In this paper, former undergraduate research Michael Nehls and postdoc Adrianne Rosales demonstrate control over release kinetics of a model peptide drug based on a photo-switchable host/guest interaction between azobenzene and cyclodextrin.
This excellent review summarizes many of the techniques used to make reversible hydrogels. Whether the reversibility is in the crosslinks themselves, or in pendant functional groups, these gels have many interesting and exciting properties.
We have four new excellent members of the Anseth lab this year.
In this paper, the authors describe a hydrazone crosslinked hydrogel formed by the reaction of photo-generated aldehydes with pendant hydrazine functionalities. The same reaction is also used to pattern biochemical ligands within the gel.
In her latest publication, recent PhD graduate Kelly Mabry analyzes the differences in gene expression between freshly isolated valvular interstitial cells (VICs) and those cultured on conventional tissue culture plastic, on two-dimensional hydrog