 |
Home
> Research Opportunities for Undergrads
> BURST > Available Positions
Listing of Available
Positions
Below are BURST projects
currently available to CU Undergraduates.
Please note that listed
projects do not represent all available projects as many faculty do not
post listings here but expect students to come to them to discuss potential
projects. If you are interested in a particular position, please contact
the faculty member directly.
Posted: April 2, 2008
Project Title: Bionanomaterials for the construction of artificial blood vessels
Project Description:
This project involves the construction of artificial blood vessels (or vascular biografts) using endothelial cells and smooth muscle cells seeded in a collagen-based nano-biocomposite. The goal of this project is to optimize the components in the collagen composite matrix for proper cellular activities and matching biomechanical properties with native blood vessels. Biomechanical property, cell structure and biology in the matrix materials will be characterized.
Requirements:
Knowledge in physiology, cell biology and chemistry are desired.
Department:
Department of Mechanical Engineering (CU-Boulder)
Department of Pediatrics, Cardiology (UCHSC)
Faculty supervisor:
Wei Tan
Contact Information:
wtan@colorado.edu
Posted: April 2, 2008
Project Title: Characterization of biomolecule binding on a PEG-coated nano-biosensor
Project Description:
This project involves thin-film preparation and biomolecule binding characterization on the surface of nanomaterials. The surface of nanomaterials will be modified with antifouling polyethylene glycol (PEG) thin-film using different methods. The PEG chain ends with antibodies specific for a particular analyte in a biological sample such as blood. The goal of the project is to decrease nonspecific binding of biomolecules on the nanomaterials so as to increase the detection accuracy of the analyte specifically bound to the surface of nanomaterials. Herein, nonspecific binding or biomolecules on nanomaterials will be studied using molecules such as albumin and fibrinogen, the most abundant proteins in the blood. Specific binding will be studied using strepavidin-biotin.
Requirements:
Knowledge and background in biomolecule interaction and organic chemistry are desired.
Department:
Department of Mechanical Engineering (CU-Boulder)
Department of Pediatrics, Cardiology (UCHSC)
Faculty supervisor:
Wei Tan
Contact Information:
wtan@colorado.edu
If you are faculty
and would like to post a position, please
email us.
|
