From: Administrative E-Memo (memofrom@Colorado.EDU)
Date: Wed Sep 02 2009 - 19:32:30 MDT
Date: Wed, 2 Sep 2009 19:32:30 -0600 (MDT) From: Administrative E-Memo <memofrom@Colorado.EDU> Subject: Volunteer for Diabetes Research!
TO: Boulder Campus Teaching & Research Faculty, Staff,
Deans, Directors, Dept Chairs, System Administration
FROM: Endocrinology, Metabolism, and Diabetes
SENDER: Devon Hunerdosse
DATE: September 3, 2009
SUBJECT: Volunteer for Diabetes Research!
Subjects needed for an exercise metabolism research study
Are you a man or woman aged 30-50 with or without Type II Diabetes who is
interested in being involved in a research project? We are looking for
volunteers to participate in a metabolism study investigating how fat stored
in your muscle affects insulin activity.
Exclusions: You cannot participate if you: smoke, have hyperlipidemia, or
have been told by your doctor not to exercise. Diabetic subjects must be
diagnosed <10 years ago, and be treated for diabetes using diet and
exercise, and/or sulfonylureas, and/or acarbose only.
Two different preliminary assessments will include:
--body fat content measurements
--maximal exercise capacity (VO2max)
--resting metabolic rate
--glucose tolerance & insulin sensitivity testing
--health and physical examination performed by a physician
Volunteers will complete one metabolic study day following a 12 hour fast,
where you will lie quietly for 4 hours, exercise for 1.5 hours at an easy to
moderate intensity (45% of maximal capacity), and lie quietly again after
exercise for 2 hours. All 3 visits will be performed at the Clinical
Translational Research Center on the Anschutz Medical Campus in Aurora.
For the metabolic study day, the following will occur:
--Diet will be controlled for 3 days before the study day
--During the study day:
- Infusion of naturally occurring tracer of carbohydrate and fat through
an intravenous catheter
- Blood sampling from a catheter placed in a hand vein
- 3 muscle biopsies
- 1.5 hours of exercise at 45% of maximal capacity
Compensation will be provided.
P.I. Dr. Bryan Bergman, COMIRB # 03-398, approved 7/05/07
Please call Devon at 303-724-3968 for more information about this study.
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