University of Colorado, Boulder

Research in Bioengineering in the College of Engineering and Applied Science at CU Boulder

The following list is organized by Department, and includes links to research centers and programs and individual faculty members with research interests in biochemical and biomedical engineering.

Department of Aerospace Engineering Sciences

BioServe Space Technologies: A NASA-sponsored Research Partnership Center, works to develop new commercial uses for space in collaboration with industry. Approximately 30 faculty, staff and students conduct space-based research and development projects in the life sciences field with application to medical, pharmaceutical, biotechnology, agricultural and related industries. BioServe has conducted dozens of experiments on more than 20 space shuttle missions, including missions to the Russian Mir space station and regular space flight research on the International Space Station.

Alex Hoehn: Space flight experiment design for life sciences applications, including advanced life support systems and ecology, microgravity plant growth and biotechnology instrumentation.

David Klaus:  Microbial systems, microgravity simulation, spacesuits and spacecraft life support technologies

Kamran Mohseni: Vortex dynamics related to cardiac flows.

Louis Stodieck: Space life sciences research on plant and animal systems including cellular, whole plant and animal physiology. Emphasis on applications-oriented research.  Support development of space flight experimentation hardware.

Department of  Chemical and Biological Engineering

Biotechnology Training Program
 To provide graduate students with the training and orientation to combine basic and applied research, the University of Colorado at Boulder offers a pre-doctoral research training program, "Integrated Training for Biotechnology Leadership." The primary goals of this training program are for its graduates to have the skills and credentials necessary to undertake cross disciplinary research in modern industrial, academic, and governmental biotechnology research laboratories, and to serve as leaders in the continued advancement of beneficial applications of modern biology.

Industry/University Cooperative Research Center for Fundamentals and Application of Photopolymerization
The Research Center represents a collaboration of scientists from the University of Iowa, the University of Colorado, and industrial representatives. Photopolymerizations offer tremendous advantages over traditional thermal processing methods, including low energy requirements, spatial and temporal control of initiation, and high polymerization rates.

Center for Pharmaceutical Biotechnology
The Center for Pharmaceutical Biotechnology is a joint enterprise between the Department of Chemical and Biological Engineering and the School of Pharmaceutical Sciences at the CU Health Sciences Center. The center studies the molecular interactions that govern the stability of proteins in the presence of protective additives.

Kristi Anseth: Biomaterials, tissue engineering, photopolymerizations applied to medicine.

Christopher Bowman: Polymer chemistry, biomaterials, photopolymerizations applied to dentistry, tissue engineering and microfluidics.

Stephanie Bryant: Functional tissue engineering, photopolymerization, biomaterials.

Robert H. Davis: Biotechnology, complex fluids, membrane separations.

Ryan Gill:  Systems bioengineering: metabolic engineering and systems biology.

Dhinakar S. Kompala: Recombinant mammalian cell cultures,  metabolic pathway engineering,  tissue engineering.

Melissa Mahoney: Novel drug delivery and tissue engineering strategies to promote regeneration in the central nervous system.

W. Fred Ramirez: Optimal control and  identification of chemical, biochemical, and energy recovery processes.

Theodore Randolph: Supercritical fluid engineering, protein-solvent interactions.

Jeff Stansbury: Dental and biomedical polymeric materials, hybrid materials, photopolymerization processes, cross- linked  network polymers, hydrogels for biomaterial applications, polymerization with minimal stress development, combinatorial approaches to biomaterials development.

Department of Civil, Environmental and Architectural Engineering

Angela Bielefeldt: Biological treatment of hazardous organic compounds, subsurface bioremediation, biological wastewater treatment.

Mark Hernandez: Biological waste treatment processes, subsurface bioremediation, microbiology of aerosols.

Joe Ryan: Contaminant fate and transport in natural waters, colloid and biocolloids transport.

JoAnn Silverstein: Biological treatment processes for wastewater and water, bioremediation of acid mine drainage, water recycling in space.

R. Scott Summers: Drinking water quality and treatment, natural organic matter, disinfection by-products, membrane processes.

Department of Electrical  and Computer Engineering

Biomedical Engineering in ECE: Although the interdiscipline of bioengineering generally involves many facets of electrical and computer engineering, our current research is focused in three areas: (1) bioelectromagnetics and ultrasonics, which involve the use of electromagnetic and ultrasonic fields to probe biological function as well as to develop useful diagnostics and therapeutic instruments; (2) neurobiological engineering, in which we endeavor to explore brain function using bioelectrical concepts and techniques as well as aiding the development of advanced computer and "synthetically intelligent" systems; and (3) biomedical instrumentation for therapeutic testing in outer space.

Frank Barnes:   Biomedical telecommunications, bioelectromagnetics and optics, biopsy technology.

Francois Meyer: Medical imaging, motion analysis, cardiac image sequences, analysis of functional MRI sequences, and diverse applications of wavelets to signal and image processing.

Richard Mihran: Optical and electrical biosensors, electrophysiology, bio-instrumentation.

 Lucy Pao: Biomedical applications of robotics.

Melinda Piket-May: Approaching electromagnetic interaction with biological tissue using finite difference models.

Howard Wachtel: Intersections of electrophysiology, biophysics and neurosciences; bioeffects of electromagnetic fields; health implications of power line and high density traffic corridors.

Bart J. Van Zeghbroeck: Development of single molecule DNA sequencing using a nano-scale silicon chip.

Department of Mechanical Engineering

In addition to the topics listed below, ME is host to a developing research center: MicroElectronic Devices In Cardiovascular Applications (MEDICA).

Victor Bright: MEDICA, smart stents, microbiosensors and actuators.

Lawrence E. Carlson: Design and analysis of upper-limb prostheses; rehabilitation engineering.

Martin Dunn:  Mechanical and physical behavior of materials, with emphasis on heterogeneous materials and interface fracture, constitutive behavior of biomaterials, as influenced by microstructure at multiple scales, and failure of biomaterials and biological structures, especially at interfaces.

Ginger Ferguson: Nano-scale characterization of materials, related mech/material properties to bio functions of tissue. Multi-scale structure-property-function relationships for biological tissues. Study aging, unloading, disease and genetics for musculoskeletal system.

Alan R. Greenberg: Biomaterials/biomechanics; composite materials; characteristics of polymeric membranes and thin-films; thermal analysis techniques.

Jean R. Hertzberg: Vortex dominated fluid dynamics with applications to combustion and cardiopulmonary flows.

Shelly Miller: Indoor air quality, engineering controls for airborne pollutants, bioaerosols including allergens and bacteria.

Wei Tan: Research on cardiovascular bioengineering; bioMEMS; cell and tissue engineering biomaterials.

Robin Shandas: Cardiovascular fluid dynamics and biomedical devices.

Additional Bioengineering at CU Boulder

Gregory Beylkin, Applied Math:  Fast numerical algorithms, imaging and applied inverse problems, ab initio quantum chemistry

Tom Maneuffel: Numerical solution of partial differential equations, including CFD, electromagnetics and particle transport. Numerical linear algebra, including iterative methods for large sparse  linear systems, multigrid and algebraic multigrid methods.

Steve McCormick, Applied Math: Multilevel methods, partial differential equations, integral equations, computational fluid dynamics, adaptive mesh refinement methods, iterative schemes in general, least squares problems, eigenvalue problems, image reconstruction, human organ simulation, math software, vector and parallel supercomputing, inverse problems, particle transport, structural analysis, plasma physics, and combustion.

Kenneth Douglas, Physics:  Nanotechnology, using an inter-disciplinary approach incorporating elements of biology, chemistry, and materials science.

Roger M. Enoka, Ph.D., Department of Kinesiology and Applied Physiology: The neuromuscular mechanisms that mediate acute (arousal, muscle fatigue) and chronic (aging, gender, immobilization, strength training) adaptations in response to physical activity.

Bradley Palmer, Department of Kinesiology and Applies Physiology: Mathematical and computer modeling of calcium ion regulation and contraction dynamics of isolated cardiac myocytes.

Steve Schmidt,EPOB: Microbiology.

Jon Sauer,Interdisciplinary Telecommunications Program (ITP):
Ultrafast data transmission, ultrafast logic for computing (200GHz), fundamental physics using soliton-soliton interaction in fibers, development of single-molecule DNA sequencing using a nano-scale silicon chip.

Deborah Wuttke, Department of Chemistry and Biochemistry: Protein structure, protein folding, and molecular recognition.


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