Recent Publications

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2009

B.D. Fairbanks, M.P. Schwartz, C.N. Bowman and K.S. Anseth, “Photoinitiated Polymerization of PEG-diacrylate with Lithium phenyl-2,4,6-trimethylbenzoylphosphinate: Polymerization Rate and Cytocompatibility," Biomaterials, 30, 6702-6707 (2009). [PDF]

M.C. Lawson, R. Shoemaker, K.B. Hoth, C.N. Bowman, and K.S. Anseth, “Polymerizable Vancomycin Derivatives for Bactericidal Biomaterial Surface Modification: Structure-Function Evaluation," Biomacromolecules, 10, 2221-2234 (2009). [PDF]

J.A. Benton, B.D. Fairbanks and K.S. Anseth, “Characterization of Valvular Interstitial Cell Function in Three Dimensional Matrix Metalloproteinase Degradable PEG Hydrogels," Biomaterials, 30, 6593-6603 (2009). [PDF]

A.A. Aimetti, A.J. Machen and K.S. Anseth, “Poly(ethylene glycol) Hydrogels Formed by Thiol-ene Photopolymerization for Enzyme-Responsive Protein Delivery," Biomaterials, 30, 6048-6054 (2009). [PDF]

C.-C. Lin and K.S. Anseth, “Glucagon-like Peptide-1 Functionalized PEG Hydrogels Promote Survival and Function of Encapsulated Pancreatic β-cells," Biomacromolecules, In Press (2009). [PDF]

A.M. Kloxin, J.A. Benton and K.S. Anseth, “In Situ Elasticity Modulation with Dynamic Substrates to Direct Cell Phenotype," Biomaterials, 31 (2009). [PDF]

A.M. Kloxin, M.W. Tibbitt, A.M. Kasko, J.F. Fairbairn and K.S. Anseth, “Tunable Hydrogels for External Manipulation of Cellular Microenvironments Through Controlled Photodegradation," Advanced Materials, 21,  (2009). [PDF]

M.W. Tibbitt, and K.S. Anseth, “Hydrogels as Extracellular Matrix Mimics for 3D Cell Culture," Biotechinology and Bioengineering, 103, 655-663 (2009). [PDF]

C.A. DeForest, B.D. Polizzotti and K.S. Anseth, “Sequential Click Reactions for Synthesizing and Patterning Three-Dimensional Cell Microenvironments," Nature Materials, 8, 659-664 (2009). [PDF]

C.-C. Lin, A.T. Metters and K.S. Anseth, “Functional PEG-Peptide Hydrogels to Modulate Local Inflammation Induced by the Pro-Inflammatory Cytokine TNFα," Biomaterials, 30, 4907-4914 (2009). [PDF]

C.-C. Lin and K.S. Anseth, “Controlling Affinity Binding in Peptide Functionalized Poly(ethylene glycol) Hydrogels," Advanced Functional Materials, 19, 2325-2331 (2009). [PDF]

A.A. Aimetti, M.W. Tibbitt and K.S. Anseth, “Human Neutrophil Elastase Responsive Delivery from Poly(ethylene glycol) Hydrogels ,” Biomacromolecules, 10(6):1484-9 (2009). [PDF]

A.M. Kloxin, A.M.  Kasko, C.N. Salinas and K.S. Anseth, “Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties,” Science, 324, 59-63 (2009). [PDF]

C.-C. Lin and K.S. Anseth, “PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine,” Pharmaceutical Research, 26, 631-43 (2009). [PDF]

B.D. Fairbanks, T.F. Scott, C.J. Kloxin, K.S. Anseth and C.N. Bowman “Thiol-Yne Photopolymerization: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks,” Macromolecules, 42, 211-17 (2009). [PDF]

M.A. Rice, K.R. Waters and K.S. Anseth, “Ultrasound Monitoring of Cartilaginous Matrix Evolution in Degradable PEG Hydrogels,” Acta Biomaterialia, 5, 152-61 (2009). [PDF]

2008

L.M. Weber, K.N. Hayda and K.S. Anseth, “Cell-Matrix Interactions Improve beta-Cell Survival and Insulin Secretion in Three-Dimensional Culture,” Tissue Engineering Part A, 14, 1959-68 (2008).  [PDF]

J.A. Benton, H.B. Kern and K.S. Anseth, “Substrate Properties Influence Calcification in Valvular Interstitial Cell Culture,” Journal of Heart Valve Disease, 17, 689-99 (2008). 

C.Y. Cheung, S.J. McCartney and K.S. Anseth, “Synthesis of Polymerizable Superoxide Dismutase Mimetics to Reduce Reactive Oxygen Species Damage in Transplanted Biomedical Devices,” Advanced Functional Materials, 18, 3119-26 (2008).  [PDF]

V.S. Khire, A.M. Kloxin, C.L. Couch, K.S. Anseth and C.N. Bowman, “Synthesis, Characterization and Cleavage of Linear Polymers Attached to Silica Nanoparticles Formed Using Thiol-Acrylate Conjugate Addition Reactions,” Journal of Polymer Science Part A-Polymer Chemistry, 46, 6896-6906 (2008).  [PDF]

M.A. Rice, P.M. Homier, K.R. Waters and K.S. Anseth, “Effects of Directed Gel Degradation and Collagenase Digestion on the Integration of Neocartilage Produced by Chondrocytes Encapsulated in Hydrogel Carriers,” Journal of Tissue Engineering and Regenerative Medicine, 2, 418-29 (2008). [PDF]

L.M. Weber and K.S. Anseth, “Hydrogel Encapsulation Environments Functionalized with Extracellular Matrix Interactions Increase Islet Insulin Secretion,” Matrix Biology, 27, 667-73 (2008). [PDF]

D.S.W. Benoit, M.P. Schwartz, A.R. Durney and K.S. Anseth, “Small Functional Groups for Controlled Differentiation of Hydrogel-Encapsulated Human Mesenchymal Stem Cells,” Nature Materials, 10, 816-23 (2008). [PDF]

C.N. Salinas and K.S. Anseth, “Mixed Mode Thiol-Acrylate Photopolymerization for the Synthesis of PEG-Peptide Hydrogels,” Macromolecules, 41, 6019-26 (2008). [PDF]

A.M. Kloxin and K.S. Anseth, “Protein Gels on the Move,” Nature, 7205, 705-6(2008). [PDF]

C.N. Salinas and K.S. Anseth, “The Influence of the RGD Peptide Motif and its Contextual Presentation in PEG Gels on Human Mesenchymal Stem Cell Viability,” Journal of Tissue Engineering and Regenerative Medicine, 2, 296-304 (2008). [PDF]

A.E. Rydholm, N.L. Held, D.S.W. Benoit, C.N. Bowman and K.S. Anseth, “Modifying Network Chemistry in Thiol-Acrylate Photopolymers Through Postpolymerization Functionalization to Control Cell-Material Interactions,” Journal of Biomedical Materials Research Part A, 86A, 23-30 (2008). [PDF]

M.C. Cushing, P.D. Mariner, J.T. Liao, E.A. Sims and K.S. Anseth, “Fibroblast Growth Factor Represses Smad-Mediated Myofibroblast Activation in Aortic Valvular Interstitial Cells,” FASEB Journal, 22, 1769-77 (2008). [PDF]

D.N. Shah, S.M. Recktenwall-Work and K.S. Anseth, “The Effect of Bioactive Hydrogels on the Secretion of Extracellular Matrix Molecules by Valvular Interstitial Cells,” Biomaterials, 29, 2060-72 (2008). [PDF]

H.M. Simms, C.N. Bowman and K.S. Anseth, “Using Living Radical Polymerization to Enable Facile Incorporation of Materials in Microfluidic Cell Culture Devices,” Biomaterials, 29, 2228-36 (2008). [PDF]

C.N. Salinas and K.S. Anseth, “The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities,” Biomaterials, 29, 2370-77 (2008).  [PDF]

B.D. Polizzotti, B.D. Fairbanks and K.S. Anseth, “Three-dimensional Biochemical Patterning of Click-based Composite Hydrogels via Thiolene Photopolymerization,” Biomacromolecules, 9, 1084-7 (2008). [PDF]

C.R. Nuttelman, M.A. Rice, A.E. Rydholm, D.N. Shah and K.S. Anseth, “Macromolecular Monomers for the Synthesis of Hydrogel Niches and Their Application in Cell Encapsulation and Tissue Engineering,” Progress in Polymer Science, 33, 167-79 (2008). [PDF]

L.M. Weber, C.Y. Cheung and K.S. Anseth, “Multifunctional pancreatic islet encapsulation barriers achieved via multilayer PEG hydrogels,” Cell Transplantation, 16, 1049-57 (2008). 

2007

D.S.W. Benoit, S.D. Collins and K.S. Anseth, “Multifunctional Hydrogels that Promote Osteogenic Human Mesenchymal Stem Cell Differentiation Through Stimulation and Sequestering of Bone Morphogenic Protein 2,” Advanced Functional Materials, 17, 2085-93 (2007). [PDF] 

M.C. Lawson, C.N. Bowman and K.S. Anseth, “Vancomycin Derivative Photopolymerization to Titanium Kills S. epidermidis,” Clinical Orthopaedics and Related Research, 461, 96-105 (2007).   

M.C. Cushing, J-T. Liao, M.P. Jaeggli and K.S. Anseth, “Material-Based Regulation of the Myofibroblast Phenotype,” Biomaterials, 28, 3378-87 (2007). [PDF]

K.K. Macdonald, C.Y. Cheung and K.S. Anseth, “Cellular Delivery of TGF-beta1 Promotes Osteoinductive Signalling for Bone Regeneration,” Journal of Engineering and Regenerative Medicine, 1, 314-17 (2007). [PDF] 

A.E. Rydholm, S.K. Reddy, K.S. Anseth and C.N. Bowman “Development and Characterization of Degradable Thiol-Allyl Ether Photopolymers,” Polymer, 48, 4589-4600 (2007). [PDF] 

A.W. Watkins, S.L. Southard and K.S. Anseth, “Characterizing Multilaminated Hydrogels with Spatially Varying Network Structure and Solute Loading Using Confocal Laser Scanning Microscopy,” Acta Biomaterialia, 3, 439-448 (2007). [PDF] 

A.E. Rydholm, K.S. Anseth and C.N. Bowman “Effects of Neighboring Sulfides and pH on Ester Hydrolysis in Thiol-Acrylate Photopolymers,” Acta Biomaterialia, 3, 449-455 (2007). [PDF] 

L.M. Weber, K.N. Hayda, K. Haskins and K.S. Anseth, “The Effects of Cell-Matrix Interactions on Encapsulated Beta-Cell Function within Hydrogels Functionalized with Matrix-Derived Adhesive Peptides,” Biomaterials, 28, 3004-11 (2007). [PDF] 

C.N. Salinas, B.B. Cole, A.M. Kasko and K.S. Anseth, “Chondrogenic Differentiation Potential of Human Mesenchymal Stem Cells Photoencapsulated within Poly(ethylene glycol)-Arginine-Glycine-Aspartic Acid-Serine Thiol-Methacrylate Mixed-Mode Networks,” Tissue Engineering, 13, 1025-34 (2007). [PDF

M.C. Cushing and K.S. Anseth, “Hydrogel Cell Cultures,” Science, 316, 1133-34 (2007). [PDF]   

D.S.W. Benoit, M.C. Tripodi, J.O. Blanchette, S.J. Langer, L.A. Leinwand and K.S. Anseth, “Integrin-Linked Kinase Production Prevents Anoikis in Human Mesenchymal Stem Cells,” Journal of Biomedical Materials Research Part A, 81A, 269-278 (2007). [PDF]

M.J. Mahoney and K.S. Anseth, “Contrasting Effects of Collagen and bFGF-2 on Neural Cell Function in Degradable Synthetic PEG Hydrogels,” Journal of Biomedical Materials Research Part A, 81A, 1133-34 (2007). [PDF] 

E.M. Christenson, K.S. Anseth, J.J.P. van den Beucken, C.K. Chan, B. Ercan, J.A. Jansen, C.T. Laurencin, W.J. Li, R. Murugan, L.S. Nair, S. Ramakrishna, R.S. Tuan, T.J. Webster and A.G. Mikos, “Nanobiomaterial Applications in Orthopaedics,” Journal of Orthopaedic Research, 25, 11-22 (2007). [PDF]

J.A. Cooper, W.J. Li, L.O. Bailey, S.D. Hudson, S. Lin-Gibson, K.S. Anseth, R.S. Tuan and N.R. Washburn, “Encapsulated Chondrocyte Response in a Pulsatile Flow Bioreactor,” Acta Biomaterialia, 3, 13-21 (2007). [PDF

D.S.W. Benoit, A.R. Durney and K.S. Anseth, “The Effects of Heparin-functionalized PEG Hydrogels on Three-dimensional Human Mesenchymal Stem Cell Osteogenic Differentiation,” Biomaterials, 28, 66-77 (2007). [PDF]

R.P. Sebra, S.K. Reddy, K.S. Masters, C.N. Bowman and K.S. Anseth, “Controlled Polymerization Chemistry to Graft Architectures that Influence Cell-Material Interactions,” Acta Biomaterialia, 3, 151-161 (2007). [PDF]

M.A. Rice and K.S. Anseth, “Controlling Cartilaginous Matrix Evolution in Hydrogels with Degradation Triggered by Exogenous Addition of an Enzyme,” Tissue Engineering, 13, 683-691 (2007).  [PDF]

K.W. Riddle, H.J. Kong, K.J. Leach, C. Fischbach, C.Y. Cheung, K.S. Anseth and D.J. Mooney, “Modifying the Proliferative State of Target Cells to Control DNA Expression and Identifying Cell Types Transfected In Vivo,” Molecular Therapy, 15, 361-8 (2007). [PDF]

2006

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M.J. Mahoney and K.S. Anseth, “Contrasting Effects of Collagen and bFGF-2 on Neural Cell Function in Degradable Synthetic PEG Hydrogels,” Journal of Biomedical Materials Research,  81A, 269-78(2006). [PDF]

A.E. Rydholm, S.K. Reddy, K.S. Anseth and C.N. Bowman, “Controlling Network Structure in Degradable Thiol-Acrylate Biomaterials to Tune Mass Loss Behavior,” Biomacromolecules, 7, 2827-36 (2006). [PDF]

V.S. Khire, D.S.W. Benoit, K.S. Anseth and C.N. Bowman, “Ultrathin gradient films using thiol-ene polymerizations,” Journal of Polymer Science, Polymer Chemistry, 44, 7027-39 (2006). [PDF]

D.S.W. Benoit, C.R. Nuttelman, S.D. Collins and K.S. Anseth,, “Synthesis and Characterization of a Fluvastatin-Releasing Hydrogel Delivery System to Modulate hMSC Differentiation and Functions for Bone Regeneration,” Biomaterials, 27,  6102-10 (2006). [PDF]

M.A. Rice, J. Sanchez-Adams and K.S. Anseth, “Exogenously Triggered, Enzymatic Degradation of Photopolymerized Hydrogels with Polycaprolactone Subunits:  Experimental Observation and Modelling of Mass Loss Behavior,” Biomacromolecules, 7(6): 1968-1975, (2006). [PDF]

C.Y. Cheung and K.S. Anseth, “Synthesis of immunoisolation barriers that provide localized immunosuppression for encapsulated pancreatic islets,” Bioconjugate Chemistry, 17, 1036-42 (2006). [PDF] 

V.S. Khire, A.W. Harant, A.W. Watkins, K.S. Anseth, and C.N. Bowman, “Ultrathin Patterned Polymer Films on Surfaces using Thiol-ene Polymerizations,” Macromolecules, 39, 5081-86 (2006). [PDF]

R.P. Sebra, K.S. Anseth and C.N. Bowman, “Integrated surface modification of fully polymeric microfluidic devices using living radical photopolymerization chemistry,” Journal of Polymer Science, Polymer Chemistry, 44, 1404-13 (2006). [PDF]

L.M. Weber, J. He, B. Bradley, K. Haskins and K.S. Anseth, "PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta cell microenvironments," Acta Biomaterialia, 2, 1-8 (2006). [PDF]

C.R. Nuttelman, A.M. Kloxin and K.S. Anseth, "Temporal Changes in PEG Hydrogel Structure Influence Human Mesenchymal Stem Cell Proliferation and Matrix Mineralization," Advances in Experimental Medicine and Biology, in press (2006).  [PDF]

C.R. Nuttelman, M.C. Tripodi and K.S. Anseth, “Dexamethasone-Functionalized Gels Induce Osteogenic Differentiation of Encapsulated hMSCs,” Journal of Biomedical Materials Research, 76A, 183-95 (2006). [PDF]

K.T. Haraldsson, J.B. Hutchison, R.P. Sebra, B.T. Good, K.S. Anseth and C.N. Bowman, “3D polymeric microfluidic device fabrication via contact liquid photolithographic polymerization (CLiPP),” Sensors and Actuators B, 113, 454-60 (2006). [PDF]

D.S.W. Benoit, A.R. Durney and K.S. Anseth, "Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation," Tissue Engineering, 12, 1663-1673 (2006). [PDF]

M.J. Mahoney and K.S. Anseth, “ Three-Dimensional Growth and Function of Neural Tissue in Degradable Polyethylene Glycol Hydrogels,” Biomaterials, 27, 2665-74 (2006). [PDF]

C.R. Nuttelman, D.S.W. Benoit, M.C. Tripodi and K.S. Anseth, “The Effects of Ethylene Glycol Methacrylate Phosphate in PEG Hydrogels on Mineralization and Viability of Encapsulated hMSCs,” Biomaterials, 27, 1377-1386 (2006). [PDF] 

R.P. Sebra, K.S. Masters, C.Y. Cheung, C.N. Bowman and K.S. Anseth, “Detection of Antigens in  Biologically Complex Fluid with Photografted Whole Antibodies,” Analytical Chemistry, 78, 3144-51 (2006). [PDF] 

2005

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J.B. Hutchison, P.F. Stark, C.J. Hawker, and K.S. Anseth, “Polymerizable Living Free Radical Initiators as a Platform to Synthesize Functional Networks,” Chemistry of Materials, 17, 4789-97 (2005). [PDF]

D.S.W. Benoit and K.S. Anseth, “Heparin Functionalized PEG Hydrogels that Modulate Protein Adsorption for hMSC Adhesion and Differentiation,” Acta Biomaterialia, 1, 461-470 (2005). [PDF]

S.K. Reddy, K.S. Anseth, and C.N. Bowman, “Modeling of Network Degradation in Mixed Step-Chain Growth Polymerizations,” Polymer, 46, 4212-22 (2005). [PDF]

C.R. Nuttelman, M.C. Tripodi, and K.S. Anseth, “Synthetic Hydrogel Niches that Promote hMSC Viability,” Matrix Biology, 24, 208-18 (2005). [PDF]

M.C. Cushing, K.S. Masters, L.A. Leinwand, and K.S. Anseth, “Serum Deprivation Improves Seeding and Repopulation of Acellular Matrices with Valvular Interstitial Cells,” Journal of Biomedical Materials Research, 75A, 232-41 (2005). [PDF]

S.K. Reddy, R.P. Sebra, K.S. Anseth, and C.N. Bowman, “Living Radical Photopolymerization Induced Grafting on Thiol-Ene Based Substrates,” Journal of Polymer Science, Part A:  Polymer Chemistry, 43, 2134-44 (2005). [PDF]

D.S.W. Benoit and K.S. Anseth, “The Effect on Osteoblast Function of Colocalized RGD and PHSRN Epitopes on PEG Surfaces,” Biomaterials, 26, 5209-20 (2005).

H.S. Simms, C.M.  Brotherton, B.T. Good, R.H. Davis, K.S. Anseth, and C.N. Bowman, “In Situ Fabrication of Macroporous Polymer Networks within Microfluidic Devices by Living Radical Photopolymerization and Leaching,” Lab on a Chip, 5, 151-57 (2005). [PDF]

A.E. Rydholm, C.N. Bowman, and K.S. Anseth, “Degradable Thiol-Acrylate Photopolymers: Polymerization and Degradation Behavior of an In Situ Forming Biomaterial,” Biomaterials, 26, 4495-506 (2005). [PDF]

S.J. Bryant, J.A. Arthur, and K.S. Anseth, “Incorporation of Tissue-Specific Molecules Alters Chondrocyte Metabolism and Gene Expression in Photocrosslinked Hydrogels,” Acta Biomaterialia, 1, 243-52 (2005). [PDF]

A.W. Watkins and K.S. Anseth, “Investigation of Molecular Transport and Distributions in Poly(ethylene glycol) Hydrogels with Confocal Laser Scanning Microscopy,” Macromolecules, 38, 1326-34 (2005). [PDF]

T.M. Lovestead, J.A. Burdick, K.S. Anseth, and C.N. Bowman, “Understanding Multivinyl Monomer Photopolymerization Kinetics through Modeling and GPC Investigation of Degradable Networks,” Polymer, 16, 6226-34 (2005). [PDF]

K.S. Masters, D.N. Shah, L.A. Leinwand, and K.S. Anseth, Crosslinked Hyaluronan Scaffolds as a Biologically Active Carrier for Valvular Interstitial Cells,” Biomaterials, 26, 2517-25 (2005). [PDF]

2004

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J. B. Hutchison, A. Lindquist and K.S. Anseth, “Off-Lattice Simulation of Multifunctional Monomer Polymerizations: Effects of Monomer Mobility, Structure, and Functionality on Structural Evolution at Low Conversion,” Journal of Physical Chemistry B, 108, 11097-11104 (2004). [PDF]

D.J. Quick, K.K. Macdonald and K.S. Anseth, “Delivering DNA from Photocrosslinked, Surface-eroding Polyanhydrides,” Journal of Controlled Release, 97, 333-43 (2004). [PDF]

J.B. Hutchison, K.T. Haraldsson, B.T. Good, R.P. Sebra, N. Luo, K.S. Anseth and C.N. Bowman, “Robust Polymer Microfluidic Device Fabrication Via Contact Liquid Photolithographic Polymerization (CLiPP),” Lab on a Chip, 4, 658-62 (2004). [PDF]

J.B. Hutchison, A.S. Lindquist and K.S. Anseth, “Experimental Characterization of Structural Features during Radical Chain Homopolymerization of Multifunctional Monomers Prior to Macroscopic Gelation: Application to Methacrylic Anhydride,” Macromolecules, 37, 3823-31 (2004). [PDF]

S.J. Bryant, K.A. Davis-Arehart, N. Luo, R.K. Shoemaker, J.A. Arthur and K.S. Anseth, “Synthesis and Characterization of Photopolymerized Multifunctional Hydrogels: Water-soluble Poly(vinyl alcohol) and Chondroitin Sulfate Macromers for Chondrocyte Encapsulation,” Macromolecules, 37, 6726-33 (2004). [PDF]

K.S. Masters, D.N. Shah, G. Walker, L.A. Leinwand and K.S. Anseth, “Designing Scaffolds for Valvular Interstitial Cells: Cell Adhesion and Function on Naturally-Derived Materials,” Journal of Biomedical Materials Research, 71A, 172-80 (2004). [PDF]

M.A. Rice and K.S. Anseth, “Encapsulating Chondrocytes in Copolymer Gels: Bimodal Degradation Kinetics Influence Cell Phenotype and Extracellular Matrix Development,” Journal of Biomedical Materials Research, 70A, 560-68 (2004). [PDF]

S.J. Bryant, T.T. Chowdhury, K.S. Anseth, D.A. Lee and D.L. Bader, “Crosslinking Density Influences the Morphology of Chondrocytes Photoencapsulated in PEG Hydrogels During the Application of Compressive Strain,” Journal of Orthopaedic Research, 22, 1143-49 (2004). [PDF]

S.J. Bryant, R.J. Bender, K.L. Durand and K.S. Anseth, “Encapsulating Chondrocytes in Degrading PEG Hydrogels with High Modulus: Engineering Gel Structural Changes to Facilitate Cartilaginous Tissue Production,” Biotechnology and Bioengineering, 86, 747-55 (2004). [PDF]  

G.A. Walker, K.S. Masters, D.N. Shah, K.S. Anseth and L.A. Leinwand, “Valvular Myofibroblast Activation by TGF-beta: Implications for Pathological ECM Remodeling in Heart Valve Disease,” Circulation Research, 95, 253-60 (2004). [PDF]

P.J. Martens, C.N. Bowman and K.S. Anseth, “Degradable Networks Formed from Multifunctional Poly(Vinyl Alcohol) Macromers: Comparison of Results from a Generalized Bulk-Degradation Model for Polymer Networks and Experimental Data,” Polymer, 45, 3377-3387 (2004). [PDF]

D.J. Quick and K.S. Anseth, “DNA Delivery from Photocrosslinked PEG Hydrogels: Encapsulation Efficiency, Release Profiles, and DNA Quality,” Journal of Controlled Release, 96(2), 341-51 (2004). [PDF]

C.R. Nuttelman, M.C. Tripodi and K.S. Anseth,In Vitro Osteogenic Differentiation of Human Mesenchymal Stem Cells Photoencapsulated in PEG Hydrogels,” Journal of Biomedical Materials Research, 68A(4), 773-82 (2004). [PDF]

S.J. Bryant, T.T. Chowdhury, D.A. Lee, D.L. Bader and K.S. Anseth, “Crosslinking Density Influences Chondrocyte Metabolism in Dynamically Loaded Photocrosslinked PEG Hydrogels,” Annals of Biomedical Engineering, 32, 407-17, (2004).  [PDF]

2003

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M.A. Randolph, K.S. Anseth and M.J. Yaremchuk, “Tissue Engineering of Cartilage,” Clinics in Plastic Surgery, 30, 519-37 (2003).

D.J. Quick and K.S. Anseth, “Gene Delivery in Tissue Engineering: A Photopolymer Platform to Co-encapsulate Cells and Plasmid DNA,” Pharmaceutical Research, 20, 1730-37 (2003). [PDF]

N. Luo, A.T. Metters, J.B. Hutchison, C.N. Bowman, and K.S. Anseth, “A Methacrylated Photoinferter as a Chemical Basis for Microlithography: Micropatterning Based on Photo-Grafting Polymerization,” Macromolecules, 36, 6739-45 (2003). [PDF]

S.J. Bryant, K.L. Durand and K.S. Anseth, “Manipulations in Hydrogel Chemistry Control Photoencapsulated Chondrocyte Behavior and their Extracellular Matrix Production,” Journal of Biomedical Materials Research, 67, 1430-36 (2003). [PDF]

J. Owens, K.S. Anseth and T.W. Randolph, “Mechanism of Microparticle Formation in the Compressed Antisolvent Precipitation and Photopolymerization Process,” Langmuir, 19, 3926-34 (2003). [PDF]

A.W. Watkins and K.S. Anseth, “Copolymerization of Photocrosslinkable Anhydride Monomers for Use as a Biodegradable Bone Cement,” Journal of Biomaterials Science, Polymer Edition, 14, 267-78 (2003).

J.A. Burdick, T.M. Lovestead and K.S. Anseth, “Kinetic Chain Lengths in Highly Crosslinked Networks Formed by the Photoinitiated Polymerization of Degradable Divinyl Monomers: A GPC Investigation,” Biomacromolecules, 4, 149-56 (2003). [PDF]

K.A. Davis, J.A. Burdick and K.S. Anseth, “Photoinitiated Crosslinked Degradable Copolymer Networks for Tissue Engineering Applications,” Biomaterials, 24, 2485-95 (2003). [PDF]

A.K. Poshusta, J.A. Burdick, D.J. Mortisen, R.F. Padera, D. Ruehlman, M.J. Yaszemski and K.S. Anseth, “Histocompatibility of Photocrosslinked Polyanhydrides:  A Novel In Situ Forming Orthopaedic Biomaterial,” Journal of Biomedical Materials Research, 64A, 62-69 (2003). [PDF]

P.J. Martens, S.J. Bryant and K.S. Anseth, “Tailoring the Degradation of Hydrogels Formed from Multivinyl Poly(ethylene glycol) and Poly(vinyl alcohol) Macromers for Cartilage Tissue Engineering,” Biomacromolecules, 4, 283-92 (2003). [PDF]

S.J. Bryant and K.S. Anseth, “Controlling the Spatial Distribution of ECM Components in Degradable PEG Hydrogels for Tissue Engineering Cartilage,” Journal of Biomedical Materials Research, 64A, 70-79 (2003). [PDF] 

2002

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K.A. Davis and K.S. Anseth, “Controlled Release from Crosslinked Degradable Networks,” Critical Reviews in Therapeutic Drug Carrier Systems, 19, 385-423 (2002).

J.A. Burdick, R.F. Padera, J.V. Huang and K.S. Anseth, “An Investigation of the Cytotoxicity and Histocompatibility of In Situ Forming Lactic Acid Based Orthopaedic Biomaterials,” Journal of Biomedical Materials Research, Applied Biomaterials, 63, 484-91 (2002). [PDF]

J.A. Burdick, D. Frankel, W.S. Dernell and K.S. Anseth, “An Initial Investigation of Photocurable 3-Dimensional Lactic Acid Based Scaffolds in a Critical-Sized Cranial Defect,” Biomaterials, 24, 1613-20 (2003). [PDF]

J.A. Burdick, M.N. Mason, A.D. Hinman, K. Thorne and K.S. Anseth, “Delivery of Osteoinductive Growth Factors from Degradable PEG Hydrogels Influences Osteoblast Differentiation and Mineralization,” Journal of Controlled Release, 83, 53-63 (2002). [PDF]

P. Martens, T. Holland and K.S. Anseth, “Synthesis and Characterization of Degradable Hydrogels Formed from Acrylate Modified Poly(Vinyl Alcohol) Macromers,” Polymer, 43, 6093-6100 (2002). [PDF]

A.K. Poshusta, C.N. Bowman and K.S. Anseth, “Application of a Kinetic Gelation Simulation to the Characterization of In Situ Crosslinking Biomaterials,” Journal of Biomaterials Science, Polymer Edition, 13, 797-815 (2002).

J.A. Burdick and K.S. Anseth, “Photoencapsulation of Osteoblasts in Injectable RGD-Modified PEG Hydrogels for Bone Tissue Engineering Applications,” Biomaterials, 23, 4315-23 (2002). [PDF]

S.J. Bryant and K.S. Anseth, “Hydrogel Properties Influence ECM Production by Chondrocytes Photoencapsulated in Poly(ethylene glycol) Hydrogels,” Journal of Biomedical Materials Research, 59, 63-72 (2002). [PDF]

K.S. Anseth and J.A. Burdick, “New Directions in Photopolymerizable Biomaterials,” MRS Bulletin, 1-7, (Feb., 2002).

C.R. Nuttelman, S.M. Henry and K.S. Anseth, “Synthesis and Characterization of Photocrosslinkable, Degradable Poly(vinyl alcohol)-based Tissue Engineering Scaffolds,” Biomaterials, 23, 3617-26 (2002). [PDF]

J.L Owens, K.S. Anseth and T.W. Randolph, “Compressed Antisolvent Precipitation and Polymerization to Form Highly Crosslinked Polymer Particles,” Macromolecules, 35, 4289-96 (2002). [PDF]

N. Luo, J.B. Hutchison, K.S. Anseth and C.N. Bowman, “Synthesis of A Novel Methacrylic Monomer-Iniferter and Its Application in Surface Photo-Grafting on Crosslinked Polymer Substrates, Journal of Polymer Science Part A: Polymer Chemistry, 40, 1885-91 (2002). [PDF]

N. Luo, J.B. Hutchison, K.S. Anseth and C.N. Bowman, “Surface-Initiated Photopolymerization of Poly(ethylene glycol) Methyl Ether Methacrylate on a Diethyldithiocarbamate-Mediated Polymer Substrate,” Macromolecules, 35, 2487-93 (2002). [PDF]

K.S. Anseth, A.T. Metters, S.J. Bryant, P.J. Martens, J.H. Elisseeff and C.N. Bowman, “In Situ Forming Degradable Networks and Their Application in Tissue Engineering and Drug Delivery,” Journal of Controlled Release, 78, 199-209 (2002). [PDF]

2001

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L. Liew, W. Zhang, L. An, S. Shah, R. Luo, Y. Liu, T. Cross, M.L. Dunn, V. Bright, J.W. Daily, R. Raj and K.S. Anseth, “Ceramic MEMS: New Materials, Innovative Processing and Future Applications,” American Ceramic Society Bulletin, 80, 25-30 (2001). [PDF]

J.A. Burdick, M.N. Mason and K.S. Anseth, “In Situ Forming Lactic Acid Based Orthopaedic Biomaterials: Influence of Oligomer Chemistry on Osteoblast Attachment and Function,” Journal of Biomaterials Science, Polymer Edition, 12, 1253-65 (2001).

C.R. Nuttelman, D.J. Mortisen, S.M. Henry and K.S. Anseth, “Attachment of Fibronectin to Poly(Vinyl Alcohol) Hydrogels Promotes NIH3T3 Cell Adhesion, Proliferation, and Migration,” Journal of Biomedical Materials Research, 57, 217-223 (2001). [PDF]

J.B. Hutchison and K.S. Anseth, “An Off-Lattice Approach to Simulate Radical Chain Polymerization of Tetrafunctional Monomers,” Macromolecular Theory and Simulations, 10, 600-607 (2001). [PDF]

M. N. Mason, A.T. Metters, C.N. Bowman and K.S. Anseth, “Predicting Controlled-Release Behavior of Degradable PLA-b-PEG-b-PLA Hydrogels,” Macromolecules, 34, 4630-35 (2001). [PDF]

J.A. Burdick, L.M. Philpott and K.S. Anseth, “Synthesis and Characterization of Tetrafunctional Lactic Acid Oligomers: A Potential In Situ Forming Orthopaedic Biomaterial,” Journal of Polymer Science, A, Polymer Chemistry, 39, 683-92 (2001). [PDF]

P. Martens, A.T. Metters, K.S. Anseth and C.N. Bowman, “A Generalized Bulk-Degradation Model for Hydrogel Networks Formed from Multi Vinyl Cross-linking Molecules,” Journal of Physical Chemistry B, 105, 5131-38 (2001). [PDF]

A.T. Metters, C.N. Bowman and K.S. Anseth, “A Statistical Kinetic Model for the Bulk Degradation of PLA-b-PEG-b-PLA Hydrogel Networks:  Incorporating Network Non-Idealities,” Journal of Physical Chemistry B, 105, 8069-8076 (2001). [PDF]

J.A. Burdick, A.J. Peterson and K.S. Anseth, “Conversion and Temperature Profiles During the Photoinitiated Polymerization of Thick Orthopaedic Biomaterials,” Biomaterials, 22, 1779-86 (2001). [PDF]

A.K. Poshusta and K.S. Anseth, “Photopolymerized Biomaterials for Applications in the Temporomandibular Joint,” Cells Tissues Organs, 169, 272-78 (2001).

D.J. Quick and K.S. Anseth, “Polymerizations of Multifunctional Anhydride Monomers to Form Highly Crosslinked Degradable Networks,” Macromolecular Rapid Communications, 22, 564-72 (2001). [PDF]

A.T. Metters, C.N. Bowman and K.S. Anseth, “Verification of Scaling Laws for Degrading PLA-b-PEG-b-PLA Hydrogels,” AIChE Journal, 47, 1432-37 (2001). [PDF]

S.J. Bryant and K.S. Anseth, “The Effect of Scaffold Thickness on Tissue Engineered Cartilage in Photocrosslinked Poly(ethylene oxide) Hydrogels,” Biomaterials, 22, 619-26 (2001). [PDF]

2000

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A.T. Metters, K.S. Anseth and C.N. Bowman, “A Statistical Kinetic Model for the Bulk-Degradation of PEG-b-PLA Hydrogel Networks,” Journal of Physical Chemistry B, 104, 7043-49 (2000). [PDF]

P. Martens and K.S. Anseth, “Characterization of Hydrogels Formed from Acrylate Modified Poly (Vinyl Alcohol) Macromers,” Polymer, 41, 7715-22 (2000). [PDF]

A.K. Burkoth, J.A. Burdick and K.S. Anseth, “Surface and Bulk Modifications to Photocrosslinked Polyanhydrides to Control Degradation Behavior,” Journal of Biomedical Materials Research, 51, 352-59 (2000). [PDF]

A.K. Burkoth and K.S. Anseth, “A Review of Photocrosslinked Polyanhydrides: In Situ Forming Degradable Networks,” Biomaterials, 21, 2395-2404 (2000). [PDF]

J. Elisseeff, W. McIntosh, K. Anseth, S. Riley, P. Ragan and R. Langer, “Photoencapsulation of Chondrocytes in Poly(Ethylene Oxide)-Based Semi-Interpenetrating Networks,” Journal of Biomedical Materials Research, 51, 164-171 (2000). [PDF]

S. Lu and K.S. Anseth, “Release Behavior of High Molecular Weight Solutes From Poly(ethylene glycol)-Based Degradable Networks,” Macromolecules, 33, 2509-2515 (2000). [PDF]

A.T. Metters, K.S. Anseth and C.N. Bowman, “Fundamental Studies of a Novel, Biodegradable PEG-b-PLA Hydrogel,” Polymer, 41, 3993-4004 (2000). [PDF]

S. Lu, W.F. Ramirez and K.S. Anseth, “Photopolymerized, Multilaminated Matrix Devices with Optimized Nonuniform Initial Concentration Profiles to Control Drug Release,” Journal of Pharmaceutical Sciences, 89, 45-51 (2000). [PDF]

J.S. Young, K.D. Gonzales and K.S. Anseth, “Photopolymers in Orthopedics:  Characterization of Novel Crosslinked Polyanhydrides,” Biomaterials, 21, 1181-88 (2000). [PDF]

S.J. Bryant, C.R. Nuttelman and K.S. Anseth, “Cytocompatibility of UV and visible light photoinitiating systems on cultured NIH/3T3 fibroblasts,” Journal of Biomaterials Science. Polymer Edition/i>, 11, 439-57 (2000).

 

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