Chun Yang publishes "Cell-Mediated Delivery of Glucocorticoids from Thiol-Ene Hydrogels" in Journal of Controlled Release

December 17, 2012

Chun Yang showed controlled release of Dexamethasone led to osteogenic differentiation of human mesenchymal stem cells.

C. Yang, P.D. Mariner, J.N. Nahreini, and K.S. Anseth, "Cell-Mediated Delivery of Glutocorticoids from Thiol-Ene Hydrogels," Journal of Controlled Release, 162, 612-618 (2012).

All the Anseth group members thank HHMI for the generous Christmas gift

December 13, 2012

Howard Hughes Medical Institute sent every member of the Anseth group a nice cooking apron decked out with a beer pouch, bottle opener, over mitt, and matching rag. We appreciate the gift and have been using them every evening so thank you Howard!

William Wan earns American Heart Association's postdoctoral fellowship

December 13, 2012

William Wan earned the American Heart Association's prestigous postdoctoral fellowship for his proposal titled "Directing cardiomyocyte phenotype through dynamic, in situ modulation of substrate mechanical properties." Congratulations William!

Anna Herland visiting the Anseth lab from faraway Sweden

December 11, 2012

Anna Herland traveled from Sweden to Boulder to visit the Anseth lab and learn some new techniques.

Anseth Group/BioFrontiers Basketball team ends its season with a loss in the Elite 8 round of the CU IM tournament

December 6, 2012

The Anseth Group/BioFrontiers intramural basketball team ended the intramural season with a 7-1 record and failed to advance to the Final Four to match last season's result. Team roster includes Balaji Sridhar, Daniel McKinnon, Phil Calabrese (Eaton lab), Mark Swartzlander (Bryant lab), Tim Read (Dowell Lab), and Spencer Frebel. The team plans to hit the recruiting trail over the winter, regroup, and take home the title in the Winter Season I tournament that begins in January.

Two Anseth group publications featured as "most read" articles in Biomacromolecules for the Autumn quarter

November 29, 2012

Malar Azagarsamy's paper on photodegradable nanoparticles for intracellular protein delivery and Josh McCall's paper

Mark Tibbitt publishes "Dynamic Microenvironments: The Fourth Dimension" in Science Translational Medicine

November 16, 2012

Mark just published a perspicacious perspective on 4D cellular microenvironments in Science Translational Medicine. Reprint is available here.

M.W. Tibbitt and K.S. Anseth, "Dynamic Microenvironments: The Fourth Dimension," Science Translational Medicine, 4, 160ps24 (2012).

Nava Gandavarapu publishes "Extracellular Matrix Protein Adsorption to Phosphate-Functionalized Gels from Serum Promotes Osteogenic Differentiation of Human Mesenchymal Stem Cells" in Acta Biomaterialia

November 6, 2012

Nava showed that the osteogenic differentiation of hMSCs in hydrogels functionalized with phosphate groups can be attributed to serum protein adsorption.

April Kloxin and Katie Lewis publish "Responsive Culture Platform to Examine the Influence of Microenvironmental Geometry on Cell Function in 3D" in Integrative Biology

November 6, 2012

April, now an assistant professor at University of Delaware, and Katie presented a dynamic culture platform in which microwells are patterned and later connected through cytocompatible photocleavage of a poly(ethylene glycol)-based hydrogel to examine matrix geometry effects on cell fate.

Chelsea Kirschner publishes "In Situ Control of Cell Substrate Microtopographies Using Photolabile Hydrogels" in Small

November 6, 2012

Chelsea demonstrated that human Mesenchymal Stem Cells align along topographies patterned on the surface of photodegradable hydrogels. She further showed that cells will dynamically change their cytoskeletal organization in response to a modified topography.