Publications
Publications:
24. McCombs, J.E. and Palmer, A.E. Measuring calcium signaling with Genetically Encoded Calcium Indicators, submitted
23. Astori, S., Wallace, D.J., Borgloh, S.M.z.A., Yang, Y., Bausen, M., Kugler, S., Palmer, A.E., Tsien, R.Y., Sprengel, R., Kerr, J.N.D., Denk, W., and Hasan, M.T. (2008). Detection of Single Action Potentials in vitro and in vivo with a Genetically-encoded Activity Sensor, D3cpv. Nature Methods, Advanced online publication, nmeth.1242.pdf
22. VanEngelenburg, S.B. and Palmer, A.E., Quantitation of Real-Time Salmonella effector Type-Three Secretion Kinetics Using the Small Molecule Fluorophore FlAsH, Chemistry & Biology, 2008, 15(6): 619-628 Chem & Biol 2008.pdf Chem & Biol Supporting Info.pdf
21. Xu, C., Xu, W., Palmer, A.E., and Reed, J.C., BI-1 regulates Endoplasmic reticulum Ca2+ downstream of Bcl-2-family proteins, Journal Biol. Chem., 2008, 283(17): 11477-11484 JBC 2008.pdf
20. VanEngelenburg, S.B. and Palmer, A.E., Fluorescent sensors of protein function, Current Opinion Chemical Biol., 2008, 12(1): 60-65 Current Opinion 2008.pdf
19. Palmer, A.E. and Tsien, R. Y. Measuring Calcium Signaling Using Genetically Targetable Fluorescent Indicators, Nature Protocols, 2006, (2006), 1(2): 1-9 Nature Protocols 2006.pdf
18. Palmer A, E., Giacomello, M., Kortemme, T., Hires, S. A., Lev-Ram, V., Baker, D., Tsien R. Y., Ca2+ indicators based on computationally-redesigned calmodulin-peptide pairs, Chemistry and Biology, 2006, 13: 521-530 Chem & Biol 2006.pdf
17. Duman, J. G., Chen, L., Palmer A. E., Hille, B., Contributions of intracellular compartments to calcium dynamics: Implicating an acidic store, Traffic, 2006, 7: 859-872 Traffic 2006.pdf
16. Qunitanar, L. Yoon, J., Aznar, C.P., Palmer, A. E., Andersson, K. K., Britt, R. D., Solomon, E. I. Spectroscopic and electronic structure studies of the trinuclear Cu cluster active site of the multicopper oxidase laccase: nature of its coordination unsaturation, J. Am. Chem. Soc., 2005, 127(40):13832-13845 JACS 2005.pdf
15. Palmer, A. E., Jin, C, Reed, J. C., Tsien, R. Y., Bcl-2 mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor, Proc. Natl. Acad. Sci., 2004, 101:50, 17404-17409 PNAS 2004.pdf
* This work was highlighted in the following journals:
BioTechniques, 2005, 38:1, p1; Nature Reviews Molecular Cell Biology, 2005, 6, p92
14. Shaner, N.C., Campbell, R.E., Steinbach, P.A., Giepmans, B.N.G., Palmer, A.E., Tsien, R.Y. Improved monomeric red, orange, and yellow fluorescent proteins derived from Discoma red fluorescent protein, Nature Biotechnology, 2004, 22, 1567-1572 Nature Biotech 2004.pdf
13. Andersson, K.K., Schmidt, P.P., Katterle, B., Strand, K., Palmer, A.E., Lee, S.-K., Solomon, E.I., Graslund, A., Barra, A.-L. Examples of high frequency EPR studies in bioinorganic chemistry, J. Biol. Inorg. Chem., 2003, 8, 235-247 JBIC 2003.pdf
12. Palmer, A.E., Szilagyi, R.K., Cherry, J.R., Jones, A., Xu, F., Solomon, E.I. Spectroscopic characterization of the Leu513His variant of fungal laccase: effect of increased axial ligand interaction on the geometric and electronic structure of the Type 1 Cu site Inorg. Chem., 2003, 42, 4006-4017 Inorg Chem 2003.pdf
11. Campbell, R.E., Tour, O., Palmer, A.E., Steinbach, P.A., Baird, G. S., Zacharias, D.A., Tsien, R.Y. A Monomeric Red Fluorescent Protein Proc. Natl. Acad. Sci., 2002, 99, 7877-7882 Nature Biotech 2002.pdf
10. Palmer, A.E., Quintanar, L., Severance, S., Wang, T.-P., Kosman, D. J., and Solomon, E.I. Spectroscopic characterization and O2 reactivity of the trinuclear Cu cluster of mutants of the multicopper oxidase Fet3p, Biochemistry, 2002, 41, 6438-6448 Biochemistry 2002.pdf
9. Palmer, A.E., Lee, S.K., Solomon E. I. Decay of the Peroxide Intermediate in Laccase: Reductive Cleavage of the O-O Bond. J. Am. Chem. Soc. 2001, 123, 6591-6599 JACS 2001.pdf
8. Solomon, E.I., Chen, P., Lee, S.K., Metz, M., Palmer, A.E., Oxygen binding, activation, and reduction to water by Cu proteins, Angew. Chemie Int. Ed., 2001, 40:24, 4570-4590 Angewante 2001.pdf
7. Machonkin, T.E., Quintanar, L., Palmer, A.E., Hassett, R.F., Severance, S., Kosman, D.J., Solomon, E.I. Spectroscopic Characterization of FET3p, a new member of the multicopper oxidase family. J. Am. Chem. Soc., 2001, 123, 5507-5517 livepage.apple.com JACS 2001 (2).pdf
6. Palmer, A.E., Randall, D.W., Xu, F., Solomon, E.I. Spectroscopic studies and electronic structure description of the high potential type 1 copper site in fungal laccase: Insight into the effect of the axial ligand. J. Am. Chem. Soc. 1999, 121, 7138-7149 JACS 1999.PDF
5. Xu, F., Palmer, A.E., Yaver, D.S., Berka, R.M., Gambetta, G.A., Brown, S.H., Solomon, E.I. Targeted Mutations in a Trametes villosa laccase: axial perturbations of the T1 copper. J. Biol.Chem. 1999, 274, 12372-12375 JBC 1999.pdf
4. Wilcox, D.E., Bennett, L.L., Cox, E.H., Haleblian, G., Hill, B.T., Kowack, E.P., Liu, X., Merkel, J.S., Palmer, A.E., Posewitz, M.C., Roy, J.F., Wetterhahn, K.E. Interaction of Metallothionein with Carcinogenic Metals Ni(II), Cr(VI), and As(III). In: Metallothionein IV. Ed: Klassen, C.D. 1999, Birkhauser: Basel, p 585-594
3. Solomon, E.I., Palmer, A.E., Sundaram, U.M., Machonkin, T.E. Spectroscopic Studies of O2 Intermediates in Copper Proteins: Electronic Structure Contributions to Function in Bioinorganic Chemistry. In: Spectroscopic Methods in Bioinorganic Chemistry. Eds: Solomon, E.I. and Hodgson, K.O. 1998, ACS: Washington, D.C., p 423-452
2. Xu, F., Berka, R.M., Wahleithner, J.A., Nelson, B.A., Shuster, J.R., Brown, S.H., Palmer, A.E., Solomon, E.I. Site directed mutations in fungal laccase: effect on redox potential, activity, and pH profile. Biochemical J. 1998, 334, 63-70
1. Bobilya, D. J., D’Amour, K., Palmer, A., Skeffington, C., Therrien, N., Tibaduiza, E. C. Isolation and cultivation of porcine brain capillary endothelial cells as an in vitro model of the blood-brain barrier. Methods in Cell Science 1995, 17, 25-32