research

Pat Hume publishes "Strategies to Reduce Dendritic Cell Activation through Functional Biomaterial Design" in Biomaterials

August 20, 2012

Pat Hume showed that immunosuppressive factors maintain their activity when tethered to a hydrogel and reduce markers of dendritic cell activation. The figure shows reduced levels of IL-12 expression in dendritic cells seeded upon hydrogels functionalized with immunosuppressive proteins TGF-B1 and IL-10.

Cole DeForest publishes "Photoreversible Patterning of Biomolecules within Click-Based Hydrogels" in Angewandte Chemie

August 20, 2012

Cole DeForest shows the addition and removal of biologically active peptides using two orthogonal photochemistries. His work is highlighted on the cover of Angewandte Chemie-International Edition.

C.A. DeForest and K.S. Anseth, "Photoreversible Patterning of Biomolecules within Click-Based Hydrogels," Angewandte Chemie-International Edition, 51 (8), 1816-1819 (2012).

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