September 25, 2012
Kelly Pollock, Quinn Flemming, and Daniel McKinnon spent the weekend in Breckenridge sharing their research with other NIH Pharmaceutical Biotechnology Training grant recipients. Kelly presented her work on VIC differentiation, Quinn his work on patterning the nervous system, and Dan his work on motor neuron encapsulation.
September 6, 2012
Tissue Engineering Part C selects a Featured Article each month that represents groundbreaking research in regenerative medicine. Abby's paper entitled "A Microwell Culture Platform for the Aggregation of Pancreatic Beta-Cells" recieved this honor in Volume 18 Issue 8. Congratulations Abby!
September 4, 2012
Abby Bernard showed that pancreatic beta-cells aggregates could be formed in photopolymerized microwell devices. These cell aggregates secreted significantly more insulin per cell than dispersed cells.
A.B. Bernard, C.C. Lin, and K.S. Anseth, "A Microwell Culture Platform for the Aggregation of Pancreatic Beta-Cells," Tissue Engineering Part C-Methods, 18 (8), 583-592 (2012).
September 3, 2012
Mark Tibbitt, who recently defended, wins Anseth Group Employee of the Month for his outstanding work in materials research. He is currently wrapping up loose ends and researching postdoc positions so please contact him if you have a good opportunity.
August 30, 2012
Recent Anseth Group Alum Josh McCall showed the that proteins encapsulated in hydrogels formed by radical-mediated thiol-ene polymerization maintain significantly more activity than those encapsulated in gels formed by more traditional acrylate polymerization.
J.D. McCall and K.S. Anseth, "Thiol-Ene Photopolymerizations Provide a Facile Method to Encapsulate Proteins and Maintain their Bioactivity," Biomacromolecules, 13 (8), 2410-2417 (2012).
August 22, 2012
Sarah Gould showed VICs significantly upregulate alpha-SMA when plated on gels functionalized elastin and collagen mimic peptides as compared with the canonical fibronectin mimic peptide RGD. Furthermore, Sarah showed that alpha-SMA expression, indicative of a disease phenotype, is downregulated in VICs plated on gels versus though on tissue culture plastic.
August 21, 2012
The Materials Research Society Mid-Career Researcher Award, endowed by Aldrich Materials Science, recognizes exception achievements in materials research made by mid-career professionals. Congratulations Kristi!
August 21, 2012
Malar Azagarsamy demonstrated the light-mediated release of protein from PEG nanogels. He showed the release of active ALP in vitro and that nanogels enter the cell when coupled to TAT peptides.
M.A. Azagarsamy, D.L. Alge, S.J. Radhakrishnan, M.W. Tibbitt, and K.S Anseth, "Photocontrolled Nanoparticles for On-Demand Release of Proteins," Biomacromolecules, 13 (8), 2219-2224 (2012).
August 20, 2012
Mark Tibbitt defended his thesis entitled "Fundamental characterization and application of photodegradable hydrogels: Spatiotemporal control of the cellular microenvironment" to a packed house. He will be working in the Anseth lab for the next couple months wrapping up unfinished projects and is currently applying for postdocs.
August 20, 2012
12 members of the Anseth group traveled to Jackson, WY for the Polymer Networks 2012 conference. Daniel Alge, Kyle Kyburz, Mark Tibbitt, Chelsea Magin, Daniel McKinnon, and Malar Azagarsamy gave oral presentations and Kelly Pollock, Kelly Trowbridge, Emi Tokuda, Jennifer Leight, Katie Lewis, and Emily Matherly presented posters.