Amber Bilak, Lyle Uyetake and Tin Tin Su. Dying cells protect survivors from radiation-induced cell death in Drosophila. PLoS Genetics, PLoS Genet. 2014 Mar 27;10(3):e1004220. PUBMED


Stefanie Stickel and Tin Tin Su. Oncogenic mutations produce similar phenotypes in Drosophila tissues of diverse origins. Bio Open,. 2014 Mar 15;3(3):201-9. PUBMED


Stefanie Stickel, Nathan Gomes and Tin Tin Su. The Role of Translational Regulation in Survival after Radiation Damage; an Opportunity for Proteomics Analysis. Proteomes 2014, 2(2), 272-290; doi:10.3390/proteomes2020272  ACCESS



van Bergeijk P, Heimiller J, Uyetake L, Su TT.  Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster. PLoS One. 2012;7(5):e36539. PMCID: PMC3362589 PUBMED


M. Gladstone*, B. Frederick*, D. Zheng, A. Edwards, P. Yoon, S. Stickel, T. DeLaney, D. C. Chan, D. Raben, T. T. Su. A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer. (*shared first authors) Disease Models and Mechanisms. 2012 May;5(3):342-50. PMCID: PMC3339828 PUBMED


M. Gladstone & T. T. Su. Radiation Responses and Resistance. International Review of Cell and Molecular Biology, Volume 299, 2012. In press.



A. Edwards*, Mara Gladstone (nee Stewart)*, P. Yoon, D. Raben, Barbara Frederick, T. T. Su, Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells, Disease Models and Mechanisms. (*shared first authors) 2011 Jul;4(4):496-503. Epub 2011 Apr 18. PUBMED


Smith MK, Trujillo C, Su TT. The benefits of using clickers in small-enrollment seminar-style biology courses. CBE Life Sci Educ. 2011 Spring;10(1):14-7. PUBMED


M. Gladstone & T. T. Su. Chemical genetics and drug screening in Drosophila cancer models. J. Genetics and Genomics, 2011 Oct 20;38(10):497-504. PUBMED


Su TT. Safeguarding genetic information in Drosophila. Chromosoma. 2011 Dec;120(6):547-55. doi: 10.1007/s00412-011-0342-9. Epub 2011 Sep 17. PUBMED


M. Gladstone & T. T. Su. Screening for radiation sensitizers of Drosophila checkpoint mutants. Methods Mol Biol., 2011;782:105-17. PUBMED



A. Wichmann, L. Uyetake and T. T. Su. E2F1 and E2F2 have opposite effects on radiation-induced p53-independent apoptosis in Drosophila, Dev Biol. 2010 346(1):80-9. PUBMED


T. T. Su. 2010. The effect of a DNA damaging agent on embryonic cell cycles of the cnidarian Hydractinia PLoS One. 2010 Jul 23;5(7):e11760. PUBMED


Su TT. Heterochromatin replication: better late than ever. Curr Biol. 2010 Dec 7;20(23):R1018-20. PUBMED




K. Garcia, J. Stumpff, T. Duncan, and T. T. Su. Tyrosines in the Kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spindle integrity. Current Biology 2009 19:1670-6. PDF


M. K. Smith, W. B. Wood, W. K. Adams, C. Wieman, J. K. Knight, N. Guild, T. T. Su. Why Peer Discussion Improves Student Performance on In-Class Concept Questions. Science, 323, 122 (2009) PDF/article        PDF/Supplement           Coverage in popular press


A. Bilak and T. T. Su. Regulation of Drosophila melanogaster pro-apoptotic gene hid. APOPTOSIS. 2009 Aug;14(8):943-9.  NIHMSID # 378751  PDF




Jaklevic B, Uyetake L, Wichmann A, Bilak A, English CN, Su TT. Modulation of ionizing radiation-induced apoptosis by bantam microRNA in Drosophila. Dev Biol. 2008 Aug 1;320(1):122-30. PubMed link                PDF


Yi X, Lemstra W, Vos MJ, Shang Y, Kampinga HH, Su TT, Sibon OC. A long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress. Cytometry A. 2008 Jul;73(7):637-42. PubMed


Garcia K, Su TT. Cell cycle regulation. Fly (Austin). 2008 May 23;2(3). PDF



J. LaRocque, Jaklevic B, Su TT, J. Sekelsky. Drosophila ATR in double-strand break repair. Genetics. 2007 Mar;175(3):1023-33. Epub 2006 Dec 28. PubMed            PDF

Garcia K, Wichmann, A., Su TT. Cell cycle regulation. Fly 1:2, 125-131; March/April 2007 PubMed


Kristin Garcia, Tod Duncan and T. T. Su. Analysis of the Cell Division Cycle in Drosophila. Methods, 2007 Feb;41(2):198-205. PubMed



Jaklevic B, Uyetake L, Lemstra W, Chang J, Leary W, Edwards A, Vidwans SJ, Sibon O, Su TT. Contribution of Growth and Cell Cycle Checkpoints to Radiation Survival in Drosophila. (2006) Genetics. 174(4):1963-72. Epub 2006 Oct 8. PubMed      PDF


Wichmann, A., Jaklevic, B. and T. T. Su, Ionizing Radiation induces caspase-dependent but Chk2 and p53-independent cell death in Drosophila melanogaster. (2006) PNAS 103(26):9952-7. PubMed                   PDF


T. T. Su. Cellular Responses to DNA Damage; One Signal, Multiple Choices. (2006) Annual Reviews in Genetics, 2006;40:187-208. PubMed



J. Stumpff, D. R. Kellogg, K. Krohne and T. T. Su. Drosophila Wee1 interacts with Members of <gamma>-TuRC and is required for proper mitotic spindle morphogenesis and positioning. (2005) Curr Bio, 15; 1525-34. PubMed    PDF/article         Supplement


A. Purdy, L. Uyetake, M. G. Cordeiro, T. T. Su. Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1). (2005) J. Cell Sci. 118: 3305-3315. PubMed      PDF


 de Vries HI, Uyetake L, Lemstra W, Brunsting JF, Su TT, Kampinga HH, Sibon OC. Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable. (2005) J Cell Sci.118:1833-42. PubMed                   PDF



Stumpff J, Duncan T, Homola E, Campbell SD, Su TT. Drosophila Wee1 kinase regulates Cdk1 and mitotic entry during embryogenesis. (2004) Curr Biol. 14:2143-8. PubMed   PDF/article    Supplement


B. Jaklevic and T. T. Su, Relative contribution of DNA repair, cell cycle checkpoints and cell death to survival after DNA damage in Drosophila larvae. (2004) Curr. Biol., Jan 6;14(1):23-32. Abstract  PDF


Jaklevic B, Purdy A, Su TT. Control of mitotic entry after DNA damage in Drosophila. Methods Mol Biol. 2004;280:245-56. PubMed


Purdy A, Su TT. Telomeres: not all breaks are equal. Curr Biol. 2004 Aug 10;14(15):R613-4. (Abstract)


Duncan T, Su TT. Embryogenesis: coordinating cell division with gastrulation. Curr Biol. 2004 Apr 20;14(8):R305-7. Review. No abstract available. (link)


Patrick H. O'Farrell, Jason Stumpff and Tin Tin Su. Embryonic cleavage cycles: how is a mouse like a fly? (2004) Curr. Biol. Jan 6;14(1):R35-45.  Abstract


Su, T.T., and Stumpff, J. (2004). Promiscuity rules? The dispensability of cyclin E and Cdk2. Sci STKE 2004, 224: pe11. Abstract




 B. De Felice, R. R. Wilson, P. Mondola, G. Matrone, S. Damiano, C. Garbi, L. Nezi, and T. T. Su. Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster. (2003) Biochemical and Biophysical Research Communications, 307:224-228. Abstract


 A. Lauren¨on, A. Purdy, J. Sekelsky, R. S. Hawley and T. T. Su. Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR (2003) Genetics, 164; 589-601. Abstract  PDF


B. Jaklevic and T. T. Su. Cell Turnover: Flexible Coupling Meets Needs of Development. (2003) Current Biology, 13:R805-7. Abstract



M. Garner, S. van Kreeveld and T. T. Su. mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos. (2001) Current Biology,11; 1595-1599. Abstract        PDF   Supplement



T. T. Su, D. H. Parry, B. Donahoe, C-T. Chien, P. H. O'Farrell, A. Purdy. Cell cycle roles for two 14-3-3 proteins during Drosophila development (2001) J. Cell Science, 114; 3445-3454. Abstract                                  PDF


Su, T. T. and Jaklevic, B. DNA damage leads to a Cyclin A-dependent delay in metaphase-anaphase transition in the Drosophila gastrula. Curr Biol 2001, 11:8-17 Abstract               PDF


Su, T. T. How, when and why cells get rid of Cyclin A. (2001) Current Biology, 11; R467-469. Abstract (missing from PubMed)


Vidwans, S. J. and Su, T. T. Cycling through development in Drosophila and other metazoa. Nature Cell. Biol. 2001. 3; E35-39. Abstract



Su, T. T. Walker, J, and Stumpff, J. Activating the DNA damage checkpoint in a developmental context. Curr Biol 2000 Feb 10;10(3):119-26. Abstract              PDF


Su, T. T. The regulation of cell growth and proliferation during organogenesis. In Vivo. 2000 Jan-Feb;14(1):141-8. Abstract


Su, T. T. and Vidwans S. J. DNA defects target the centrosome. Nat Cell Biol. 2000 Feb;2(2):E28-9. Abstract


Su, T. T. Immunoblotting of proteins from single Drosophila embryos. In 'Drosophila Protocols'. Edited by Sullivan, Ashburner and Hawley. 2000. Cold Spring Harbor Press.  Abstract (Book Chapter)


Tin Tin's papers, from her post-doc with Pat O' Farrell

Su, T. T. Campbell, S. D., and O'Farrell, P. H. Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events. (1999) Current Biology, 9:919-922. Abstract


Su, T. T. and O'Farrell, P. H., Size control: Cell proliferation does not equal growth. (1998) Current Biology, 8:R687-R689. Abstract(Review)


Su, T. T. Sprenger, F., DiGregorio, P., Campbell, S. D., and O'Farrell, P. H. Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation. (1998) Genes & Dev., 12: 1495-1503. Abstract


Su, T. T. Campbell, S. D., and O'Farrell, P. H. Cell cycle program in germ cells of the Drosophila embryo, Dev. Biol., (1998) 196; 160-170. Abstract


Su, T. T. and O'Farrell, P. H. Chromosome association of minichromosome maintenance proteins in Drosophila endoreplication cycles. (1998) J. Cell. Biol, 140; 451-460. Abstract


Su, T. T. and O'Farrell, P. H. Chromosome association of minichromosome maintenance proteins in Drosophila mitotic cycles. (1997) J. Cell. Biol. 139; 13-21. Abstract


Su, T. T., Yakubovich, N. and O'Farrell, P. H. Cloning of Drosophila MCM homologs and analysis of their requirement during embryogenesis. (1997) GENE, 192;283-289.  Abstract


Su., T. T. Feger, G. and O'Farrell, P. H. Drosophila MCM protein complexes. (1996) Mol. Biol. Cell. 7; 319-329 Abstract


Feger G, Vaessin H, Su TT, Wolff E, Jan LY, Jan YN. dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. (1995) EMBO J. 14:5387-98. Abstract


Su, T. T., Follette, P. J. and O'Farrell, P. H. Qualifying for the license to replicate. (1995) Cell 81; 825-828 Pub Med Link (Review-no abstract)


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