Research in Bioengineering in the
College of Engineering and Applied Science at CU Boulder
The following list is organized by Department, and includes
links to research centers and programs and individual faculty
members with research interests in biochemical and biomedical
engineering.
Department of Aerospace
Engineering Sciences
BioServe Space Technologies: A NASA-sponsored Research Partnership Center,
works to develop new commercial uses for space in collaboration with
industry. Approximately 30 faculty, staff and students conduct space-based
research and development projects in the life sciences field with
application to medical, pharmaceutical, biotechnology, agricultural and
related industries. BioServe has conducted dozens of experiments on more
than 20 space shuttle missions, including missions to the Russian Mir
space station and regular space flight research on the International Space
Station.
Alex Hoehn:
Space flight experiment design for life sciences applications,
including advanced life support systems and ecology, microgravity
plant growth and biotechnology instrumentation.
David Klaus:
Microbial systems, microgravity simulation, spacesuits and spacecraft life support technologies
Kamran
Mohseni: Vortex dynamics related to cardiac flows.
Louis
Stodieck: Space life sciences research on plant and
animal systems including cellular, whole plant and animal
physiology. Emphasis on
applications-oriented research. Support development of space
flight experimentation hardware.
Department of
Chemical and Biological
Engineering
Biotechnology Training Program
To provide graduate students with the training and orientation to
combine basic and applied research, the University of Colorado at
Boulder offers a pre-doctoral research training program,
"Integrated Training for Biotechnology Leadership." The primary
goals of this training program are for its graduates to have the
skills and credentials necessary to undertake cross disciplinary
research in modern industrial, academic, and governmental
biotechnology research laboratories, and to serve as leaders in
the continued advancement of beneficial applications of modern
biology.
Industry/University Cooperative Research
Center for Fundamentals and Application of Photopolymerization
The Research Center represents a collaboration of scientists from the University of Iowa, the University of Colorado,
and industrial representatives. Photopolymerizations offer tremendous advantages over traditional thermal processing methods,
including low energy requirements, spatial and temporal control of initiation, and high polymerization rates.
Center for Pharmaceutical Biotechnology
The Center for Pharmaceutical Biotechnology is a joint enterprise
between the Department of Chemical and Biological Engineering and
the School of Pharmaceutical Sciences at the CU Health Sciences
Center. The center studies the molecular interactions that govern
the stability of proteins in the presence of protective additives.
Kristi Anseth: Biomaterials, tissue engineering,
photopolymerizations applied to medicine.
Christopher Bowman: Polymer chemistry, biomaterials,
photopolymerizations applied to dentistry, tissue engineering and
microfluidics.
Stephanie Bryant: Functional tissue engineering, photopolymerization, biomaterials.
Robert H. Davis: Biotechnology, complex fluids, membrane
separations.
Ryan Gill: Systems bioengineering: metabolic engineering
and systems biology.
Dhinakar S.
Kompala: Recombinant
mammalian cell cultures,
metabolic pathway engineering,
tissue engineering.
Melissa Mahoney: Novel drug delivery and tissue engineering strategies to promote regeneration in the central nervous system.
W. Fred Ramirez: Optimal control and identification of
chemical, biochemical, and energy recovery processes.
Theodore Randolph: Supercritical fluid engineering,
protein-solvent interactions.
Jeff Stansbury: Dental and biomedical polymeric
materials, hybrid materials, photopolymerization processes, cross-
linked network polymers, hydrogels for biomaterial applications,
polymerization with minimal stress development, combinatorial
approaches to biomaterials development.
Department of Civil, Environmental and Architectural
Engineering
Angela
Bielefeldt: Biological treatment of hazardous organic
compounds, subsurface bioremediation, biological wastewater
treatment.
Mark
Hernandez: Biological waste treatment processes,
subsurface bioremediation, microbiology of aerosols.
Joe Ryan: Contaminant fate and transport in natural
waters, colloid and biocolloids transport.
JoAnn
Silverstein: Biological treatment processes for wastewater
and water, bioremediation of acid mine drainage, water recycling
in space.
R. Scott Summers:
Drinking water quality and treatment, natural organic matter,
disinfection by-products, membrane processes.
Department of Electrical and Computer Engineering
Biomedical Engineering in ECE: Although the
interdiscipline of bioengineering generally involves many facets
of electrical and computer engineering, our current research is
focused in three areas: (1) bioelectromagnetics and ultrasonics,
which involve the use of electromagnetic and ultrasonic fields to
probe biological function as well as to develop useful diagnostics
and therapeutic instruments; (2) neurobiological engineering, in
which we endeavor to explore brain function using bioelectrical
concepts and techniques as well as aiding the development of
advanced computer and "synthetically intelligent" systems; and (3)
biomedical instrumentation for therapeutic testing in outer space.
Frank Barnes: Biomedical telecommunications,
bioelectromagnetics and optics, biopsy technology.
Francois Meyer: Medical imaging, motion analysis, cardiac
image sequences, analysis of functional MRI sequences, and diverse
applications of wavelets to signal and image processing.
Richard Mihran: Optical and electrical biosensors,
electrophysiology, bio-instrumentation.
Lucy
Pao: Biomedical applications of robotics.
Melinda Piket-May: Approaching electromagnetic interaction
with biological tissue using finite difference models.
Howard Wachtel: Intersections of electrophysiology,
biophysics and neurosciences; bioeffects of electromagnetic
fields; health implications of power line and high density traffic
corridors.
Bart J.
Van Zeghbroeck: Development of single molecule DNA
sequencing using a nano-scale silicon chip.
Department of Mechanical Engineering
In addition to the topics listed below, ME is host to a
developing research center:
MicroElectronic Devices
In Cardiovascular Applications (MEDICA).
Victor Bright: MEDICA, smart stents, microbiosensors and
actuators.
Lawrence E.
Carlson: Design and analysis of upper-limb prostheses;
rehabilitation engineering.
Martin
Dunn: Mechanical and physical behavior of materials, with
emphasis on heterogeneous materials and interface fracture,
constitutive behavior of biomaterials, as influenced by
microstructure at multiple scales, and failure of biomaterials and
biological structures, especially at interfaces.
Ginger Ferguson: Nano-scale characterization of materials, related mech/material properties to bio functions of tissue. Multi-scale structure-property-function relationships for biological tissues. Study aging, unloading, disease and genetics for musculoskeletal system.
Alan R. Greenberg: Biomaterials/biomechanics; composite
materials; characteristics of polymeric membranes and thin-films;
thermal analysis techniques.
Jean R. Hertzberg: Vortex
dominated fluid dynamics with applications to combustion and
cardiopulmonary flows.
Shelly Miller:
Indoor air quality, engineering controls for airborne pollutants,
bioaerosols including allergens and bacteria.
Wei Tan: Research on cardiovascular bioengineering; bioMEMS; cell and tissue engineering biomaterials.
Robin Shandas:
Cardiovascular fluid dynamics and biomedical devices.
Additional Bioengineering at CU Boulder
Gregory Beylkin, Applied Math: Fast numerical algorithms,
imaging and applied inverse problems, ab initio quantum chemistry
Tom
Maneuffel: Numerical solution of partial differential
equations, including CFD, electromagnetics and particle transport.
Numerical linear algebra, including iterative methods for large
sparse linear systems, multigrid and algebraic multigrid methods.
Steve
McCormick, Applied Math: Multilevel methods, partial
differential equations, integral equations, computational fluid
dynamics, adaptive mesh refinement methods, iterative schemes in
general, least squares problems, eigenvalue problems, image
reconstruction, human organ simulation, math software, vector and
parallel supercomputing, inverse problems, particle transport,
structural analysis, plasma physics, and combustion.
Kenneth Douglas,
Physics: Nanotechnology, using an inter-disciplinary
approach incorporating elements of biology, chemistry, and
materials science.
Roger M. Enoka, Ph.D.,
Department of Kinesiology and Applied Physiology: The
neuromuscular mechanisms that mediate acute (arousal, muscle
fatigue) and chronic (aging, gender, immobilization, strength
training) adaptations in response to physical activity.
Bradley Palmer,
Department of Kinesiology and Applies Physiology:
Mathematical and computer modeling of calcium ion regulation and
contraction dynamics of isolated cardiac myocytes.
Steve Schmidt,EPOB:
Microbiology.
Jon
Sauer,Interdisciplinary
Telecommunications Program (ITP):
Ultrafast data transmission, ultrafast logic for computing
(200GHz), fundamental physics using soliton-soliton interaction in
fibers, development of single-molecule DNA sequencing using a nano-scale
silicon chip.
Deborah Wuttke,
Department of Chemistry and Biochemistry: Protein
structure, protein folding, and molecular recognition.
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