The outstanding research conducted by the faculty and students in our department has lead to the following successful start up companies:
ALD Nanosolutions (Steven George and Al Weimer) helps customers accelerate their product innovation. ALDN's proprietary Particle ALD coating technology, which can apply designed coatings at the nanometer scale on particles of any size, creates enormous commercial opportunity for new materials development and integration. In addition, Polymer ALD forms nanocoatings on polymer films, where ALDN is developing continuous roll to roll ALD coating capability. ALDN's multi-layer ALD films will fundamentally shift commercial polymer coating processes to lower cost, higher performance films.
BaroFold Inc. (Theodore Randolph) is a company that uses high-pressure technology developed in the Randolph laboratories to disaggragate and fold therapeutic proteins to their biologically active three dimensional structure.
Biota Technology (Ryan Gill) is a venture-backed startup that delivers novel software and information services to industrial markets. The company leverages low cost DNA sequencing and cloud computing with their innovations in microbiome software and data science to solve large, unmet industrial challenges.
Colorado Photopolymer Solutions (Chris Bowman) provides high quality materials and technology development in all areas of photopolymerization. The company develops and manufactures custom photocurable formulations and monomers tailored to meet the needs of individual companies and applications. They also provide consulting services in all areas of photopolymerizations for development of monomers, formulations, specialty polymers and materials, and analytical characterization.
Ion Engineering (Doug Gin and Rich Noble) is a start-up company formed by former students and postdocs from the Noble and Gin research groups. This company focuses on using ionic liquid-amine solutions for large-scale CO2 removal from industrial combustion exhaust.
Mosaic Biosciences (Kristi Anseth and Chris Bowman) is advancing a fundamentally new class of synthetic materials to support native tissue regeneration. Mosaic expects to significantly impact the field of tissue regeneration, including applications in wound healing, bone regeneration, cartilage repair, stem cell therapy, and dermal fillers.
Nanoly Bioscience, Inc. (Kristi Anseth) is working to bypass the vaccine “cold chain,” which is a refrigerated system of transporting and storing vaccines within the narrow temperature range of 35 to 45 degrees Fahrenheit. The strict temperature limitations are necessary to prevent vaccine proteins from denaturing, rendering the vaccines inactive. Keeping vaccines at a certain temperature restricts their ability to be delivered to remote areas of the world where there is no electricity or refrigeration – areas that could benefit from vaccines the most. “We are developing a polymer that can be blended with vaccines to prevent spoilage without refrigeration,” says Balaji Sridhar. “The polymer is non-toxic, and exposure to light will disassemble the polymer so that the vaccine is ready for delivery.”
OPX Biotechnologies, Inc. (Ryan Gill) was a Colorado-based bioproducts company using proprietary bioengineering technology to convert renewable feedstocks into biofuels and green chemistry products. The company was acquired by Cargill in 2015. The OPX EDGE - Efficiency Directed Genome Engineering - technology platform enabled rapid, rational, and robust optimization of microbes and bioprocesses. Compared to petroleum-based alternatives, OPX EDGE bioprocesses delivered equivalent product performance with improved sustainability at lower cost. Using the EDGE platform, OPX produced multiple biofuel and green chemistry products at laboratory scale from several different renewable feedstocks.
PRAAN Biosciences (Anushree Chatterjee and Prashant Nagpal) utilizes a single-molecule Quantum Molecular Sequencing (QM-Seq) technique using unique “electronic and optical fingerprints” to directly determine the sequence of single molecules of RNA, DNA and other biomolecules.
RxKinetix (Theodore Randolph) is a drug delivery company which was sold to Endo Pharmaceuticals.
SFC Fluidics (Rich Noble) This technology focuses on manufacturing an electrochemical pump with no moving parts. This object is useful for a number of applications of controlled delivery, including drugs.
Sundrop Fuels Inc. (Alan Weimer) is a solar gasification-based renewable energy company out of Louisville, CO.
VitriVax, Inc. (Theodore Randolph) is a vaccine stabilization company formed in 2014.
Balaji Sridhar is a CU Boulder Chemical Engineering PhD candidate halfway through two years of the Medical Scientist Training Program, a joint effort between CU campuses in Denver and Boulder.
Ten active companies have been created since 1997 based on technologies invented wholly or in part by CU chemical and biological engineering students and their faculty supervisors.
Recognizing the revenue potential of CU-licensed science moving to the commercial market, CU is looking at how to best maximize proceeds from technology transfer. The university plans to soon seek bids from consultants to help with this process.