June 11, 2015
Noteworthy Chemistry, a weekly publication by the ACS that highlights specific articles from a broad range of literature, selected two of our articles for their feature. Photocontrolled Nanoparticles for On-Demand Release of Proteins was highlighted in
April 14, 2015
In this work, Jen (now at Ohio State) and Emi (now at Seattle Children's Hospital) investigate the effect of cancer drugs on matrix metalloproteinase (MMP) and metabolic activity of melanoma cells at various stages of metastasis. Their findings suggest that current clinical drugs can upregulate MMP activity, causing increased metastatic cell migration. Check out the pre-print publication here!
October 11, 2014
April 24, 2014
Samir Singh showed scaffold modulus and peptide functionalization affected tumor cell migration in a 3D synthetic matrix. His paper, entitled "A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration" appears in Biomaterials Science.
March 31, 2014
Daniel McKinnon and Dylan Domaille (postdoc in Jen Cha's lab) "Bis-Aliphatic Hydrazone-Linked Hydrogels Form Most Rapidly at Physiological pH: Identifying the Origin of Hydrogel Properties with Small Molecule Kinetic Studies" in Chemistry of Materials.