News

Kyle Kyburz publishes "Three-dimensional hMSC motility within peptide-functionalized PEG-based hydrogels of varying adhesivity and crosslinking density" in Acta Biomaterialia

February 25, 2013

Kyle Kyburz demonstrated the importance of adhesive ligand interactions and network crosslinking density on hMSC migration and spreading.

K.A. Kyburz and K.S. Anseth, "Three-dimensional hMSC motility within peptide-functionalized PEG-based hydrogels of varying adhesivity and crosslinking density," Acta Biomaterialia (2013).

5 Anseth Group members will be presenting their work at the Rocky Mountain Medical Technologies Conference

February 22, 2013

Chun Yang will be presenting a poster explaining her work on hMSC osteogenesis, Zach Stephens will present his work on VIC activation on dynamic substrates, Abigail Bernard will present her work on the effect of aggregate dimensionality on β-cell signaling and function,

Nava Gandavarapu earns Anseth Group February Employee of the Month

February 1, 2013

Nava successfully defended his thesis January 31st demonstrating the capabilities of hydrogels to enchance osteogenic differentiation. Congratulations Nava!

Daniel McKinnon publishes "Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons" in Biomaterials Science

January 28, 2013

Daniel McKinnon demonstrated the 3D culture of motor neurons in engineered PEG hydrogels that enabled good viability and robust axon extention. He further demonstrated the importance of ECM-mimic peptides to the viability of dissociated cells and the role of hydrogel modulus and crosslinker in axon extension.

Chelsea Kirschner publishes "Hydrogels in Healthcare: From Static to Dynamic Microenvironments" in Acta Materialia

January 23, 2013

Chelsea Kirschner publishes a nice review of dynamic hydrogel environments titled "Hydrogels in Healthcare: From Static to Dynamic Microenvironments" in Acta Materialia. She summarized current progress in light, enxyme, electric field, temperature, and pH sensitive hydrogels for biomedical applications.

Kelly Schultz earns Anseth Group Employee of the Month

January 10, 2013

Kelly Schultz wrote an NSF grant that was funded and resulted in our lab getting a shiny new rheometer. In addition, she recently published her first paper in the Anseth group and has been helping everyone with their rheological experiments.

Boulder County Business Report highlights the Anseth Group research as the top "discovery that could change the world"

December 21, 2012

Boulder County Business Report published their top "10 discoveries that could change the world" and the Anseth Group's work in tissue engineering made number 1. Check it out at http://www.bcbr.com/article/20121207/PUBLICATIONS06/121129941/0/SEARCH.

Malar Azagarsamy publishes "Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds" in ACS Macro Letters

December 17, 2012

Malar Azagarsamy wrote an fantastic review of bioorthogonal click chemistry covering thiol-ene, click, and Michael addtions.

M.A Azagarsamy and K.S. Anseth, "Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds," ACS Macro Letters, 2, 5-9 (2013)

Kelly Schultz publishes "Monitoring Degradation of Matrix Metalloproteinases-Cleavable PEG Hydrogels via Multiple Particle Tracking Microrheology" in Soft Matter

December 17, 2012

Kelly Schultz showed that thiol-ene step-growth hydrogels degrade homogeneously when exposed to enzymes.

K.M. Schultz and K.S. Anseth, "Monitoring Degradation of Matrix Metalloproteinases-Cleavable PEG Hydrogels via Multiple Particle Tracking Microrheology," Soft Matter (2012).

Chun Yang publishes "Cell-Mediated Delivery of Glucocorticoids from Thiol-Ene Hydrogels" in Journal of Controlled Release

December 17, 2012

Chun Yang showed controlled release of Dexamethasone led to osteogenic differentiation of human mesenchymal stem cells.

C. Yang, P.D. Mariner, J.N. Nahreini, and K.S. Anseth, "Cell-Mediated Delivery of Glutocorticoids from Thiol-Ene Hydrogels," Journal of Controlled Release, 162, 612-618 (2012).

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