News

Kristi Anseth wins the Inaugural Materials Research Society Mid-Career Reseacher Award

August 21, 2012

The Materials Research Society Mid-Career Researcher Award, endowed by Aldrich Materials Science, recognizes exception achievements in materials research made by mid-career professionals. Congratulations Kristi!

Malar Azagarsamy publishes "Photocontrolled Nanoparticles for On-Demand Release of Proteins" in Biomacromolecules

August 21, 2012

Malar Azagarsamy demonstrated the light-mediated release of protein from PEG nanogels. He showed the release of active ALP in vitro and that nanogels enter the cell when coupled to TAT peptides.

M.A. Azagarsamy, D.L. Alge, S.J. Radhakrishnan, M.W. Tibbitt, and K.S Anseth, "Photocontrolled Nanoparticles for On-Demand Release of Proteins," Biomacromolecules, 13 (8), 2219-2224 (2012).

Mark Tibbitt defended thesis

August 20, 2012

Mark Tibbitt defended his thesis entitled "Fundamental characterization and application of photodegradable hydrogels: Spatiotemporal control of the cellular microenvironment" to a packed house. He will be working in the Anseth lab for the next couple months wrapping up unfinished projects and is currently applying for postdocs.

Anseth group returns from Polymer Networks 2012 in Jackson, WY

August 20, 2012

12 members of the Anseth group traveled to Jackson, WY for the Polymer Networks 2012 conference. Daniel Alge, Kyle Kyburz, Mark Tibbitt, Chelsea Magin, Daniel McKinnon, and Malar Azagarsamy gave oral presentations and Kelly Pollock, Kelly Trowbridge, Emi Tokuda, Jennifer Leight, Katie Lewis, and Emily Matherly presented posters.

Sharon Wang publishes "Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-Mediated Reduction in Substrate Modulus" in PLoS ONE

August 20, 2012

Sharon (Huan) Wang shows that valvular interstitial cells will return to a quiescent phenotype after reducing the modulus of the substrate on which they are plated using the nitrobenzyl photochemistry the Anseth group brought into hydrogels. The figure shows the reduction in alpha smooth muscule actin (green) in gels that have been softened.

Mark Tibbitt wins award for outstanding research at the World Biomaterials Congress in China

August 20, 2012

Mark Tibbitt's work on photodegradable microspheres earns him the Student Award for Outstanding Research in the PhD Category at the 9th World Biomaterials Congress in Chengdu, China.

3 Anseth students receive NIH Training Grants

August 20, 2012

Kelly Pollock, Quinn Flemming, and Daniel McKinnon all earned NIH Training Grants in Pharmaceutical Biotechnology.

Mark Tibbit publishes "Synthesis and Application of Photodegradable Microspheres for Spatiotemporal Control of Protein Delivery" in Journal of Biomedical Materials Research"

August 20, 2012

Mark Tibbitt demonstrated controlled release of protein from photodegradable PEG microspheres. His work earned him the Outstanding Research Winner in the PhD category for the 9th World Biomaterials Congress in China.

M.W. Tibbitt, B.W. Han, A.M. Kloxin, and K.S. Anseth, "Synthesis and Application of Photodegradable Microspheres for Spatiotemporal Control of Protein Delivery," Journal of Biomedical Materials Research Part A, 100A (7), 1647-1654 (2012).

Pat Hume publishes "Strategies to Reduce Dendritic Cell Activation through Functional Biomaterial Design" in Biomaterials

August 20, 2012

Pat Hume showed that immunosuppressive factors maintain their activity when tethered to a hydrogel and reduce markers of dendritic cell activation. The figure shows reduced levels of IL-12 expression in dendritic cells seeded upon hydrogels functionalized with immunosuppressive proteins TGF-B1 and IL-10.

Cole DeForest publishes "Photoreversible Patterning of Biomolecules within Click-Based Hydrogels" in Angewandte Chemie

August 20, 2012

Cole DeForest shows the addition and removal of biologically active peptides using two orthogonal photochemistries. His work is highlighted on the cover of Angewandte Chemie-International Edition.

C.A. DeForest and K.S. Anseth, "Photoreversible Patterning of Biomolecules within Click-Based Hydrogels," Angewandte Chemie-International Edition, 51 (8), 1816-1819 (2012).

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