Volunteer for Diabetes Research!

From: Administrative E-Memo (memofrom@Colorado.EDU)
Date: Wed Sep 02 2009 - 19:32:30 MDT

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    Date: Wed, 2 Sep 2009 19:32:30 -0600 (MDT)
From: Administrative E-Memo <memofrom@Colorado.EDU>
Subject: Volunteer for Diabetes Research!

    TO: Boulder Campus Teaching & Research Faculty, Staff,
             Deans, Directors, Dept Chairs, System Administration

    FROM: Endocrinology, Metabolism, and Diabetes

    SENDER: Devon Hunerdosse

    DATE: September 3, 2009

    SUBJECT: Volunteer for Diabetes Research!

    Subjects needed for an exercise metabolism research study

    Are you a man or woman aged 30-50 with or without Type II Diabetes who is
    interested in being involved in a research project? We are looking for
    volunteers to participate in a metabolism study investigating how fat stored
    in your muscle affects insulin activity.

    Exclusions: You cannot participate if you: smoke, have hyperlipidemia, or
    have been told by your doctor not to exercise. Diabetic subjects must be
    diagnosed <10 years ago, and be treated for diabetes using diet and
    exercise, and/or sulfonylureas, and/or acarbose only.

    Two different preliminary assessments will include:

    --body fat content measurements

    --maximal exercise capacity (VO2max)

    --heart rhythm

    --resting metabolic rate

    --glucose tolerance & insulin sensitivity testing

    --blood tests

    --health and physical examination performed by a physician

    Volunteers will complete one metabolic study day following a 12 hour fast,
    where you will lie quietly for 4 hours, exercise for 1.5 hours at an easy to
    moderate intensity (45% of maximal capacity), and lie quietly again after
    exercise for 2 hours. All 3 visits will be performed at the Clinical
    Translational Research Center on the Anschutz Medical Campus in Aurora.

    For the metabolic study day, the following will occur:

    --Diet will be controlled for 3 days before the study day

    --During the study day:

       - Infusion of naturally occurring tracer of carbohydrate and fat through
         an intravenous catheter

       - Blood sampling from a catheter placed in a hand vein

       - 3 muscle biopsies

       - 1.5 hours of exercise at 45% of maximal capacity

    Compensation will be provided.

    P.I. Dr. Bryan Bergman, COMIRB # 03-398, approved 7/05/07

    Please call Devon at 303-724-3968 for more information about this study.

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