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Recent
Publications
[1990-1999] | [2000] | [2001] | [2002] | [2003] | [2004] | [2005] | [2006] | [2007] | [2008]
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2011
P.S. Hume and K.S.
Anseth, "Polymerizable
Superoxide Dismutase Mimic
Protects Cells Encapsulated in
Poly(ethylene glycol) Hydrogels
from Reactive Oxygen
Species-Mediated Damage," Journal
of Biomedical Materials
Research Part A, 99A
(1), 29-37 (2011).
P.S. Hume, C.N. Bowman,
and K.S. Anseth,
"Functionalized PEG Hydrogels
Through Reactive Dip-Coating for
the Formation of Immunoactive
Barriers," Biomaterials,
32 (26), 6204-6212 (2011).
B.J. Berron, L.M.
Johnson, X. Ba, J.D. McCall,
N.J. Alvey, K.S.
Anseth, and C.N.
Bowman, "Glucose
Oxidase-Mediated Polymerization
as a Platform for Dual-Mode
Signal Amplification and
Biodetection," Biotechnology
and Bioengineering, 108
(7), 1521-1528 (2011).
S.B. Anderson, C.C. Lin,
D.V. Kuntzler, and K.S.
Anseth, "The
Performance of Human Mesenchymal
Stems Cells Encapsulated in
Cell-Degradable Polymer-Peptide
Hydrogels," Biomaterials,
32 (14), 3564-3574 (2011).
B.D. Fairbanks, S.P.
Singh, C.N. Bowman, and K.S.
Anseth,
"Photodegradable, Photoadaptable
Hydrogels via Radical-Mediated
Disulfide Fragmentation
Reaction," Macromolecules,
44 (8), 2444-2450 (2011).
E.A. Sims, C.A.
DeForest, and K.S.
Anseth, "A Mild,
Large-Scale Synthesis of
1,3-Cyclooctanedione: Expanding
Access to Difluorinated
Cyclooctyne for Copper-Free
Click Chemistry," Tetrahedron
Letters, 52 (16),
1871-1873 (2011).
C.C. Lin and K.S.
Anseth, "Cell-Cell
Communication Mimicry with
Poly(ethylene glycol) Hydrogels
for Enchancing Beta-Cell
Function," PNAS,
108 (16), 6380-6385 (2011).
J.D. McCall, C.C. Lin,
C.J., and K.S.
Anseth, "Affinity
Peptides Protect Transforming
Growth Factor Beta During
Encapsulation in Poly(ethylene
glycol) Hydrogels," Biomacromolecules,
12 (4), 1051-1057 (2011).
B.J. Adzima, Y. Tao,
C.J. Kloxin, C.A. DeForest, K.S.
Anseth, and C.N.
Bowman, "Spatial and Temporal
Control of the Alkyne-Azide
Cycloaddition by Photoinitiated
Cu(II) Reduction," Nature
Chemistry, 3 (3),
256-259 (2011).
R.K. Sivamani, M.P.
Schwartz, K.S. Anseth and
R.R. Isseroff, “Keratinocyte
Proximity and Contact can Play a
Significant Role in Determining
Mesenchymal Stem Cell Fate in
Human Tissue," FASEB
Journal, 25 (1), 122-131
(2011). [PDF]
2010
A.M. Kloxin, M.W.
Tibbitt, and K.S. Anseth,
“Synthesis of Photodegradable
Hydrogels as Dynamically Tunable
Cell Culture Platforms,"
Nature Protocols, 5 (12),
1867-1887 (2010). [PDF]
M.W. Tibbitt, A.M.
Kloxin, K.U. Dyamenahalli and
K.S. Anseth, “Controlled
Two-photon Photodegradation of
PEG Hydrogels to Study and
Manipulate Subcellular
Interactions on Soft Materials,"
Soft Matter, 6 (20),
5100-5108 (2010). [PDF]
A.M. Kloxin, C.J.
Kloxin, C.N. Bowman and K.S.
Anseth, “Mechanical
Properties of Cellularly
Responsive Hydrogels and
Their Experimental
Determination," Advanced
Materials, 22 (13),
3484-3494 (2010). [PDF]
B.D. Fairbanks, E.A.
Sims, K.S. Anseth and
C.N. Bowman, “Reaction Rates and
Mechanisms for Radical,
Photoinitiated Addition of
Thiols to Alkynes, and
Implications for Thiol-yne
Photopolymerizations and Click
Reactions," Macromolecules 43
(9), 4113-4119 (2010). [PDF]
C.A. DeForest, E.A.
Sims, and K.S. Anseth,
“Peptide-Functionalized Click
Hydrogels with Independently
Tunable Mechanics and Chemical
Functionality for 3D Cell
Culture," Chemistry of
Materials, 22, 4783-4790
(2010). [PDF]
L.M. Johnson, C.A.
DeForest, A. Pendurti, K.S.
Anseth and C.N. Bowman,
“Formation of Three-Dimensional
Hydrogel Multilayers Using
Enzyme-Mediated Redox Chain
Initiation," ASC Appl Mater
Interfaces, 2 (7),
1963-1972 (2010). [PDF]
M.C. Lawson, K.C. Hoth,
C.A. DeForest, C.N. Bowman, and
K.S. Anseth, “Inhibition
of Staphylococcus epidermidis
Biofilms using Polymerizable
Vancomycin Derivatives,"
Clin Orthop Relat Res,
468(8), 2081-2091 (2010).
[PDF]
A.A. Aimetti, K.R.
Feaver, and K.S. Anseth,
“Synthesis of Cyclic,
Multivalent Arg-Gly-Asp Using
Sequential Thiol-ene/Thiol-yne
Photoreactions," Chemical
Communications, 46 (31),
5781-3 (2010).
A.A. Aimetti, R.K.
Shoemaker, C.-C. Lin and K.S.
Anseth, “On- resin Peptide
Macrocyclization Using Thiol-ene
Click Chemistry," Chemical
Communications, 46 (23),
4061-4063 (2010). [PDF]
M.P. Schwartz, B.D.
Fairbanks, R.E. Rogers, R.
Rangarajan, M.H. Zaman and K.S.
Anseth, “A Synthetic
Strategy for Mimicking the
Extracellular Matrix Provides
New Insight About Tumor Cell
Migration," Integrative
Biology, 2, 32-40
(2010). [PDF]
P.S. Hume and K.S.
Anseth, “Induced Local T
Cell Apoptosis with
Anti-FAS-Functionalized
Polymeric Coatings Fabricated
Via Surface-Initiated
Photopolymerizations,"
Biomaterials, 31, 3166-3174
(2010). [PDF]
C.-C. Lin, P.D. Boyer,
A.A. Aimetti and K.S. Anseth,
“Regulated MCP-1 Diffusion in
Affinity Hydrogels for Enhancing
Immuno-isolation,"
Journal of Controlled Release,
142 (3), 384-391 (2010).
[PDF]
2009
J.A. Benton, C.A.
DeForest, V. Vivekanandan and K.S.
Anseth, “Photocrosslinking
of Geletin Macromers to
Synthesize Porous Hydrogels that
Promote Valvular Interstitial
Cell Function," Tissue
Engineering Part A, 15(11),
3221-3230 (2009). [PDF]
B.D. Fairbanks, M.P.
Schwartz, C.N. Bowman and K.S.
Anseth, “Photoinitiated
Polymerization of PEG-diacrylate
with Lithium
phenyl-2,4,6-trimethylbenzoylphosphinate:
Polymerization Rate and
Cytocompatibility,"
Biomaterials, 30,
6702-6707 (2009). [PDF]
M.C. Lawson, R.
Shoemaker, K.B. Hoth, C.N.
Bowman, and K.S. Anseth,
“Polymerizable Vancomycin
Derivatives for Bactericidal
Biomaterial Surface
Modification: Structure-Function
Evaluation,"
Biomacromolecules, 10,
2221-2234 (2009). [PDF]
B.D. Fairbanks, M.P.
Schwartz, A. E. Halevi, C.R.
Nuttleman, C.N. Bowman and K.S.
Anseth, “A Versatile
Synthetic Extracellular Matrix
Mimic via Thiol-Norbornene
Photoolymerization,"
Advanced Materials, 21(48),
5005-5010 (2009). [PDF]
J.A. Benton, B.D.
Fairbanks and K.S. Anseth,
“Characterization of Valvular
Interstitial Cell Function in
Three Dimensional Matrix
Metalloproteinase Degradable PEG
Hydrogels," Biomaterials,
30, 6593-6603 (2009). [PDF]
A.A. Aimetti, A.J.
Machen and K.S. Anseth,
“Poly(ethylene glycol) Hydrogels
Formed by Thiol-ene
Photopolymerization for
Enzyme-Responsive Protein
Delivery," Biomaterials, 30,
6048-6054 (2009). [PDF]
C.-C. Lin and K.S.
Anseth, “Glucagon-like
Peptide-1 Functionalized PEG
Hydrogels Promote Survival and
Function of Encapsulated
Pancreatic β-cells,"
Biomacromolecules, 10,
2460-2467(2009). [PDF]
A.M. Kloxin, J.A. Benton
and K.S. Anseth, “In
Situ Elasticity Modulation with
Dynamic Substrates to Direct
Cell Phenotype,"
Biomaterials, 31 (2009).
[PDF]
A.M. Kloxin, M.W.
Tibbitt, A.M. Kasko, J.F.
Fairbairn and K.S. Anseth,
“Tunable Hydrogels for External
Manipulation of Cellular
Microenvironments Through
Controlled Photodegradation,"
Advanced Materials,
21, (2009). [PDF]
M.W. Tibbitt, and K.S.
Anseth, “Hydrogels as
Extracellular Matrix Mimics for
3D Cell Culture,"
Biotechinology and
Bioengineering, 103,
655-663 (2009). [PDF]
C.A. DeForest, B.D.
Polizzotti and K.S. Anseth,
“Sequential Click Reactions for
Synthesizing and Patterning
Three-Dimensional Cell
Microenvironments," Nature
Materials, 8, 659-664
(2009). [PDF]
C.-C. Lin, A.T. Metters
and K.S. Anseth,
“Functional PEG-Peptide
Hydrogels to Modulate Local
Inflammation Induced by the
Pro-Inflammatory Cytokine TNFα," Biomaterials,
30, 4907-4914 (2009). [PDF]
C.-C. Lin and K.S.
Anseth, “Controlling
Affinity Binding in Peptide
Functionalized Poly(ethylene
glycol) Hydrogels,"
Advanced Functional Materials,
19, 2325-2331 (2009). [PDF]
A.A. Aimetti, M.W.
Tibbitt and K.S.
Anseth, “Human Neutrophil
Elastase Responsive Delivery
from Poly(ethylene glycol)
Hydrogels ,” Biomacromolecules,
10(6):1484-9 (2009). [PDF]
A.M. Kloxin, A.M.
Kasko, C.N. Salinas and K.S. Anseth,
“Photodegradable Hydrogels for
Dynamic Tuning of Physical and
Chemical Properties,” Science,
324, 59-63 (2009). [PDF]
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C.-C. Lin and K.S. Anseth,
“PEG Hydrogels for the
Controlled Release of
Biomolecules in Regenerative
Medicine,” Pharmaceutical
Research, 26, 631-43
(2009). [PDF]
B.D. Fairbanks, T.F.
Scott, C.J. Kloxin, K.S. Anseth
and C.N. Bowman “Thiol-Yne
Photopolymerization: Novel
Mechanism, Kinetics, and
Step-Growth Formation of Highly
Cross-Linked Networks,” Macromolecules,
42, 211-17 (2009). [PDF]
M.A. Rice, K.R. Waters
and K.S.
Anseth, “Ultrasound
Monitoring of Cartilaginous
Matrix Evolution in Degradable
PEG Hydrogels,” Acta
Biomaterialia, 5, 152-61
(2009). [PDF]
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2008
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L.M. Weber, K.N. Hayda
and K.S. Anseth,
“Cell-Matrix Interactions
Improve beta-Cell Survival and
Insulin Secretion in
Three-Dimensional Culture,” Tissue
Engineering Part A, 14,
1959-68 (2008). [PDF]
J.A. Benton, H.B. Kern
and K.S. Anseth,
“Substrate Properties Influence
Calcification in Valvular
Interstitial Cell Culture,”
Journal of Heart Valve Disease,
17, 689-99 (2008).
C.Y. Cheung, S.J.
McCartney and K.S. Anseth,
“Synthesis of Polymerizable
Superoxide Dismutase Mimetics to
Reduce Reactive Oxygen Species
Damage in Transplanted
Biomedical Devices,” Advanced
Functional Materials, 18,
3119-26 (2008). [PDF]
V.S. Khire, A.M. Kloxin,
C.L. Couch, K.S. Anseth
and C.N. Bowman, “Synthesis,
Characterization and Cleavage of
Linear Polymers Attached to
Silica Nanoparticles Formed
Using Thiol-Acrylate Conjugate
Addition Reactions,” Journal
of Polymer Science Part
A-Polymer Chemistry, 46,
6896-6906 (2008). [PDF]
M.A. Rice,
P.M. Homier, K.R. Waters and K.S.
Anseth, “Effects of
Directed Gel Degradation and
Collagenase Digestion on the
Integration of Neocartilage
Produced by Chondrocytes
Encapsulated in Hydrogel
Carriers,” Journal of Tissue
Engineering and Regenerative
Medicine, 2, 418-29
(2008). [PDF]
L.M. Weber and K.S.
Anseth, “Hydrogel
Encapsulation Environments
Functionalized with
Extracellular Matrix
Interactions Increase Islet
Insulin Secretion,” Matrix
Biology, 27, 667-73
(2008). [PDF]
D.S.W.
Benoit, M.P. Schwartz, A.R.
Durney and K.S. Anseth,
“Small Functional Groups for
Controlled Differentiation of
Hydrogel-Encapsulated Human
Mesenchymal Stem Cells,” Nature
Materials, 10, 816-23
(2008). [PDF]
C.N.
Salinas and K.S. Anseth,
“Mixed Mode Thiol-Acrylate
Photopolymerization for the
Synthesis of PEG-Peptide
Hydrogels,” Macromolecules,
41, 6019-26 (2008). [PDF]
A.M.
Kloxin and K.S. Anseth,
“Protein Gels on the Move,” Nature,
7205, 705-6(2008). [PDF]
C.N.
Salinas and K.S. Anseth,
“The Influence of the RGD
Peptide Motif and its Contextual
Presentation in PEG Gels on
Human Mesenchymal Stem Cell
Viability,” Journal of
Tissue Engineering and
Regenerative Medicine, 2,
296-304 (2008). [PDF]
A.E.
Rydholm, N.L. Held, D.S.W.
Benoit, C.N. Bowman and K.S.
Anseth, “Modifying Network
Chemistry in Thiol-Acrylate
Photopolymers Through
Postpolymerization
Functionalization to Control
Cell-Material Interactions,” Journal
of Biomedical Materials
Research Part A, 86A,
23-30 (2008). [PDF]
M.C.
Cushing, P.D. Mariner, J.T.
Liao, E.A. Sims and K.S.
Anseth, “Fibroblast Growth
Factor Represses Smad-Mediated
Myofibroblast Activation in
Aortic Valvular Interstitial
Cells,” FASEB Journal,
22, 1769-77 (2008). [PDF]
D.N. Shah, S.M.
Recktenwall-Work and K.S.
Anseth, “The Effect of
Bioactive Hydrogels on the
Secretion of Extracellular
Matrix Molecules by Valvular
Interstitial Cells,” Biomaterials,
29, 2060-72 (2008). [PDF]
H.M. Simms, C.N. Bowman
and K.S. Anseth, “Using
Living Radical Polymerization to
Enable Facile Incorporation of
Materials in Microfluidic Cell
Culture Devices,” Biomaterials,
29, 2228-36 (2008). [PDF]
C.N. Salinas and K.S.
Anseth, “The enhancement
of chondrogenic differentiation
of human mesenchymal stem cells
by enzymatically regulated RGD
functionalities,” Biomaterials,
29, 2370-77 (2008). [PDF]
B.D. Polizzotti, B.D.
Fairbanks and K.S. Anseth,
“Three-dimensional Biochemical
Patterning of Click-based
Composite Hydrogels via Thiolene
Photopolymerization,”
Biomacromolecules, 9,
1084-7 (2008). [PDF]
C.R. Nuttelman, M.A.
Rice, A.E. Rydholm, D.N. Shah
and K.S. Anseth,
“Macromolecular Monomers for the
Synthesis of Hydrogel Niches and
Their Application in Cell
Encapsulation and Tissue
Engineering,” Progress in
Polymer Science, 33,
167-79 (2008). [PDF]
L.M. Weber, C.Y. Cheung
and K.S. Anseth,
“Multifunctional pancreatic
islet encapsulation barriers
achieved via multilayer PEG
hydrogels,” Cell
Transplantation, 16,
1049-57 (2008).
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2007
D.S.W.
Benoit, S.D. Collins and K.S.
Anseth, “Multifunctional
Hydrogels that Promote
Osteogenic Human Mesenchymal
Stem Cell Differentiation
Through Stimulation and
Sequestering of Bone
Morphogenic Protein 2,” Advanced
Functional Materials,
17, 2085-93 (2007). [PDF]
M.C.
Lawson, C.N. Bowman and K.S.
Anseth, “Vancomycin
Derivative Photopolymerization
to Titanium Kills S.
epidermidis,” Clinical
Orthopaedics and Related
Research, 461, 96-105
(2007).
M.C.
Cushing, J-T. Liao, M.P. Jaeggli
and K.S. Anseth,
“Material-Based Regulation of
the Myofibroblast Phenotype,” Biomaterials,
28, 3378-87 (2007). [PDF]
K.K.
Macdonald, C.Y. Cheung and K.S.
Anseth, “Cellular
Delivery of TGF-beta1 Promotes
Osteoinductive Signalling for
Bone Regeneration,” Journal
of Engineering and
Regenerative Medicine,
1, 314-17 (2007). [PDF]
A.E.
Rydholm, S.K. Reddy, K.S.
Anseth and C.N. Bowman
“Development and
Characterization of Degradable
Thiol-Allyl Ether
Photopolymers,” Polymer,
48, 4589-4600 (2007). [PDF]
A.W.
Watkins, S.L. Southard and K.S.
Anseth, “Characterizing
Multilaminated Hydrogels with
Spatially Varying Network
Structure and Solute Loading
Using Confocal Laser Scanning
Microscopy,” Acta
Biomaterialia, 3,
439-448 (2007). [PDF]
A.E.
Rydholm, K.S. Anseth
and C.N. Bowman “Effects of
Neighboring Sulfides and pH on
Ester Hydrolysis in
Thiol-Acrylate Photopolymers,”
Acta Biomaterialia, 3,
449-455 (2007). [PDF]
L.M.
Weber, K.N. Hayda, K. Haskins
and K.S. Anseth, “The
Effects of Cell-Matrix
Interactions on Encapsulated
Beta-Cell Function within
Hydrogels Functionalized with
Matrix-Derived Adhesive
Peptides,” Biomaterials,
28, 3004-11 (2007). [PDF]
C.N. Salinas, B.B. Cole,
A.M. Kasko and K.S. Anseth,
“Chondrogenic Differentiation
Potential of Human Mesenchymal
Stem Cells Photoencapsulated
within Poly(ethylene
glycol)-Arginine-Glycine-Aspartic
Acid-Serine Thiol-Methacrylate
Mixed-Mode Networks,” Tissue
Engineering, 13, 1025-34
(2007). [PDF]
M.C.
Cushing and K.S. Anseth,
“Hydrogel Cell Cultures,” Science,
316, 1133-34 (2007). [PDF]
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D.S.W. Benoit,
M.C. Tripodi, J.O. Blanchette, S.J.
Langer, L.A. Leinwand and K.S.
Anseth, “Integrin-Linked Kinase
Production Prevents Anoikis in Human
Mesenchymal Stem Cells,” Journal of
Biomedical Materials Research Part A,
81A, 269-278 (2007). [PDF]
M.J. Mahoney and K.S.
Anseth, “Contrasting Effects of
Collagen and bFGF-2 on Neural Cell
Function in Degradable Synthetic PEG
Hydrogels,” Journal of Biomedical
Materials Research Part A, 81A,
1133-34 (2007). [PDF]
E.M.
Christenson, K.S. Anseth, J.J.P.
van den Beucken, C.K. Chan, B. Ercan,
J.A. Jansen, C.T. Laurencin, W.J. Li, R.
Murugan, L.S. Nair, S.
Ramakrishna, R.S. Tuan, T.J. Webster and
A.G. Mikos, “Nanobiomaterial
Applications in Orthopaedics,” Journal
of Orthopaedic Research, 25,
11-22 (2007). [PDF]
J.A. Cooper, W.J.
Li, L.O. Bailey, S.D. Hudson, S.
Lin-Gibson, K.S. Anseth, R.S.
Tuan and N.R. Washburn, “Encapsulated
Chondrocyte Response in a Pulsatile Flow
Bioreactor,” Acta Biomaterialia,
3, 13-21 (2007). [PDF]
D.S.W. Benoit, A.R. Durney and
K.S. Anseth, “The Effects of
Heparin-functionalized PEG Hydrogels on
Three-dimensional Human Mesenchymal Stem
Cell Osteogenic Differentiation,” Biomaterials,
28, 66-77 (2007). [PDF]
R.P. Sebra, S.K. Reddy, K.S.
Masters, C.N. Bowman and K.S. Anseth,
“Controlled Polymerization Chemistry to
Graft Architectures that Influence
Cell-Material Interactions,” Acta
Biomaterialia, 3, 151-161
(2007). [PDF]
M.A. Rice and K.S. Anseth,
“Controlling Cartilaginous Matrix
Evolution in Hydrogels with Degradation
Triggered by Exogenous Addition of an
Enzyme,” Tissue Engineering, 13,
683-691 (2007). [PDF]
K.W. Riddle, H.J.
Kong, K.J. Leach, C. Fischbach, C.Y.
Cheung, K.S. Anseth and D.J.
Mooney, “Modifying the Proliferative
State of Target Cells to Control DNA
Expression and Identifying Cell Types
Transfected In Vivo,” Molecular
Therapy, 15, 361-8 (2007). [PDF]
M.J.
Mahoney and K.S. Anseth,
“Contrasting Effects of Collagen and
bFGF-2 on Neural Cell Function in
Degradable Synthetic PEG Hydrogels,”
Journal of Biomedical Materials
Research, 81A, 269-78(2006).
[PDF]
A.E. Rydholm, S.K. Reddy, K.S.
Anseth and C.N. Bowman,
“Controlling Network Structure in
Degradable Thiol-Acrylate Biomaterials
to Tune Mass Loss Behavior,”
Biomacromolecules, 7,
2827-36 (2006). [PDF]
V.S. Khire, D.S.W. Benoit, K.S.
Anseth and C.N. Bowman, “Ultrathin
gradient films using thiol-ene
polymerizations,” Journal of Polymer
Science, Polymer Chemistry, 44,
7027-39 (2006). [PDF]
D.S.W. Benoit, C.R. Nuttelman,
S.D. Collins and K.S. Anseth,,
“Synthesis and Characterization of
a Fluvastatin-Releasing Hydrogel
Delivery System to Modulate hMSC
Differentiation and Functions for Bone
Regeneration,” Biomaterials, 27,
6102-10 (2006). [PDF]
M.A.
Rice, J. Sanchez-Adams and K.S.
Anseth,
“Exogenously Triggered, Enzymatic
Degradation of Photopolymerized
Hydrogels with Polycaprolactone
Subunits:
Experimental Observation and Modelling of
Mass Loss Behavior,” Biomacromolecules,
7(6): 1968-1975, (2006). [PDF]
C.Y. Cheung and
K.S.
Anseth,
“Synthesis of immunoisolation
barriers that provide localized immunosuppression
for encapsulated pancreatic islets,” Bioconjugate
Chemistry, 17,
1036-42 (2006). [PDF]
V.S. Khire, A.W. Harant, A.W.
Watkins, K.S.
Anseth,
and C.N. Bowman, “Ultrathin
Patterned Polymer Films on Surfaces
using Thiol-ene
Polymerizations,” Macromolecules,
39,
5081-86 (2006). [PDF]
R.P. Sebra, K.S. Anseth and
C.N. Bowman, “Integrated surface
modification of fully polymeric
microfluidic devices using living
radical photopolymerization
chemistry,” Journal
of Polymer Science, Polymer
Chemistry, 44, 1404-13 (2006).
[PDF]
L.M. Weber, J.
He, B. Bradley, K. Haskins and K.S.
Anseth,
"PEG-based hydrogels as an in
vitro encapsulation platform for
testing controlled beta cell
microenvironments," Acta
Biomaterialia,
2, 1-8 (2006). [PDF]
C.R.
Nuttelman, A.M. Kloxin
and K.S.
Anseth,
"Temporal Changes in PEG Hydrogel Structure
Influence Human Mesenchymal Stem Cell
Proliferation and Matrix
Mineralization," Advances
in Experimental Medicine and
Biology,
in press (2006). [PDF]
C.R.
Nuttelman, M.C. Tripodi
and K.S.
Anseth,
“Dexamethasone-Functionalized Gels
Induce Osteogenic Differentiation of
Encapsulated hMSCs,” Journal
of Biomedical Materials Research,
76A, 183-95 (2006). [PDF]
K.T. Haraldsson,
J.B. Hutchison, R.P. Sebra, B.T.
Good, K.S.
Anseth
and C.N. Bowman, “3D polymeric microfluidic
device fabrication via contact liquid
photolithographic polymerization (CLiPP),” Sensors
and Actuators B, 113,
454-60 (2006). [PDF]
D.S.W. Benoit,
A.R. Durney
and K.S.
Anseth,
"Manipulations in hydrogel degradation
behavior enhance osteoblast
function and mineralized tissue
formation," Tissue
Engineering, 12, 1663-1673
(2006). [PDF]
M.J. Mahoney
and K.S.
Anseth,
“ Three-Dimensional
Growth and Function of Neural Tissue
in Degradable Polyethylene Glycol
Hydrogels,”
Biomaterials, 27, 2665-74
(2006). [PDF]
C.R. Nuttelman,
D.S.W. Benoit, M.C. Tripodi and K.S.
Anseth,
“The Effects of Ethylene Glycol
Methacrylate Phosphate in PEG
Hydrogels on Mineralization and
Viability of Encapsulated hMSCs,” Biomaterials,
27,
1377-1386 (2006). [PDF]
R.P. Sebra, K.S.
Masters, C.Y. Cheung, C.N. Bowman and
K.S. Anseth,
“Detection of Antigens in
Biologically Complex Fluid with Photografted
Whole Antibodies,” Analytical
Chemistry, 78,
3144-51 (2006).
[PDF]
J.B. Hutchison, P.F.
Stark, C.J. Hawker, and K.S. Anseth, “Polymerizable
Living Free Radical Initiators as a
Platform to Synthesize Functional
Networks,” Chemistry
of Materials, 17, 4789-97 (2005).
[PDF]
D.S.W. Benoit and K.S. Anseth,
“Heparin Functionalized PEG Hydrogels
that Modulate Protein Adsorption for
hMSC Adhesion and Differentiation,” Acta Biomaterialia,
1, 461-470 (2005). [PDF]
S.K. Reddy, K.S. Anseth,
and C.N. Bowman, “Modeling of Network
Degradation in Mixed Step-Chain Growth
Polymerizations,”
Polymer, 46, 4212-22 (2005). [PDF]
C.R. Nuttelman, M.C. Tripodi, and K.S.
Anseth,
“Synthetic Hydrogel Niches that Promote
hMSC Viability,” Matrix
Biology, 24,
208-18 (2005). [PDF]
M.C. Cushing, K.S.
Masters, L.A.
Leinwand,
and K.S. Anseth,
“Serum Deprivation Improves Seeding and
Repopulation of Acellular
Matrices with Valvular
Interstitial Cells,” Journal
of Biomedical Materials Research, 75A,
232-41 (2005). [PDF]
S.K. Reddy, R.P. Sebra, K.S.
Anseth,
and C.N. Bowman, “Living Radical Photopolymerization
Induced Grafting on Thiol-Ene Based
Substrates,” Journal
of Polymer Science, Part A: Polymer
Chemistry, 43, 2134-44 (2005). [PDF]
D.S.W. Benoit and K.S.
Anseth,
“The Effect on Osteoblast Function of
Colocalized RGD and PHSRN Epitopes on PEG
Surfaces,” Biomaterials, 26,
5209-20 (2005).
H.S. Simms, C.M.
Brotherton, B.T. Good, R.H. Davis, K.S.
Anseth,
and C.N. Bowman, “In Situ
Fabrication of
Macroporous Polymer Networks
within Microfluidic Devices by Living
Radical Photopolymerization
and Leaching,” Lab on a Chip, 5,
151-57 (2005). [PDF]
A.E. Rydholm, C.N.
Bowman, and K.S. Anseth,
“Degradable
Thiol-Acrylate Photopolymers:
Polymerization and Degradation Behavior
of an In Situ Forming
Biomaterial,” Biomaterials, 26,
4495-506 (2005). [PDF]
S.J. Bryant, J.A. Arthur,
and K.S. Anseth,
“Incorporation of Tissue-Specific
Molecules Alters Chondrocyte Metabolism
and Gene Expression in Photocrosslinked
Hydrogels,” Acta
Biomaterialia,
1, 243-52 (2005). [PDF]
A.W. Watkins and K.S.
Anseth,
“Investigation of Molecular Transport
and Distributions in Poly(ethylene
glycol) Hydrogels with Confocal Laser
Scanning Microscopy,” Macromolecules,
38, 1326-34 (2005). [PDF]
T.M. Lovestead, J.A.
Burdick, K.S. Anseth,
and C.N. Bowman, “Understanding Multivinyl
Monomer
Photopolymerization Kinetics
through Modeling and GPC Investigation
of Degradable Networks,” Polymer,
16,
6226-34 (2005). [PDF]
K.S. Masters, D.N. Shah,
L.A.
Leinwand,
and K.S. Anseth,
“Crosslinked
Hyaluronan
Scaffolds as a Biologically Active
Carrier for Valvular
Interstitial Cells,” Biomaterials,
26, 2517-25 (2005). [PDF]
J. B. Hutchison, A. Lindquist
and K.S. Anseth, “Off-Lattice
Simulation of Multifunctional Monomer
Polymerizations: Effects of Monomer
Mobility, Structure, and Functionality
on Structural Evolution at Low
Conversion,” Journal of Physical
Chemistry B, 108, 11097-11104
(2004). [PDF]
D.J. Quick, K.K. Macdonald and
K.S. Anseth, “Delivering DNA from
Photocrosslinked, Surface-eroding
Polyanhydrides,” Journal of
Controlled Release, 97, 333-43
(2004). [PDF]
J.B. Hutchison, K.T.
Haraldsson, B.T. Good, R.P. Sebra, N.
Luo, K.S. Anseth and C.N.
Bowman, “Robust Polymer Microfluidic
Device Fabrication Via Contact Liquid
Photolithographic Polymerization
(CLiPP),” Lab on a Chip, 4,
658-62 (2004). [PDF]
J.B. Hutchison, A.S. Lindquist
and K.S. Anseth, “Experimental
Characterization of Structural Features
during Radical Chain Homopolymerization
of Multifunctional Monomers Prior to
Macroscopic Gelation: Application to
Methacrylic Anhydride,” Macromolecules,
37, 3823-31 (2004). [PDF]
S.J. Bryant, K.A.
Davis-Arehart, N. Luo, R.K. Shoemaker,
J.A. Arthur and K.S. Anseth,
“Synthesis and Characterization of
Photopolymerized Multifunctional
Hydrogels: Water-soluble Poly(vinyl
alcohol) and Chondroitin Sulfate
Macromers for Chondrocyte
Encapsulation,” Macromolecules,
37, 6726-33 (2004). [PDF]
K.S. Masters, D.N. Shah, G.
Walker, L.A. Leinwand and K.S.
Anseth, “Designing Scaffolds for
Valvular Interstitial Cells: Cell
Adhesion and Function on
Naturally-Derived Materials,” Journal
of Biomedical Materials Research, 71A,
172-80 (2004). [PDF]
M.A. Rice and K.S. Anseth,
“Encapsulating Chondrocytes in
Copolymer Gels: Bimodal Degradation
Kinetics Influence Cell Phenotype and
Extracellular Matrix Development,” Journal
of Biomedical Materials Research,
70A, 560-68 (2004). [PDF]
S.J. Bryant, T.T. Chowdhury, K.S.
Anseth, D.A. Lee and D.L. Bader,
“Crosslinking Density Influences the
Morphology of Chondrocytes
Photoencapsulated in PEG Hydrogels
During the Application of Compressive
Strain,” Journal of Orthopaedic
Research, 22, 1143-49 (2004). [PDF]
S.J. Bryant, R.J. Bender, K.L.
Durand and K.S. Anseth,
“Encapsulating Chondrocytes in Degrading
PEG Hydrogels with High Modulus:
Engineering Gel Structural Changes to
Facilitate Cartilaginous Tissue
Production,” Biotechnology and
Bioengineering, 86, 747-55 (2004). [PDF]
G.A. Walker, K.S. Masters, D.N.
Shah, K.S. Anseth and L.A.
Leinwand, “Valvular Myofibroblast
Activation by TGF-beta: Implications for
Pathological ECM Remodeling in Heart
Valve Disease,” Circulation Research,
95, 253-60 (2004). [PDF]
P.J. Martens, C.N. Bowman and K.S.
Anseth, “Degradable Networks
Formed from Multifunctional Poly(Vinyl
Alcohol) Macromers: Comparison of
Results from a Generalized
Bulk-Degradation Model for Polymer
Networks and Experimental Data,” Polymer,
45, 3377-3387 (2004). [PDF]
D.J. Quick and K.S. Anseth,
“DNA Delivery from Photocrosslinked PEG
Hydrogels: Encapsulation Efficiency,
Release Profiles, and DNA Quality,” Journal
of Controlled Release, 96(2),
341-51 (2004). [PDF]
C.R. Nuttelman, M.C. Tripodi
and K.S. Anseth, “In Vitro
Osteogenic Differentiation of Human
Mesenchymal Stem Cells Photoencapsulated
in PEG Hydrogels,” Journal of
Biomedical Materials Research, 68A(4),
773-82 (2004). [PDF]
S.J. Bryant, T.T. Chowdhury,
D.A. Lee, D.L. Bader and K.S.
Anseth, “Crosslinking Density
Influences Chondrocyte Metabolism in
Dynamically Loaded Photocrosslinked PEG
Hydrogels,” Annals of Biomedical
Engineering, 32, 407-17,
(2004). [PDF]
M.A. Randolph, K.S. Anseth
and M.J. Yaremchuk, “Tissue Engineering
of Cartilage,” Clinics in Plastic
Surgery, 30, 519-37 (2003).
D.J. Quick and K.S. Anseth,
“Gene Delivery in Tissue Engineering: A
Photopolymer Platform to Co-encapsulate
Cells and Plasmid DNA,” Pharmaceutical
Research, 20, 1730-37 (2003). [PDF]
N. Luo, A.T. Metters, J.B.
Hutchison, C.N. Bowman, and K.S.
Anseth, “A Methacrylated
Photoinferter as a Chemical Basis for
Microlithography: Micropatterning Based
on Photo-Grafting Polymerization,” Macromolecules,
36, 6739-45 (2003). [PDF]
S.J. Bryant, K.L. Durand and K.S.
Anseth, “Manipulations in
Hydrogel Chemistry Control
Photoencapsulated Chondrocyte Behavior
and their Extracellular Matrix
Production,” Journal of Biomedical
Materials Research, 67, 1430-36
(2003). [PDF]
J. Owens, K.S. Anseth
and T.W. Randolph, “Mechanism of
Microparticle Formation in the
Compressed Antisolvent Precipitation and
Photopolymerization Process,”
Langmuir, 19, 3926-34 (2003). [PDF]
A.W. Watkins and K.S.
Anseth, “Copolymerization of
Photocrosslinkable Anhydride Monomers
for Use as a Biodegradable Bone Cement,”
Journal of Biomaterials Science,
Polymer Edition, 14, 267-78
(2003).
J.A. Burdick, T.M. Lovestead
and K.S. Anseth, “Kinetic Chain
Lengths in Highly Crosslinked Networks
Formed by the Photoinitiated
Polymerization of Degradable Divinyl
Monomers: A GPC Investigation,” Biomacromolecules,
4, 149-56 (2003). [PDF]
K.A. Davis, J.A. Burdick and K.S.
Anseth, “Photoinitiated
Crosslinked Degradable Copolymer
Networks for Tissue Engineering
Applications,” Biomaterials, 24, 2485-95
(2003). [PDF]
A.K. Poshusta, J.A. Burdick,
D.J. Mortisen, R.F. Padera, D. Ruehlman,
M.J. Yaszemski and K.S. Anseth,
“Histocompatibility of Photocrosslinked
Polyanhydrides: A Novel In
Situ Forming Orthopaedic
Biomaterial,” Journal of Biomedical
Materials Research, 64A, 62-69
(2003). [PDF]
P.J. Martens, S.J. Bryant and K.S.
Anseth, “Tailoring the Degradation
of Hydrogels Formed from Multivinyl
Poly(ethylene glycol) and Poly(vinyl
alcohol) Macromers for Cartilage Tissue
Engineering,” Biomacromolecules, 4,
283-92 (2003). [PDF]
S.J. Bryant and K.S. Anseth,
“Controlling the Spatial Distribution of
ECM Components in Degradable PEG
Hydrogels for Tissue Engineering
Cartilage,” Journal of Biomedical
Materials Research, 64A, 70-79
(2003). [PDF]
K.A. Davis and K.S. Anseth,
“Controlled Release from Crosslinked
Degradable Networks,” Critical
Reviews in Therapeutic Drug Carrier
Systems, 19, 385-423 (2002).
J.A. Burdick, R.F. Padera, J.V.
Huang and K.S. Anseth, “An
Investigation of the Cytotoxicity and
Histocompatibility of In Situ
Forming Lactic Acid Based Orthopaedic
Biomaterials,” Journal of Biomedical
Materials Research, Applied
Biomaterials, 63, 484-91 (2002). [PDF]
J.A. Burdick, D. Frankel, W.S.
Dernell and K.S. Anseth, “An
Initial Investigation of Photocurable
3-Dimensional Lactic Acid Based
Scaffolds in a Critical-Sized Cranial
Defect,” Biomaterials, 24, 1613-20
(2003). [PDF]
J.A. Burdick, M.N. Mason, A.D.
Hinman, K. Thorne and K.S. Anseth,
“Delivery of Osteoinductive Growth
Factors from Degradable PEG Hydrogels
Influences Osteoblast Differentiation
and Mineralization,” Journal of
Controlled Release, 83, 53-63
(2002). [PDF]
P. Martens, T. Holland and K.S.
Anseth, “Synthesis and
Characterization of Degradable Hydrogels
Formed from Acrylate Modified Poly(Vinyl
Alcohol) Macromers,” Polymer, 43, 6093-6100
(2002). [PDF]
A.K. Poshusta, C.N. Bowman and
K.S. Anseth, “Application of a
Kinetic Gelation Simulation to the
Characterization of In Situ
Crosslinking Biomaterials,” Journal
of Biomaterials Science, Polymer
Edition, 13, 797-815
(2002).
J.A. Burdick and K.S.
Anseth, “Photoencapsulation of
Osteoblasts in Injectable RGD-Modified
PEG Hydrogels for Bone Tissue
Engineering Applications,” Biomaterials,
23, 4315-23 (2002).
[PDF]
S.J. Bryant and K.S.
Anseth, “Hydrogel Properties
Influence ECM Production by Chondrocytes
Photoencapsulated in Poly(ethylene
glycol) Hydrogels,” Journal of
Biomedical Materials Research, 59,
63-72 (2002). [PDF]
K.S. Anseth and J.A.
Burdick, “New Directions in
Photopolymerizable Biomaterials,”
MRS Bulletin, 1-7, (Feb., 2002).
C.R. Nuttelman, S.M. Henry and
K.S. Anseth, “Synthesis and
Characterization of Photocrosslinkable,
Degradable Poly(vinyl alcohol)-based
Tissue Engineering Scaffolds,” Biomaterials,
23, 3617-26 (2002). [PDF]
J.L Owens, K.S. Anseth
and T.W. Randolph, “Compressed Antisolvent
Precipitation and Polymerization to
Form Highly Crosslinked Polymer
Particles,” Macromolecules,
35, 4289-96 (2002).
[PDF]
N. Luo, J.B. Hutchison, K.S.
Anseth and C.N. Bowman, “Synthesis
of A Novel Methacrylic Monomer-Iniferter
and Its Application in Surface
Photo-Grafting on Crosslinked Polymer
Substrates,” Journal of
Polymer Science Part A: Polymer
Chemistry, 40, 1885-91 (2002). [PDF]
N. Luo, J.B. Hutchison, K.S.
Anseth and C.N. Bowman,
“Surface-Initiated Photopolymerization
of Poly(ethylene glycol) Methyl Ether
Methacrylate on a
Diethyldithiocarbamate-Mediated Polymer
Substrate,” Macromolecules, 35,
2487-93 (2002). [PDF]
K.S. Anseth, A.T. Metters, S.J. Bryant,
P.J. Martens, J.H. Elisseeff and C.N.
Bowman, “In Situ Forming
Degradable Networks and Their
Application in Tissue Engineering and
Drug Delivery,” Journal of
Controlled Release, 78,
199-209 (2002). [PDF]
L. Liew, W. Zhang, L. An, S.
Shah, R. Luo, Y. Liu, T. Cross, M.L.
Dunn, V. Bright, J.W. Daily, R. Raj and
K.S. Anseth, “Ceramic MEMS: New
Materials, Innovative Processing and
Future Applications,” American
Ceramic Society Bulletin, 80,
25-30 (2001). [PDF]
J.A. Burdick, M.N. Mason and K.S.
Anseth, “In Situ Forming
Lactic Acid Based Orthopaedic
Biomaterials: Influence of Oligomer
Chemistry on Osteoblast Attachment and
Function,” Journal of Biomaterials
Science, Polymer Edition, 12,
1253-65 (2001).
C.R. Nuttelman, D.J. Mortisen,
S.M. Henry and K.S. Anseth,
“Attachment of Fibronectin to Poly(Vinyl
Alcohol) Hydrogels Promotes NIH3T3 Cell
Adhesion, Proliferation, and Migration,”
Journal of Biomedical Materials
Research, 57, 217-223 (2001). [PDF]
J.B. Hutchison and K.S.
Anseth, “An Off-Lattice Approach
to Simulate Radical Chain Polymerization
of Tetrafunctional Monomers,” Macromolecular
Theory and Simulations, 10, 600-607
(2001). [PDF]
M. N. Mason, A.T. Metters, C.N.
Bowman and K.S. Anseth,
“Predicting Controlled-Release Behavior
of Degradable PLA-b-PEG-b-PLA
Hydrogels,” Macromolecules, 34,
4630-35 (2001). [PDF]
J.A. Burdick, L.M. Philpott and
K.S. Anseth, “Synthesis and
Characterization of Tetrafunctional
Lactic Acid Oligomers: A Potential In
Situ Forming Orthopaedic
Biomaterial,” Journal of Polymer
Science, A, Polymer Chemistry, 39,
683-92 (2001). [PDF]
P. Martens, A.T. Metters, K.S.
Anseth and C.N. Bowman, “A
Generalized Bulk-Degradation Model for
Hydrogel Networks Formed from Multi
Vinyl Cross-linking Molecules,” Journal
of Physical Chemistry B, 105,
5131-38 (2001). [PDF]
A.T. Metters, C.N. Bowman and K.S.
Anseth, “A Statistical Kinetic
Model for the Bulk Degradation of
PLA-b-PEG-b-PLA Hydrogel Networks:
Incorporating Network Non-Idealities,” Journal
of Physical Chemistry B, 105, 8069-8076
(2001). [PDF]
J.A. Burdick, A.J. Peterson and
K.S. Anseth, “Conversion and
Temperature Profiles During the
Photoinitiated Polymerization of Thick
Orthopaedic Biomaterials,”
Biomaterials, 22, 1779-86 (2001). [PDF]
A.K. Poshusta and K.S.
Anseth, “Photopolymerized
Biomaterials for Applications in the
Temporomandibular Joint,” Cells
Tissues Organs, 169,
272-78 (2001).
D.J. Quick and K.S. Anseth,
“Polymerizations of Multifunctional
Anhydride Monomers to Form Highly
Crosslinked Degradable Networks,” Macromolecular
Rapid Communications, 22, 564-72
(2001). [PDF]
A.T. Metters, C.N. Bowman and K.S.
Anseth, “Verification of Scaling
Laws for Degrading PLA-b-PEG-b-PLA
Hydrogels,” AIChE Journal, 47,
1432-37 (2001). [PDF]
S.J. Bryant and K.S. Anseth,
“The Effect of Scaffold Thickness on
Tissue Engineered Cartilage in
Photocrosslinked Poly(ethylene oxide)
Hydrogels,” Biomaterials, 22, 619-26 (2001). [PDF]
A.T. Metters, K.S. Anseth
and C.N. Bowman, “A Statistical Kinetic
Model for the Bulk-Degradation of
PEG-b-PLA Hydrogel Networks,” Journal
of Physical Chemistry B, 104,
7043-49 (2000). [PDF]
P. Martens and K.S. Anseth,
“Characterization of Hydrogels Formed
from Acrylate Modified Poly (Vinyl
Alcohol) Macromers,” Polymer, 41,
7715-22 (2000). [PDF]
A.K. Burkoth, J.A. Burdick and
K.S. Anseth, “Surface and Bulk
Modifications to Photocrosslinked
Polyanhydrides to Control Degradation
Behavior,” Journal of Biomedical
Materials Research, 51,
352-59 (2000). [PDF]
A.K. Burkoth and K.S.
Anseth, “A Review of
Photocrosslinked Polyanhydrides: In
Situ Forming Degradable
Networks,” Biomaterials, 21,
2395-2404 (2000). [PDF]
J. Elisseeff, W. McIntosh, K.
Anseth, S. Riley, P. Ragan and R.
Langer, “Photoencapsulation of
Chondrocytes in Poly(Ethylene
Oxide)-Based Semi-Interpenetrating
Networks,” Journal of Biomedical
Materials Research, 51, 164-171
(2000). [PDF]
S. Lu and K.S. Anseth,
“Release Behavior of High Molecular
Weight Solutes From Poly(ethylene
glycol)-Based Degradable Networks,” Macromolecules,
33, 2509-2515 (2000). [PDF]
A.T. Metters, K.S. Anseth
and C.N. Bowman, “Fundamental Studies of
a Novel, Biodegradable PEG-b-PLA
Hydrogel,” Polymer, 41,
3993-4004 (2000). [PDF]
S. Lu, W.F. Ramirez and K.S.
Anseth, “Photopolymerized,
Multilaminated Matrix Devices with
Optimized Nonuniform Initial
Concentration Profiles to Control Drug
Release,” Journal of Pharmaceutical
Sciences, 89, 45-51 (2000). [PDF]
J.S. Young, K.D. Gonzales and K.S.
Anseth, “Photopolymers in
Orthopedics: Characterization of
Novel Crosslinked Polyanhydrides,” Biomaterials,
21, 1181-88 (2000). [PDF]
S.J. Bryant, C.R. Nuttelman and
K.S. Anseth, “Cytocompatibility
of UV and visible light photoinitiating
systems on cultured NIH/3T3
fibroblasts,” Journal of
Biomaterials Science. Polymer
Edition/i>, 11, 439-57 (2000).
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