News

Michael and Adrianne report on controlled drug delivery based on host/guest interactions from PEG hydrogels

February 2, 2016

In this paper, former undergraduate research Michael Nehls and postdoc Adrianne Rosales demonstrate control over release kinetics of a model peptide drug based on a photo-switchable host/guest interaction between azobenzene and cyclodextrin. Check it out here!

Adrianne Rosales publishes a review of reversible hydrogel strategies in Nature Reviews Materials

February 2, 2016

This excellent review summarizes many of the techniques used to make reversible hydrogels. Whether the reversibility is in the crosslinks themselves, or in pendant functional groups, these gels have many interesting and exciting properties. Check it out online here.

The Anseth group welcomes Anouk Killaars, Ben Richardson, Brian Aguado, and Jason Silver

January 13, 2016

We have four new excellent members of the Anseth lab this year. Anouk is joining us after a Master's degree at Radboud University Nijmegen in the Netherlands, Jason joined from the MSTP program at the CU Denver medical school, Ben is a first-year student in the chemical engineering department, and Brian is coming fresh off a doctoral degree at Northwestern with Professor Lonnie Shea. Keep an eye out for exciting research coming from these scientists!

Malar and Ian publish "Photoregulated hydrazone-based hydrogel formation for biochemically patterning 3D cellular microenvironments" in ACS Macro Letters

January 13, 2016

In this paper, the authors describe a hydrazone crosslinked hydrogel formed by the reaction of photo-generated aldehydes with pendant hydrazine functionalities. The same reaction is also used to pattern biochemical ligands within the gel. Check it out!

Kelly Mabry publishes "Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype" in Biomaterials

December 21, 2015

In her latest publication, recent PhD graduate Kelly Mabry analyzes the differences in gene expression between freshly isolated valvular interstitial cells (VICs) and those cultured on conventional tissue culture plastic, on two-dimensional hydrogels, and encapsulated within three-dimensional hydrogels. Check it out here!

Two recent articles highlighted in Noteworthy Chemistry feature by ACS

June 11, 2015

Noteworthy Chemistry, a weekly publication by the ACS that highlights specific articles from a broad range of literature, selected two of our articles for their feature. Photocontrolled Nanoparticles for On-Demand Release of Proteins was highlighted in

Kelly Mabry publishes "Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment"

May 28, 2015

In this work, Kelly investigates the effect of dynamic hydrogel stiffening on encapsulated VICs. Check out the article (appearing in the journal Biomaterials) here.

Tobin Brown presents at Excellence in Graduate Polymer Research symposium at ACS

April 27, 2015

Tobin was selected to present at this symposium at the 2015 ACS national meeting in Denver. Check out the official writeup here.

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