Utilization to Mission Design. J Spacecraft and Rockets 43(1): 130-136.

 

Plancke, P., Saiz, J., Hernandez-Velasco, I., Gifford, K.K., and Carron, C., "Wireless Communications and Interfaces onboard Spacecraft" AIAA SpaceOps 2006 Conference, Rome, Italy, June, 2006.

 

Schuller, M., Klaus, D., Lalk, T., Wiseman, L., Thomas, G., Little, F., Godard, O., Kobrick, R., Abdel-Fattah, S., Rouen, M. and Askew, R. (2006) Innovative Schematic Concept Analysis for a Space Suit Portable Life Support Subsystem, SAE Technical Paper 2006-01-2201

 

Stroud, K.J. and Klaus, D.M. (2006) Spacecraft Design Considerations for Piloted Reentry and Landing. J. British Interplanetary Society 59(12): 426-442

2005

Bandstra ER, Barth JL, Argraves WS, Harrison BC, Bateman TA (2005) “Microarray Analysis of Spaceflown Mouse Gastrocnemius.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH.

 

Bateman, TA (2005) “Spaceflight as a biomedical test-bed for bone loss countermeasures and candidate osteoporosis therapies.”  In IAA Humans in Space.

Benoit, M.R. (2005) Responses, Applications, and Analysis of Microgravity Effects on Bacteria.  Doctoral Thesis, University of Colorado, Boulder

Benoit, M.R. and Klaus, D.M. (2005). “Can genetically modified Escherichia coli with neutral buoyancy induced by gas-vesicles be used as an alternative method to clinorotation for microgravity studies?” Microbiology 151(1): 69-74.

 

Benoit, M.R., Nelson, E.S. and Klaus, D.M. (2005) “Mathematical Analysis and Numerical Modeling of Buoyant Flow from Solute Gradients around Growing Escherichia coli Cells” (abstract) Gravitational and Space Biology Bulletin 19(1): p. 21 and (poster) ASGSB 21st Annual Meeting, Reno, NV

 

Benoit, M. R., Nelson, E. S., and Klaus, D. M. (2005) “Numerical model simulations of buoyant plumes resulting from solute gradients around metabolizing bacteria.”  In Proceedings of the COMSOL Multiphysics™ Conference, Cambridge, MA, October 23-25, pp. 63-69.  

 

Cannon, C.M., Dieter-Seelig, H., Stodieck, L.S., Hanson, A.M., Simske, S.J., Ferguson, V. L. (2005) "A novel combination of methods to assess sarcopenia and muscle performance in mice." Biomed Scie Instrum. 41: 116-121.

 

Clawson, J. M. and A. Hoehn (2005). “Stress-Accelerated Photodegradation of Space-Rated Flexible Transparent Films Exposed to Mars Surface UV.” SAE-paper: 2005-01-2775, In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Clawson, J. M. and A. Hoehn (2005). “Global Estimates of the Photosynthetically Active Radiation at the Mars Surface.” SAE-paper: 2005-01-2813 In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Clawson, J. M., A. Hoehn, et al. (2005). Inflatable Transparent Structures for Mars Greenhouse Applications. SAE -paper: 2005-01-2846, In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Gifford, K., Kuzminsky, S. and Williams, S. (2005) "An Integrated Architecture for Advanced Environmental and Physiological Monitoring." SAE Paper 2005-01-2874 In International Conference on Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Goulart, Carla V., Woodard, Sherry, and Campbell, Kimberly. (2005) “STARS™ (Science Technology and Research Students): A Hands-on, Interactive, Scientific and Cultural Exchange Lesson.” SAE-paper 2005- 01-3102,  In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Hamilton, SA, Gridley, DS, Pecaut, MJ, Bateman, TA (2005) “Osteoblast and Osteoclast Response to Radiation Induced Bone Loss.”  In Radiation Research Society Annual Meeting Proceedings.

 

Hamilton, SA, Gridley, DS, Pecaut, MJ, Bateman, TA (2005) “Radiation affects the microarchitecture of bone.” In 27th American Society for Bone and Mineral Research Annual Meeting Proceedings

 

Hamilton, SA, Gridley, DS, Pecaut, MJ, and Bateman, TA  (2005) “The Effects of Radiation on Murine Bone Loss.” In  Proceedings of the 15th Human in Space Symposium, Graz, International Academy of Astronautics 15:85. 

 

Hamilton, SA, Pecaut, MJ, Gridley, DS, Harris, LG, and Howard, SH (2005) “Low-dose ionizing radiation induces murine bone loss.”  In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

 

Hamilton, SA, Gridley, DS, Pecaut, MJ, and Bateman, TA  (2005) “Osteoblast and Osteoclast Response to Radiation Induced Bone Loss.” In Radiation Research Society Annual Meeting Proceedings

 

Hanson, A.M., Ferguson, V.L, Simske, S.J., Cannon, C.M., Stodieck, L.S.  (2005) “Comparison of tail-suspension and sciatic nerve crush on the musculoskeletal system in young-adult mice.” Biomed Sci Instrum. 41:92-6, 2. 

 

Hanson, A.M., Simske, S.J, Stodieck, L.S, Cannon, C.A., Ferguson, V.L. (2005) “Investigating Voluntary Wheel Running as a Recovery Method for Tail Suspension Induced Sarcopenia” Gravitational and Space Biology Bulletin 19(1): p. 10 and (poster) ASGSB 21st Annual Meeting, Reno, NV

 

Heÿenga, G., Kliss, M., and Blackford, C. (2005): "The Performance of a Miniature Plant Cultivation System Designed for Space Flight Application", SAE-paper: 2005-01-2844. In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Hoehn, A., Clawson, J.M., Higgins, C., Jairala, J., Journey-Kahler, P., Lee, J., and Stodieck, L. (2005): “Carbon Dioxide Scrubbers for Controlling the Gaseous Composition of Spaceflight Plant Growth Chambers – Design Trades and Test Results.” SAE-paper: 2005-01-2954, In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Hoehn, A., Clawson, J.M., Freeman, J.B., and Stodieck, L.S. (2005): "Temperature and Humidity Control Capabilities and Limitations of a Spaceflight Plant Growth Chamber." SAE-paper: 2005-01-2845. In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy. 

 

Howard, H.N. and Klaus, D.M. (2005) “Containment Geometry Considerations for Space Flight and Simulated Microgravity Microbiology Experiments” (abstract) Gravitational and Space Biology Bulletin 19(1): p. 11 and (poster) ASGSB 21st Annual Meeting, Reno, NV

 

Howard, SH, Hamilton, SA, Harris, LG, Pecaut, MJ, Gridley, DS, Obenaus, A, and Bateman, TA (2005) “Heavy ion iron radiation causes bone loss in rats.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

 

Klaus, D. M., Adams, A. C., Bamsey, M., Cragg, M., Ellis, T., Higgins, C. D., Howard, H. N., Jairala, J., Kelly, E. A., Krauser, W. R., McFarland, S. M., and Vellone, M. M. (2005): "Spacecraft Life Support System Design Guidelines for Human Exploration of the Moon and Mars", SAE-paper: 2005-01-3008. In International Conference Environmental Systems (ICES) Proceedings, Rome, Italy.

 

Lau, AG, Yuan, YY, Kostenuik, PJ, Morony, S, Adamu, S, Asuncion, F, and Bateman, TA (2005) “RANKL Has Detrimental Effects on Cortical and Trabecular Bone Volume, Mineralization, and Bone Strength in Mice.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

 

Lloyd, SAJ, Cheluvaraju, C, Hamilton, SA, and Bateman, TA. (2005) “Determination of Minimum, Efficacious Comparable Doses of Zoledronate and Osteoprotegerin: Maximizing Bone Mass and Turnover.”  In Annual Meeting of the American Society of Gravitational and Space Biology Proceedings.

 

Miesse, AM and Bateman, TA (2005) “Gender Response to Regenerative Nerve Damage-Induced Bone Loss.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

 

Miesse, AM and Bateman, TA (2005) “Gender Response to Regenerative Nerve Damage-Induced Bone Loss.” In  27th American Society for Bone and Mineral Research Annual Meeting Proceeedings

 

Mohr, KE, Recknor, CP, Recknor, JC, and Bateman, TA (2005) “Retrospective analysis of teriparatide as a therapy for osteoporosis.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

Russell, J.F. (2005) Expanded Life-Cycle Analysis to Optimize Spacecraft Life Support System Design.  Doctoral Thesis, University of Colorado, Boulder

Russell, J.F. and Klaus, D.M. (2005) “Anticipated Extravehicular Activity Time on the Lunar Surface Based on ISS Operations” Space 2005, AIAA 2005-6697

 

Seelig, H.D. (2005) The Assessment of Water Deficit Stress in Plants using Optical Measurement Methods.  Doctoral Thesis, University of Colorado, Boulder

 

Stroud, K.J., Harm, D.L. and Klaus, D.M. (2005) “Preflight Virtual Reality Training as a Countermeasure for Space Motion Sickness and Disorientation” Aviation, Space and Environmental Medicine 76:352-356

 

Yuan, YY, Kostenuik,, PJ, Morony, S, Adamu, S, Asuncion, F. and Bateman, TA (2005) “Continuous Administration of RANKL Caused High Bone Turnover and Bone Loss in Rats.” In Bone Loss during Spaceflight Symposium Proceedings, Cleveland Clinic, Cleveland, OH

 

Yuan, YY, Lau, AG, Kostenuik,, PJ, Morony, S, Adamu, S, Asuncion, F, and Bateman, TA (2005) “RANKL Has Detrimental Effects on Cortical and Trabecular Bone Volume, Mineralization and Bone Strength In Mice.” In ASBMR Bone Quality Meeting Proceedings

 

Yuan, YY, Lau, AG, Kostenuik,, PJ, Morony, S, Adamu, S, Asuncion, F, and Bateman, TA (2005) “RANKL Has Detrimental Effects on Cortical and Trabecular Bone Volume, Mineralization and Bone Strength In Mice.”  27th American Society for Bone and Mineral Research Annual Meeting

2004

Bandstra ER, Barth JL, Argraves WS, Bateman TA (2004) “Analysis of gene array changes in muscle caused by spaceflight.”  Grav Space Biol Bul 18:12.  (abstract)

Bateman TA (2004) “Molecular therapies for disuse osteoporosis.”  Grav Space Biol Bul 17:83-89.

Bembey AK, Koonjul A, Bushby AJ, Ferguson VL, Boyde A.  (2004) “Contribution of collagen, mineral and water phases to the nanomechanical properties of bone.” Fall 2004 MRS Proceedings: Fundamentals of Nanoindentation and Nanotribology III.

Benoit, M.R. and Klaus. D.M. (2004) “Mitigating the Effects of Clinorotation on Escherichia coli through Induced Cellular Neutral Buoyancy” (abstract) Gravitational and Space Biology Bulletin 18(1): p. 21

Bushby AJ, Ferguson VL, Boyde A. (2004) “Nanoindentation of bone: comparison of specimens tested in liquid and embedded in PMMA.”  J Mat Res, 19:249-259.

Chappell SP and Klaus DM (2004) “Adaptation of terrestrial mountaineering equipment and training methods for planetary EVA operations.” 34th ICES, SAE Technical Paper ICES 2004-01-2290

Clark KL, Oelke A, Johnson ME, Eilert KD, Simpson PC, Todd SC  (2004) “CD81 associates with 14-3-3 in a redox-regulated palmitoylation-dependent manner.”  J Biol Chem 279:19401-19406.

Czupalla M, Aponte V, Chappell S, Klaus D (2004) “Analysis of a spacecraft life support system for a Mars mission.” Acta Astronautica 55:537-547.

Ferguson VL, Bushby AJ, Boyde A. (2004) “Elastic modulus of dental enamel: Effect of enamel prism orientation and mineral content.” Fall 2004 MRS Proceedings: Fundamentals of Nanoindentation and Nanotribology III.

Goulart CV, Woodard S, Rupert M, Stodieck LS (2004) “Performance of the STARS life sciences habitats in spaceflight and ground controls.” 34th ICES, SAE Technical Paper ICES 2004-01-2394.

Harris LG, Pecaut MJ, Obenaus A, Nelson GA, Gridley DS, Bateman TA (2004) “The effects of radiation on the rat bone.”  Grav Space Biol Bul 18:20.  (abstract)

Hatfield, T.R. (2004) Development of Novel Ultrasonic Physiological Measurement Methodologies Appropriate for Space Flight.  Doctoral Thesis, University of Colorado, Boulder

Hatfield TR, Klaus DM, Simske SJ (2004) “An ultrasonic methodology for muscle cross section measurement to support spaceflight.” Micrograv Sci and Tech, 15(3)3-11.

Heyenga AG, Stodieck LS, Hoehn A, Kliss M, Blackford C (2004) "Approaches in the design of a space plant cultivation facility for Arabidopsis thaliana." 34th ICES, SAE Technical Paper ICES 2004-01-2459.

Hoehn, A., Klaus, D. and Stodieck, L. (2004) “A Modular Suite of Hardware Enabling Space Flight Cell Culture Research” J. Gravitational Physiology 11(1): 39-50

Howard, H.N. and Klaus, D.M. (2004) “Antibiotic Effectiveness in Simulated Microgravity” (abstract) Gravitational and Space Biology Bulletin 18(1): p. 10

Klaus, D.M. (2004) “Bioastronautics in Aerospace Engineering Sciences” (abstract) Gravitational and Space Biology Bulletin 18(1): p.32

Klaus DM (2004) “Gravitational influence on biomolecular engineering processes.” Grav Space Biol Bul 17(2):51-65.

Klaus D, Chluda H, Ellis T, Fehring J, Howard H, Jairala J, Lloyd T, Matthews D, Morris K, Rowley K, Sauers C, Stephens T (2004) “Systems engineering evaluation of a Mars habitat design.” 34th ICES, SAE Technical Paper ICES 2004-01-2372.

Klaus, D., Benoit, M., Nelson, E. and Hammond, T. (2004) “Extracellular Mass Transport Considerations for Space Flight Research Concerning Suspended and Adherent in vitro Cell Cultures” J. Gravitational Physiology 11(1): 17-28

Manley, J.M., Benoit, M.R. and Klaus, D.M. (2004) “Non-invasive Measurement of the Population Density of E. coli Grown in Simulated Microgravity” (abstract) Gravitational and Space Biology Bulletin 18(1): p. 6

Medine GM, Zaikovskii V, Klabunde, KJ (2004) “Synthesis and adsorption properties of intimately intermingled mixed metal oxide nanoparticles.” J Mater Chem 14:757-763.

Miesse AM, Willey JS, Bateman TA (2004) “Potential role of proinflammatory cytokines in nerve damage related bone loss.”  Biomed Sci Instrumen 40:266-271.

Milstead JR, Simske SJ, Bateman TA (2004) “Comparison of skeletal disuse models in mice: spaceflight versus hindlimb suspension.”  J Bone Miner Res 21:M216. (abstract)

Milstead JR, Simske SJ, Bateman TA (2004) “Spaceflight and hindlimb suspension disuse models in mice.”  Biomed Sci Instrumen 40:105-110.

Pecaut MJ, Green LM, Bianski B, Jones TA, Nelson GA, Kostenuik PJ, Bateman TA, Morony, S, Stodieck, LS, Lacey, DL, Simske, SJ, Gridley, DS (2004) “Effects of spaceflight on hepatic gene expression in the C57BL/6 Mouse.” Grav Space Biol Bul 18:56. (abstract)

Seelig H-D, Klaus DM, Stodieck LS and Hoehn A (2004) “Non-contact measurement methods of detecting plant water deficit stress for space flight growth chamber application” 34th ICES, SAE Technical Paper ICES 2004-01-2455

Stroud, K.J. (2004) Mitigating Vestibular Disturbances During Spaceflight Using Virtual Reality Training and Reentry Vehicle Design Guidelines.  Doctoral Thesis, University of Colorado, Boulder

Thacker RE, Bateman TA (2004) “Differentiating the contribution of material and structural properties to changes in bone mechanical strength.”  J Bone Miner Res 1:SU234.  (abstract)

Yuan YY, Ferguson VL, Simske SJ, Bateman TA (2004) “Low dose administration of macrophage colony stimulating factor.”  Biomed Sci Instrumen 40:93-98.

2003

Benoit, M.R., D.M. Klaus and E.S. Nelson (2003) “Computational Modeling of Extracellular Mass Transport” (abstract) Gravitational and Space Biology Bulletin 17(1): p. 11

Clawson, J., Hoehn, A., Maute K. (2003) "Materials for transparent inflatable greenhouses", SAE-paper 2003-01-2326. International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada.

Dalton P, Gould M, Girten B, Stodieck LS, Bateman TA (2003) “Preventing annoyance from odors in spaceflight: a method for evaluating the sensory impact of rodent housing.”  J Appl Physiol 95:2113-2121.

Ferguson, VL, Ayers, RA, Bateman, TA, Simske, SJ  Bone development and age-related bone loss in male C57BL/6J mice.  Bone 33:387-398; 2003. 

Gridley, DS, Nelson, GA, Peters, LL, Kostenuik, PJ, Bateman, TA, Morony, S, Stodieck, LS, Lacey, DL, Simske, SJ, Pecaut, MJ  Effect of spaceflight on immunity in the C57BL/6 mouse, Part II: Activation, cytokines, erythrocytes, and platelets.  J Appl Physiol 94:2095-2103; 2003.

Harrison BC, Allen DL, Stodieck LS, Kostenuik PJ, Bateman TA, Morony, S, Leinwand, LA (2003) “Skeletal muscle adaptations to microgravity in the mouse.”  J Appl Physiol 95:2462-2470.

Hatfield, T.R. and Klaus, D.M. (2003): “Development of Quantitative Ultrasonic Physiological Measurement Technology for Space Flight Application” International Academy of Astronautics (IAA) Humans in Space Symposium, Banff, Alberta, May 2003

Hoehn, A., Clawson, J., Geissinger, T., Kalinowski, W., Pineau, J.,  Scovazzo, P. (2003): “Design, Testing and Operation of Porous Media for Dehumidification and Nutrient Delivery in Microgravity Plant Growth Systems”. SAE-paper 2003-01-2614, International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada. PC.

Hoehn, A., Clawson, J., Freeman, J., Genova, J., Gifford, K., Stodieck, L. (2003): “Thermal Design of a Spaceflight Plant Chamber Payload”. SAE-paper 2003-01-2583, International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada.

Hoehn, A., Sampson, M., Seelig, H., Stodieck, L., Heyenga, A.G. (2003): “Spaceflight Plant Science Integration, Testing and Functional/Compatibility Verification”. SAE-paper 2003-01-2480, International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada. PC.

Klaus, D.M. (2003) “Gravitational Influence on Biomolecular Engineering Proesses” (abstract) Gravitational and Space Biology Bulletin 17(1): p. 22. 

Miesse AM, Milstead JR, Bateman TA  (2003) “Comparing effects of trabecular bone using two nerve damage disuse models in mice: sciatic nerve crush and sciatic neurectomy.” Grav Space Biol Bul 17:62.  (abstract)

Milstead JR, Miesse AM, Kostenuik PJ, Morony, S, Ferguson, VL, Simske, SJ, Lacey, DL, Bateman, TA (2003) “MicroCT analysis demonstrates OPG mitigates loss of spaceflight osteopenia in proximal humerus of mice.” Grav Space Biol Bul 17:62.  (abstract)

Pecaut, MJ, Nelson, GA, Peters, LL, Kostenuik, PJ, Bateman, TA, Morony, S, Stodieck, LS,  Lacey, DL, Simske, SJ, Gridley, DS  Effect of spaceflight on immunity in the C57BL/6 mouse, Part I: Immune population distribution.  In press for: J Appl Physiol 94:2085-2094; 2003.

Prasad BLV, Stoeva SI, Sorensen CM, Zaikovski V, Klabunde KJ (2003) “Gold nanoparticles as catalysts for polymerization of alkylsilanes to siloxane nanowires, filaments, and tubes.” J Am Chem Soc, 125:10488-10489.

Ries, R. Bockstahler, S., Higgins, C.,  Atkinson, K., Lewandowski, S., Gjestvang, R., Frey, A.,  Clawson, J.,  Klaus, D. "RedThumb:  A Mars greenhouse design for the 2002 MarsPort engineering  design student competition", SAE-paper 2003-01-2676. International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada.

Simons ML, Thacker RE, Yuan Y, Bateman TA (2003) “Spaceflight-induced changes in tibial bone formation in the mouse.”  Grav Space Biol Bul 17:62.  (abstract)

Simske, SJ, Ferguson, VL, Bateman, TA  Mice and osteoporosis research. Pandalai, SG (ed.) Recent Research Developments in Biotechnology and Bioengineering vol. 5, ISBN 81-271-0011-0, Research Signpost, Kerala, India, pp. 97-127; 2003.

Stoeva S.I., Prasad BLV, Sitharaman U, Stoimenov P, Zaikovski V, Sorensen CM, Klabunde KJ (2003) “Face-Centered Cubic and Hexagonal Close-Packed Nanocrystal Superlattices of Gold Nanoparticles Prepared by Different Methods.” J Phys Chem B (invited paper for A. Henglein Special Issue), 107:7441-7448.

Stoimenov PK, Zaikovski V, Klabunde KJ; (2003). “Novel Halogen and Interhalogen Adducts of Nanoscale Magnesium Oxide.” J Am Chem Soc, 125:12907-12913.

Stroud, K.J., Harm, D.L. and Klaus, D.M. (2003): “Virtual Reality Training in Unfamiliar Environments: A Potential Countermeasure for Space Motion Sickness and Spatial Disorientation During Space Flight” 54th International Astronautical Congress (IAC), Bremen, Germany, October 2003

Stroud, K.J., Klaus, D.M. and Harm, D.L. (2003): “Applications of Vestibular System Response to Mission Risk Mitigation Factors and Spacecraft Design Requirements” SAE Technical Paper 2003-01-2535.

Thacker, RE, Yuan Y, Bateman TA (2003) “Mineral characterization of mouse bone after exposure to micro-gravity using Fourier transform infrared (FTIR) spectroscopy.”  Grav Space Biol Bul 17:62 (abstract)

Woodard, S., Goulart, C., Hoehn, A. (2003) "Performance of the STARS life sciences payload during benchtop testing  and mission simulations", SAE-paper 2003-01-2530. International Conference On Environmental Systems (ICES), July 2003, Vancouver, Canada.

2002

Bateman, TA, Morony, S, Ferguson, VL, Simske, SJ, Lacey, DL, Warmington, KS, Dunstan, CR, Stodieck, LS, Kostenuik, PJ  Spaceflight-induced changes in mouse bone and osteoprotegerin therapy.  Grav Space Biol Bul 16:30; 2002.  (abstract)

Brown, R., Klaus, D. and Todd, P. (2002): “Effects of space flight, clinorotation and centrifugation on the substrate utilization efficiency of E. coliMicrogravity Sci. and Tech XIII/4: 24-29

Ferguson, VL, Simske, SJ, Ayers, RA, Bateman, TA, Wang, HT, Bendele, A, Rich, B, Collins, D, Scherrer, J, Sennollo, R, Colagiovanni, DB (2002):  Effect of MPC-11 Myeloma and MPC-11 + IL-1ra Treatment on Mouse Bone Properties.  Bone 30:109-116

Ganta, R.R., Wilkerson, M.J., Cheng, C., Rokey, A.M., and Chapes, S.K. (2002) “Persistent Ehrlichia chaffeensis infection occurs in the absence of functional MHCII genes.” Infect. Immun. 70:380-388.

Girten, B, Hoopes, R, Steele, M, Bateman, TA  Effects of microgravity on oxidative and anti-oxidant enzymes in mouse hindlimb muscle.  Grav Space Biol Bul 16:38; 2002.  (abstract)

Gridley, DS, Nelson, GA, Peters, LL, Kostenuik, PJ, Bateman, TA, Morony, S, Stodiek, LS, Lacey, DL, Simske, SJ, Pecaut, MJ  Spaceflight and immunity in the mouse: Part II.  Grav Space Biol Bul 16:61; 2002. (abstract)

Goulart, C., Rupert, M., Woodard, S., Hoehn, A.  (2002) “Habitat Development in Support of Small Scale Biological & Biochemical Space Experiments.”   SAE Technical paper.  Presented at the International Conference On Environmental Systems, July, San Antonio, TX, USA. 

Harrison, BC, Allen, DL, Stodieck, LS, Kostenuik, PJ, Bateman, TA, Morony, S and Leinwand, LA  Micro-gravity exposure results in significant atrophy of murine skeletal muscle without alterations in myosin heavy chain gene expression.  Grav Space Biol Bul 16:20; 2002.  (abstract)

Hua, D.H., Tamura, M., Huang, X., Stephany, H.A., Helfrich, B.A., Perchellet, E.M., Sperfslage, B.J., Perchellet, J.P., Jiang, S., Kyle, D.E., Chiang, P.K. (2002) “Syntheses and bioactivities of substituted 9,10-dihydro-9,10- [1,2]benzenoanthra­cene-1,4,5,8-tetraones. Unusual reactivities with amines.” J Org Chem. 67: 2907- 2912.

Klaus, D.M. (2002): “Space Microbiology: Microgravity and Microorganisms” in The Encyclopedia of Environmental Microbiology, G. Britton (ed.), John Wiley & Sons, NY, pp. 2996-3004

Klessig, D.F., Kachroo, P.K., Slaymaker, D., Yoshioka, K., Navarre, D.A., Clark, D., Kumar, D., and Shah, J. (2002) “SA- and NO-mediated signaling in Plant Disease Resistance.” In: Biology of Plant-Microbe Interactions. Ed. S.A. Leong, C. Allen, and E.W. Triplet, IS-MPMI, St Paul, MN. Vol. 3, pp 78-82.

Lam, K.S., Gustavson, D.R., Pirnik, D.L., Pack, E., Bulanhagui, C., Mamber, S.W., Forenza, S., Stodieck, L.S. and Klaus, D.M. (2002): “The effect of space flight on the production of actinomycin D by Streptomyces plicatusJ. Industrial Microbiology and Biotechnology 29 (6): 299-302.

Maezawa, I., Hua, D.H, Shie, F., Alvord, E., Martin, G.M., and Jin, L.W. (2002) “Novel tricyclic pyrone compounds prevent intracellular A-beta-related cell death.” J. Neuropathol. Exp. Neurol. 61, 454, Abst. # 48.

Marchin, GL, A Eberth, P Stoimenov, K Nelson and K Klabunde.  (2002)  “Inactivation of the algal toxin microcystin LR by nanoparticles.”  Proc Ann Meet ASM Q-118  p. 398.

Owen, R.B., Zozulya, A.A., Benoit, M.R. and Klaus, D.M. (2002): “Microgravity materials and life sciences research applications of digital holography” J. Applied Optics 41: 3927-3935

Pecaut, MJ, Nelson, GA, Peters, LL, Kostenuik, PJ, Bateman, TA, Morony, S, Stodiek, LS, Lacey, DL, Simske, SJ, Gridley DS  Spaceflight and immunity in the mouse: Part I.  Grav Space Biol Bul 16:30; 2002.  (abstract)

Perchellet, E.M., Sperfslage, B.J., Wang, Y., Huang, X., Tamura, M., Hua, D.H., and  Perchellet, J.P. Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.  Anti-Cancer Drugs, 2002, 13, 567-581. 

Sharvelle, S. Silverstein, J. Supra, L., Finger, B. and Klaus, D. (2002) “Nitrite Accumulation in a Bioprocessor for Urine-Soap Waste” 32nd ICES SAE Technical Paper 2002-01-2353

Simmons, D., Benoit, M., Freeman, J., Genova, J and Hoehn, A. (2002) "Designing Fluid Handling Systems for Space Life Science Experimentation", SAE Technical Paper 2002-01-2281. Presented at the International Conference On Environmental Systems, July, San Antonio, TX, USA.

Simske, S.J., Bateman, T.A., Smith, E.E., Ferguson, V.L., and Chapes, S.K. (2002) “Effects of major histocompatibility complex class II knockout on mouse bone mechanical properties during development.” Proceed. Biomed. Sci. Instrum. 38:47-52.

Stoimenov, P., Klinger, R.L., Marchin, G.L., and Klabunde, K.J. (2002) “Metal oxide nanoparticles as bactericidal agents.” Langmuir. 18:6679-6686.

Wang, Y., Perchellet, E.M., Tamura, M., Hua, D.H., and Perchellet, J.P.   Induction of poly(ADP-ribose) polymerase cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines.  Cancer Letters (Shannon, Ireland), 2002, 188(1-2), 73-83. 

2001

Bateman, T.A., Dunstan, C.R., Lacey, D.L., Ferguson, V.L. and Simske, S.J. (2001) Osteoprotegerin ameliorates sciatic nerve crush induced bone loss.  J Orthoped Res. 19: 518-523

Chapes, S.K., Mosier, D.A., Wright, A.D., and Hart, M.L. (2001) “MHCII, Tlr4 and Nramp1genes control host pulmonary resistance against the opportunistic bacterium Pasteurella pneumotropica.” J. Leukoc. Biol. 69: 381-386.

Chapes, S.K., Wright, A.D., Beharka, A.A. (2001) “Superantigen activation of macrophages.”In: Staphylococcal Disease and Infection, eds., A.L. Honeyman, M. Bendinelli, H.Friedman, Kluwer Academic/Plenum. New York. July.

Ferguson, V.L., Hermann, L.K., Smith, E.E., Bateman, T.A., and Simske, S.J. (2001) “Effects of age and amylin treatment on long bones in growing and mature mice.” J Bone Miner Res. 16sup: S484.

Hua, D.H, McGill, J.W, Robinson, P.D., and Meyers, C.Y. (2001) “Crystal structure of tri-[1’-(phenylthio)-1-ferrocenyl]boroxin.” Acta Cryst. E57, 413-415.

Jin, L.W., Hua, D.H., Shie, F.S., Maezawa, I., Sopher, B., and Martin, G.M. (2001) “Novel Tricyclic Pyrone Compounds Prevent Intracellular Amyloid beta-induced Cell Death.” The Institute for the Study of Aging (ISOA). (In press).

Klaus, D and Jost, J. (2001): “Analysis of Gravity-Dependent and Independent Extracellular Mass Transport Phenomena” in Proceedings of the Conference on Microgravity Transport Processes in Fluid, Thermal, Materials and Biological Sciences II, S. S. Sadhal (ed.), United Engineering Foundation, UEF: MTP-01-70, pp. 527-532.

Klaus, D.M. (2001) “Clinostats and Bioreactors” Gravitational and Space Biology Bulletin 14(2): 55-64.

Klaus, D, Benoit, M, Bonomo, J, Bollich, J. Freeman, J, Stodieck, L, McClure, G and Lam, KS (2001): “Antibiotic Production in Space using an Automated Fed-Bioreactor System” in Proceedings of the AIAA Conference on ISS Utilization, AIAA-2001-4921.

Koper, O.B, Klabunde, J.S., Marchin, G.L., Klabunde, K.J., Stoimenov, P. and Bohra, L. (2001) “Nanoscale powders and formulations with biocidal activity toward spores and vegetative of Bacillus species, viruses and toxins.” Current Microbiology 44:49-55.

Perchellet, E.M., Sperfslage, B.J., Qabaja, G., Jones, G.B., Perchellet, J.P. (2001) “Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro.” Anti-Cancer Drugs. 12: 401-417.

Pineau, J., Kalinowski, B and Hoehn, A. (2001) “Autonomous Two-Phase Priming and Pressure Control System for Microgravity Porous Tube Hydroponics” KC-135 and Other Microgravity Simulations Summary Report, NASA Space and Life Sciences Directorate CR-208929: pp. 134-141

Ross, AB, Bateman, TA, Kostenuik, PJ, Lacey, DL, Dunstan, CR, Ferguson, VL, Simske, SJ  (2001) Effect of osteoprotegerin on the mechanical properties of rat bone.  J Mat Sci: Mat Med 12: 583-588. 

Perchellet, E.M., Sperfslage, B.J., McIlvain, C.J., Aligiannis, N., Pouli, N., Marakos, P., Skaltsounis, A-L., Perchellet, J.P. (2001) “Antileukemic activity of synthetic daunomycinone derivatives bearing modifications in the glycosidic moiety.” Anticancer Res. 21: 3957-3968.

Scovazzo, P., Illangasekare, T.H., Hoehn, A., and Todd, P. (2001) Modeling of two-phase flow in membranes and porous media in microgravity as applied to plant irrigation in space. Water Resources Res. 37(5): 1231-1243.

Stodieck, L., Hoehn, A., and Klaus, D.   (2001) “Commercial Space Life Sciences Research: Opportunities and Challenges on the International Space Station” in Proceedings of the AIAA Conference on ISS Utilization, AIAA-2001-4911.

Vellinger, J., Barton, K.W., Doyle, J.F., Wells, M.E., Todd, P. and Chapes, S.K. (2001) “Multiple robotic cell culture bioreactor systems for cell and tissue research in low gravity.” AIAA Paper 2001-5012, American Institute of Aeronautics and Astronautics Proceedings on International Space Station Utilization. Washington, DC.

Wang, B., Wu, M., Perchellet, E.M., McIlvain, C.J., Sperfslage, B.J., Huang, X., Tamura, M., Stephany, H.A., Hua, D.H., Perchellet, J.P. (2001) “A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.” Int J Oncology. 19: 1169-1178.

Wu, M., Wang, B., Perchellet, E.M., Sperfslage, B.J., Stephany, H.A., Hua, D.H., Perchellet, J.P. (2001) “Synthetic 1,4- anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.” Anti-Cancer Drugs. 12: 807-819.

2000

Ayers, R.A., Bateman, T.A. and Simske, S.J. (2000) “Porous NiTi as a material for bone engineering.”  LH Yahia (ed) Shape Memory Implants, Springer-Verlag, New York.

Bateman, TA, Dunstan, CR, Ferguson, VL, Lacey, DL, Ayers, RA, Simske, SJ (2000) “Osteoprotegerin mitigates tail suspension induced osteopenia.”  Bone, 26: 443-449.

Bateman, TA, Stodieck, LS, Kostenuik, PJ, Ferguson, VL, Simske, SJ  (2000) Use of Spaceflight and Spaceflight Simulation to Provide Evidence for Osteoprotegerin Treatment of Disuse Osteoporosis.  Space Tech Appl Int Forum ’00 2:580-581.

Chapes, S.K., Wright, A.D. and Beharka, A.A. (2000) “Superantigen activation of macrophages.” Staphylococcal Disease and Infection, Honeyman, A.L., Bendinelli, M. and Friedman, H. – Editors, Kluwer Academic/Plenum, New York.

Clawson, J.M., Hoehn, A., Stodieck, L.S., Todd, P., and Stoner, R.J.  (2000) “Re-examining aeroponics for spaceflight plant growth.”  Society of Automotive Engineers Technical Paper Series, No. 2000-01-2507, 30th International Conference on Environmental System, Toulouse, France; July 9-13.

Clawson, J.M., Hoehn A., Stodieck, L., Todd, P. and Cadogan, D.  (2000) “Optimizing the structural subsystem of the AG-Pod crop production unit.”  Society of Automotive Engineers Technical Paper Series, No. 2000-01-2477, 30th International Conference on Environmental System, Toulouse, France; July 9-13.

Ferguson, VL, Ayers, RA, Bateman, TA, Simske, SJ (2000) Development of endogenous osteoporosis in male C57BL/6J mice.  J Bone Miner Res 15sup: S461. 

Gifford, K.K.  (2000) "Linux at the University: In Space, on the Ground, and in the Classroom," Linux Journal, 77: pp. 56-70.

Hermann, LK, Ferguson, VL, Bateman, TA, Simske, SJ  (2000) Combined treatment effects of IGF-I and M-CSF on mouse bone composition, mechanical properties and quantitative histomorphometry.  J Bone Miner Res 15sup:S369. 

Heyenga, A.G.  Forsman, A. Stodieck, L.S., Hoehn, A. and Kliss, M. (2000) “Approaches in the Determination of Plant Nutrient Uptake and Distribution in Space Flight Conditions,” Advances in Space Research, 26(2): 299-302.

Heyenga A.G., Hoehn, A., Stodieck, L. and  Kliss, M. (2000), “The design of a mechanized seed sowing system for space flight application” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2506, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Hoehn A., Stodieck, L. Clawson, J., Robinson, E., Seelig, H., Heyenga, A.G., and Kliss, M.  (2000) “Atmosphere control of spaceflight plant growth chambers” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2232, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Hoehn, A., Scovazzo, P., Stodieck, L., Clawson, J., Kalinowski, W., Rakow, A. Simmons, D., Heyenga, A.G. and Kliss, M. (2000) “Microgravity Root Zone Hydration Systems” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2510, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Hua, D.H., Takasu, K., Huang, X., Millward, G.S., Chen, Y., Liu, L.Z. and Fan, J.M. (2000)  “Palladium-mediated ring closure reactions. Facile syntheses of enantiopure bicyclic and tricyclic alkenones.” Tetrahedron 56:7389-7398.

Khramtsov, N.V. and Upton, S.J. (2000) “Association of RNA polymerase complexes of the parasitic protozoan Cryptosporidium parvum with virus‑like particles: heterogeneous system.” J. Virol, 74(13): 5788‑5795.

Khramtsov, N.V., Chung, P.A., Dykstra, C.C., Griffiths, J.K., Morgan, U.N., Arrowood, M.J. and Upton, S.J. (2000) “Presence of dsRNAs in human and calf isolates of Cryptosporidium parvum.J. Parasitol, 86(2): 275‑282.

Klaus, D. (2000): “Commercial Microbial Research: From Spacelab to the International Space Station” in Proceedings from The Spacelab Accomplishments Forum. J. Emond (ed.), NASA/CP-2000-210332, pp. 223-238.

Kliss, M., Heyenga, A.G., Hoehn, A. and Stodieck, L.S.  (2000) “Recent Advances in Technologies Required for a Salad Machine” Advances in Space Research, 26(2): 263-269.

Kliss, M., Heyenga, A.G., Hoehn, A., and Stodieck,L.S. (2000) “Towards the development of a Salad Machine" Society of Automotive Engineers Technical Paper Series, No. 2000-01-2476, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Lindsay, D.S., Woods, K.M., Upton, S.J. and Blagburn, B.L. (2000) “Activity of decoquinate against Cryptosporidium parvum in cell cultures and neonatal mice.” Vet. Parasitol, 89: 307‑311.

Morgan, U.M., Xiao, L., Monis, P., Sulaiman, I., Pavlasek, I., Blagburn, B.L., Olsen, M., Upton, S.J, Khramtsov, N.K., Lal, A., Elliot, A. and Thompson, R.C.A. (2000) “Molecular and phylogenetic analysis of Cryptosporidium muris from various hosts.” Parasitology, 120(5): 457‑464.

Morgenthaler, George W. and Woodcock, Gordon R. (2000) “Implementing Settlement-Compatible Mars Transportation Architectures,” IAF/IAA-00-13.3.02, presented at the 51st International Astronautical Congress, Rio de Janeiro, Brazil, Oct.2-Oct.6, 2000. 

Morgenthaler, George W. and Clark, Ben C. (2000) “Robots for Human Missions to Mars:  The Fifth Application,” IAA-00-IAA-13.1.01, presented at the 51st International Astronautical Congress, Rio de Janeiro, Brazil, Oct.2-Oct.6, 2000.

Pecaut, MJ, Simske SJ, and Fleshner M. (2000): Spaceflight induces changes in splenocyte subpopulations: effectiveness of ground-based models. Am J Physiol Regulatory Integrative Comp Physiol 279: R2072-R2078.

Perchellet, E.M., Magill, M.J., Huang, X., Dalke, D.M., Hua, D.H., and Perchellet, J.P. (2000) “1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range than daunorubicin in vitro. Anti-Cancer Drugs, 11: 339-352.

Perchellet, Q.G., Perchellet, E.M., Jones, G.B., (2000) “Regioselective lactonization of naphthoquinones: synthesis and antitumoral activity of the WS-5995 antibiotics.” Tetrahedron Lett, 41: 3007-3010.

Supra, L.N., Finger, B.W., Reddig, M.A., MacKnight, A.K., Silverstein, J., Klaus, D.M., Urban, J.E. and Strayer, D.F. (2000) “Biological Wastewater Processor Experiment Definition” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2468, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Wells, B., Hoehn, A. and Levine, H.  (2000) “Collaborative development of a spaceflight experiment comparing two plant nutrient delivery systems” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2509, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Wessling, F.C., Stodieck, L.S., Hoehn, A., Woodard, S., and Thomas, S.  (2000) “Low temperature, low energy carrier (LoTec) and phase change materials (PCMS) for biological samples” Society of Automotive Engineers Technical Paper Series, No. 2000-01-2506, 30th International Conference on Environmental Systems, Toulouse, France; July 9-13.

Zhao, K., An, K., Fattaey, H. and Johnson, T. (2000) “CeReS-18, a Cell Regulatory Sialoglycopeptide, Inhibits Proliferation and Migration of Rat Vascular Smooth Muscle Cells.” Experimental Cell Research, 260: 181-188.

Zhu, G., Marchewka, M.J, Woods, K.M., Upton, S.J. and Keithly, J.S. (2000) “Molecular analysis of a type I fatty acid synthase in Cryptosporidium parvum.Mol. Biochem. Parasitol, 105(2): 253‑260.

1999

Ayers, R.A., Simske, S.J., Bateman, T.A., Petkus, A., Sachdeva, R.L.C., and Gyunter, V.E.  (1999): Effect of nitinol implant porosity on cranial bone ingrowth and apposition after 6 weeks.  J Biomed Mater Res.  45: 42-47.

Ayers, R.A., Wolford, L.M., Bateman, T.A., Ferguson, V.L., and Simske, S.J.  (1999): Quantification of bone ingrowth into porous block hydroxyapatite in humans.  J Biomed Mater Res.  47: 54-59.

Bateman, TA, Ayers, RA, Greenway, RB  (1999) An engineering evaluation of four fluid transfer devices for 384-well high throughput screening.  Lab Robotics and Automat 11:250-259. 

Bateman, TA, Lacey, DL, Ferguson, VL, Dunstan, CR, Ayers, RA, Simske, SJ  (1999) Comparison of osteoprotegerin, pamidronate and ibandronate in the treatment of suspension induced osteopenia.  J Bone Miner Res 14sup: S528. 

Bateman, TA, Kostenuik, PJ, Ferguson, VL, Ayers, RA, Simske, SJ  (1999) Osteoprotegerin treatment of tail suspension and sciatic nerve crush disuse osteopenia: comparison with bisphosphonates.  Grav Space Biol Bul 13:51. 

Brown, R.B. (1999) Effects of space flight, clinorotationand centrifugation on the growth and metabolism of Escherichia coli.  Doctoral Dissertation, University of Colorado, Boulder.

Chapes, S.K., Simske, S.J., Sonnenfeld, G., Miller, E.S., and Zimmerman, R.J.  (1999) Effects of spaceflight and PEG-IL-2 on rat physiological and immunological responses.  J. Appl. Physiol.  86: 2065-2076.

Chapes, S.K., Simske, S.J., Forsman, A.D., Bateman, T.A., and Zimmerman, R.J.  (1999) Effects of space flight and IGF-1 on immune function.  Adv. In Space Research.  23: 1955-1964.

Fattaey, H.K., Quinton, T.M., Zhao, K., He, F., Paulsen, Q. and Johnson, T.C.  (1999) CeReS-18 inhibits growth and induces apoptosis in human prostate cancer cells.  The Prostate.  38: 285-295.

Ferguson, VL, Bateman, TA, Lacey, DL, Ayers, RA, Dunstan, CR, Simske, SJ  (1999) Effect of osteoprotegerin on mechanical and material properties of maturing rat femora.  J Bone Miner Res 14sup:S440.

Ferguson, V.L., Greenberg, A.R., Bateman, T.A., Ayers, and R.A., Simske, S.J.  (1999) Effect of age and dietary restriction without nutritional supplementation on whole bone structural properties in C57BL/6J mice.  Biomed. Sci. Instrument.  35: 85-91.

Forsman, A.D., Herpich, A.R. and Chapes, S.K. (1999) “Improved soft-agar colony assay in a fluid processing apparatus.” In Vitro Cell and Developmental Biology, 35: 55-60.

Hoehn, A., Clawson, J.M., Heyenga, A.G., Scovazzo, P., Sterrett, K.S., Stodieck, L.S., Todd, P., and Kliss, M.H.   (1999)  Mass transport in a spaceflight plant growth chamber.  SAE 1998 Transactions/J. of Aerospace.  107(1).

Hoehn, A., Clawson, J.M., and Stodieck, L.S. (1999). “AG Pod - The Integration of Existing Technologies for Efficient, Affordable, Space Flight Agriculture“. Proceedings, ICES 1999, Denver, SAE paper 1999-01-2176.

Hoehn, A., Freeman, J.B., and Stodieck, L.S. (1999). “Incubator Designs for Space Flight Application - Optimization and Automation“. Proceedings, ICES 1999, Denver, SAE paper 1999-01-2177.

Hua, D.H., Chen, Y., Sin, H.S., Robinson, P.D., Meyers, C.Y., Perchellet, E.M., Perchellet, J.P., Chiang, P.K. and Biellmann, J.F. (1999) “6,7,8,9-Tetrahydro-3-methyl-1H-pyrano[4,3-b]quinoline-1-one.” Acta Cryst, C55: 1698-1701.

Hua, D.H., Chen, Y. and Millward, G.S. (1999) “N-Alkylidenesulfinamides.” Sulfur Reports, 21 (Suppl. 3): 211-239.

Kacena, M.A., Merrell, G.A., Manfredi, B., Smith, E.E., Klaus, D.M., and Todd, P.  (1999).  Bacterial growth in space flight: logistic growth curve parameters for Escherichia coli and Bacillus subtilis.  Appl. Microbiol. Biotechnol.  51: 229-234.

Kacena, M.A., Smith, E.E., and Todd, P.  (1999).  Autolysis of Escherichia coli and Bacillus subtilis cells in low gravity.  Appl. Microbiol. Biotechnol.  51: 229-234.

Klein, R.D., Geary, T.G., Gibson, A.S., Favreau, M.A., Winterrowd, C.A., Upton, S.J., Keithly, J.S., Zhu, G., Malmberg, R.L., Martinez, M.P. and Yarlett, N. (1999) “Reconsitution of a bacterial/plant polyamine biosynthesis pathway in Saccharomyces cerevisiae.Microbiology, 145: 301‑307.

Klement, B.J. and B.S. Spooner (1999) Mineralization and growth of cultured embryonic skeletal tissue in microgravity.  Bone 24:349-359.

Lindsay, D.S., Upton, S.J. and Dubey, J.P. (1999) “A structural study of the Neospora caninum oocyst.” Int. J. Parasitol, 29: 1521‑1533.

Monday, S., Vath, G., Ferens, W., Deobald, C., Rago, J., Gahr, P.J., Monie, D.D., Iandolo, J.J., Chapes, S.K., Jenkins, M., Davis, W.C., Ohlendorf, D., Schlievert, P. and Bohach, G.A. (1999) “Unique superantigen activity of staphylococcal exfoliative toxins.” J. Immunol, 162: 4550-4559.

Morgenthaler, George W. and Woodcock, Gordon R. (1999) “Applying Cost/Benefit Modeling to Evaluating Human Mars Exploration Architectures,” IAF-99-13.3.07, presented at the 50th International Astronautical Congress, Amsterdam, The Netherlands, Oct.4-Oct.8, 1999.

Morgenthaler, George W. and Khatib, Nader (1999) “Use of Remote Sensing Agricultural “Truth” Sites to Validate and Enhance Precision Agriculture Practices,” IAF-99-B.5.10, 50th International Astronautical congress, Amsterdam, The Netherlands, Oct. 4-8, 1999. 

Nesterenko, M.V., Woods, K.M. and Upton, S.J. (1999) “Receptor/ligand interactions between Cryptosporidium parvum and the surface of the host cell.” Biochimica et Biophysica Acta, 1454(2): 165‑173.

Perchellet, E.M., Ladesich, J.B., Magill, M.J., Chen, Y., Hua, D.H., and Perchellet, J.P. (1999) “Tricyclic pyrone analogs: a new synthetic class of bi-functional anti-cancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro, and the growth of solid tumors in vivo. Anti-Cancer Drugs, 10: 489-504.

Perchellet, E.M., Magill, M.J., Huang, X., Brantis, C.E., Hua, D.H., and Perchellet, J.P. (1999) “Triptycenes:  a novel synthetic class of bi-functional anti-cancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro. Anti-Cancer Drugs, 10: 749-766.

Perchellet, E.M., Ladesich, J.B., Collery, P., and Perchellet, J.P.  (1999).  Microtubule-disrupting effects of gallium chloride in vitro.  Anti-Cancer Drugs.  10: 477-488.

Perchellet, E.M., Ladesich, J.B., Magill, M.J., Chen, Y., Hua, D.H., and Perchellet, J.P.  (1999).  Tricyclic pyrone analogs: a new synthetic class of bi-functional anti-cancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro, and the growth of solid tumors in vivo.  Anti-Cancer Drugs.  10: 489-504.

Robinson, P.D., Beatty, A., Hua, D.H., Chen, Y., Meyers, C.Y., Perchellet, E.M., Ladesich, J.B., and Perchellet, J.P.  (1999).  Racemic 3-(3,4-dimethoxyphenyl)-5a,6,8,9-tetrahydro-1H,7H-pyrano[4,3-b][1]benzopyran-1-one, an active anti-tumor agent.  Acta Cryst.  C55: 1188-1190.

Simske, SJ, Bateman, TA, Ayers, RA, Dunstan, CR, Ferguson, VL, Lacey, DL (1999) Effect of osteoprotegerin, pamidronate and ibandronate on the sciatic nerve crush model for disuse osteoporosis in mice.  J Bone Miner Res 14sup:S523. 

Smith, J.D., L. A. Staehelin and P. Todd. (1999) Clover germination, early growth and root cap morphology in space and on a two-axis clinostat.  J. Plant Physiology 155: 543-550.

Todd, P., Doyle, J.F., Carter, P., Wachtel, H., Deuser, M.S., Vellinger, J.C., Cassanto, J.M., Alvarado, U., Sygusch, J., and Kent, T.B.  (1999) Magnetic space shuttle experiments.  J. Magnetism Magnetic Mat.  194: 96-101.

Todd, P, Pecaut MJ, and Fleshner M. (1999) Combined effects of space flight factors and radiation on humans. Mutation Res 430: 211-219.

Woods, K.M., Tilley, M., Iseli, A., Upton, S.J., Montelone, B.A. and Khramtsov, N.V. (1999) “Sequence of the gene encoding hsp90e from Cryptosporidium parvum.DNA Sequence, 10(4‑5): 339‑342.

Wright, A.D. and Chapes, S.K. (1999) “LPS Sensitivity in recombinant mice lacking functional alleles at MHCII, Lps and Nramp1 genes.” J. Endotoxin Res, 5: 297-308.

Wright, A.D. and Chapes, S.K. (1999) “Staphylococcal enterotoxin: a bound to MHC class I requires cross linking for the induction of TNF-α.” Cellular Immunol, 197: 129-135.

1998

Anderson, G.A., MacCallum, T.K., Poynter, J.E. and Klaus, D.M. (1998): “Autonomous Biological System – A Unique Method of Conducting Long Duration Space Flight Experiments for Pharmaceutical and Gravitational Biology Research”. in Space Technology and Applications International Forum (STAIF), CP 420, M.S. El-Genk (ed.), The American Institute of Physics, DOE CONF 980103, pp. 616-621.

Ayers, R.A., Bateman, T.A., Chapes, S.K., Ferguson, V.L., Simske, S.J. (1998)  “Effect of major histocompatability class II knockout on the mouse peripheral skeleton”.  Bone 23:S441. 

Ayers, R.A., Simske, S.J., Nunes, C.R., and Wolford, L.M. (1998):  "Long-Term Bone Ingrowth and Residual Microhardness of Porous Block Hyroxyapatite Implants in Humans". J Oral Maxillofac Surg. 56: 1297-1301.

Ayers, R.A., Simske, S.J., Nunes, C.R., and Wolford, L.M.  (1998)  Long-term ingrowth and residual microhardness of porous block hydroxyapatite implants in humans.  J Oral Maxilofac Surg.  56: 1297-1301.

Bateman, TA, Broz, JJ, Fleet, ML, Simske, SJ  (1998) Differing effects of two-week suspension on male and female mouse bone metabolism.  Biomed Sci Instrum 34:374-379. 

Bateman, T.A., Dunstan, C.R.,