2012
M. Gladstone*, B. Frederick*,
D. Zheng, A. Edwards, P. Yoon, S. Stickel, T. DeLaney, D. C. Chan, D. Raben, T.
T. Su. A translation inhibitor identified in a Drosophila screen enhances the
effect of ionizing radiation and taxol in mammalian models of cancer. (*shared
first authors) In press.
2011
A. Edwards*, Mara Gladstone
(nee Stewart)*, P. Yoon, D. Raben, Barbara Frederick, T. T. Su, Combinatorial
effect of maytansinol and radiation in Drosophila and human cancer cells, Disease
Models and Mechanisms. (*shared first authors) 2011 Jul;4(4):496-503. Epub
2011 Apr 18. PUBMED
Smith MK, Trujillo C, Su TT.
The benefits of using clickers in small-enrollment seminar-style biology
courses. CBE Life Sci Educ. 2011 Spring;10(1):14-7. PUBMED
M. Gladstone & T. T. Su.
Chemical genetics and drug screening in Drosophila cancer models. J. Genetics
and Genomics, in press for 2011.
Su TT. Safeguarding genetic
information in Drosophila. Chromosoma. 2011 Sep 17. [Epub ahead of
print] PUBMED
M. Gladstone & T. T. Su.
Screening for radiation sensitizers of Drosophila checkpoint mutants. Methods
Mol Biol., 2011;782:105-17. PUBMED
2010
A. Wichmann, L. Uyetake and T.
T. Su. E2F1 and E2F2 have opposite effects on radiation-induced p53-independent
apoptosis in Drosophila, Dev Biol. 2010 346(1):80-9. PUBMED
T. T. Su. 2010. The effect of a
DNA damaging agent on embryonic cell cycles of the cnidarian Hydractinia
PLoS One. 2010 Jul 23;5(7):e11760. PUBMED
Su TT. Heterochromatin
replication: better late than ever. Curr Biol. 2010 Dec
7;20(23):R1018-20. PUBMED
2009
K. Garcia, J. Stumpff, T.
Duncan, and T. T. Su. Tyrosines in the Kinesin-5 head domain are necessary for
phosphorylation by Wee1 and for mitotic spindle integrity. Current Biology
2009 19:1670-6. PDF
M. K. Smith, W. B. Wood, W. K.
Adams, C. Wieman, J. K. Knight, N. Guild, T. T. Su. Why Peer Discussion
Improves Student Performance on In-Class Concept Questions. Science,
323, 122 (2009) PDF/article PDF/Supplement
Coverage
in popular press
A. Bilak and T. T. Su.
Regulation of Drosophila melanogaster pro-apoptotic gene hid.
APOPTOSIS. 2009 Aug;14(8):943-9. PDF
2008
Jaklevic B, Uyetake L, Wichmann
A, Bilak A, English CN, Su TT. Modulation of ionizing radiation-induced
apoptosis by bantam microRNA in Drosophila. Dev Biol. 2008 Aug
1;320(1):122-30. PubMed link
PDF
Yi X, Lemstra W, Vos MJ, Shang
Y, Kampinga HH, Su TT, Sibon OC. A long-term flow cytometry assay to analyze
the role of specific genes of Drosophila melanogaster S2 cells in surviving
genotoxic stress. Cytometry A. 2008 Jul;73(7):637-42. PubMed
Garcia K, Su TT. Cell cycle
regulation. Fly (Austin). 2008 May 23;2(3). PDF
2007
J. LaRocque, Jaklevic B, Su TT,
J. Sekelsky. Drosophila ATR in double-strand break repair. Genetics.
2007 Mar;175(3):1023-33. Epub 2006 Dec 28. PubMed
PDF
Garcia K, Wichmann, A., Su TT. Cell cycle regulation. Fly 1:2, 125-131;
March/April 2007 PubMed
Kristin Garcia, Tod Duncan and T. T. Su. Analysis of
the Cell Division Cycle in Drosophila. Methods, 2007 Feb;41(2):198-205. PubMed
2006
Jaklevic B, Uyetake L, Lemstra
W, Chang J, Leary W, Edwards A, Vidwans SJ, Sibon O, Su TT. Contribution of
Growth and Cell Cycle Checkpoints to Radiation Survival in Drosophila. (2006) Genetics.
174(4):1963-72. Epub 2006 Oct 8. PubMed PDF
Wichmann, A., Jaklevic, B. and
T. T. Su, Ionizing Radiation induces caspase-dependent but Chk2 and
p53-independent cell death in Drosophila melanogaster. (2006) PNAS
103(26):9952-7. PubMed
PDF
T. T. Su. Cellular Responses to DNA Damage; One
Signal, Multiple Choices. (2006) Annual Reviews in Genetics,
2006;40:187-208. PubMed
2005
J. Stumpff, D. R. Kellogg, K.
Krohne and T. T. Su. Drosophila Wee1 interacts with Members of
<gamma>-TuRC and is required for proper mitotic spindle morphogenesis and
positioning. (2005) Curr Bio, 15; 1525-34. PubMed PDF/article Supplement
A. Purdy, L. Uyetake, M. G.
Cordeiro, T. T. Su. Regulation of mitosis in response to damaged or
incompletely replicated DNA require different levels of Grapes (Drosophila
Chk1). (2005) J. Cell Sci. 118: 3305-3315. PubMed PDF
de Vries HI, Uyetake L,
Lemstra W, Brunsting JF, Su TT, Kampinga HH, Sibon OC. Grp/DChk1 is required
for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is
dispensable. (2005) J Cell Sci.118:1833-42. [PubMed]
PDF
2004
Stumpff J, Duncan T, Homola E,
Campbell SD, Su TT. Drosophila Wee1 kinase regulates Cdk1 and mitotic entry
during embryogenesis. (2004) Curr Biol. 14:2143-8. [PubMed]
PDF/article
Supplement
Jaklevic B, Purdy A, Su TT.
Control of mitotic entry after DNA damage in Drosophila. Methods Mol Biol.
2004;280:245-56. PubMed
Purdy A, Su TT. Telomeres: not all breaks are equal. Curr Biol. 2004 Aug
10;14(15):R613-4. (Abstract)
Duncan T, Su TT. Embryogenesis: coordinating cell division with gastrulation. Curr Biol.
2004 Apr 20;14(8):R305-7. Review. No abstract available. (link)
Patrick H. O'Farrell, Jason
Stumpff and Tin Tin Su. Embryonic cleavage cycles: how is a mouse like a fly?
(2004) Curr. Biol. Jan 6;14(1):R35-45. Abstract
Su, T.T., and Stumpff, J.
(2004). Promiscuity rules? The dispensability of cyclin E and Cdk2. Sci STKE
2004, 224: pe11. Abstract
2003
B. Jaklevic and T. T. Su,
Relative contribution of DNA repair, cell cycle checkpoints and cell death to
survival after DNA damage in Drosophila larvae. (2003) Curr. Biol., Jan
6;14(1):23-32. Abstract
PDF
B. De Felice, R. R.
Wilson, P. Mondola, G. Matrone, S. Damiano, C. Garbi, L. Nezi, and T. T. Su.
Characterization of DIP1, a novel nuclear protein in Drosophila melanogaster.
(2003) Biochemical and Biophysical Research Communications, 307:224-228.
Abstract
A. Lauren¨on, A. Purdy,
J. Sekelsky, R. S. Hawley and T. T. Su. Phenotypic analysis of
separation-of-function alleles of MEI-41, Drosophila ATM/ATR (2003) Genetics,
164; 589-601. Abstract
PDF
B. Jaklevic and T. T. Su. Cell
Turnover: Flexible Coupling Meets Needs of Development. (2003) Current
Biology, 13:R805-7. Abstract
2002
M. Garner, S. van Kreeveld and
T. T. Su. mei-41 and bub1 block mitosis at two distinct steps in response to
incomplete DNA replication in Drosophila embryos. (2001) Current Biology,11;
1595-1599. Abstract
PDF Supplement
2001
T. T. Su, D. H. Parry, B.
Donahoe, C-T. Chien, P. H. O'Farrell, A. Purdy. Cell cycle roles for two 14-3-3
proteins during Drosophila development (2001) J. Cell Science, 114;
3445-3454. Abstract
PDF
Su, T. T. and Jaklevic, B. DNA
damage leads to a Cyclin A-dependent delay in metaphase-anaphase transition in
the Drosophila gastrula. Curr Biol 2001, 11:8-17 Abstract
PDF
Su, T. T. How, when and why
cells get rid of Cyclin A. (2001) Current Biology, 11; R467-469. Abstract (missing from PubMed)
Vidwans, S. J. and Su, T. T.
Cycling through development in Drosophila and other metazoa. Nature Cell.
Biol. 2001. 3; E35-39. Abstract
2000
Su, T. T. Walker, J, and
Stumpff, J. Activating the DNA damage checkpoint in a developmental context. Curr
Biol 2000 Feb 10;10(3):119-26. Abstract
PDF
Su, T. T. The regulation of
cell growth and proliferation during organogenesis. In Vivo. 2000
Jan-Feb;14(1):141-8. Abstract
Su, T. T. and Vidwans S. J. DNA
defects target the centrosome. Nat Cell Biol. 2000 Feb;2(2):E28-9. Abstract
Su, T. T. Immunoblotting of
proteins from single Drosophila embryos. In 'Drosophila Protocols'. Edited by
Sullivan, Ashburner and Hawley. 2000. Cold Spring Harbor Press. Abstract (Book Chapter)
Tin Tin's papers, from her
post-doc with Pat O' Farrell
Su, T. T. Campbell, S. D., and
O'Farrell, P. H. Drosophila grapes/CHK1 mutants are defective in cyclin
proteolysis and coordination of mitotic events. (1999) Current Biology,
9:919-922. Abstract
Su, T. T. and O'Farrell, P. H.,
Size control: Cell proliferation does not equal growth. (1998) Current
Biology, 8:R687-R689. Abstract(Review)
Su, T. T. Sprenger, F.,
DiGregorio, P., Campbell, S. D., and O'Farrell, P. H. Exit from mitosis in
Drosophila syncytial embryos requires proteolysis and cyclin degradation, and
is associated with localized dephosphorylation. (1998) Genes & Dev.,
12: 1495-1503. Abstract
Su, T. T. Campbell, S. D., and
O'Farrell, P. H. Cell cycle program in germ cells of the Drosophila embryo, Dev.
Biol., (1998) 196; 160-170. Abstract
Su, T. T. and O'Farrell, P. H.
Chromosome association of minichromosome maintenance proteins in Drosophila
endoreplication cycles. (1998) J. Cell. Biol, 140; 451-460. Abstract
Su, T. T. and O'Farrell, P. H.
Chromosome association of minichromosome maintenance proteins in Drosophila
mitotic cycles. (1997) J. Cell. Biol. 139; 13-21. Abstract
Su, T. T., Yakubovich, N. and
O'Farrell, P. H. Cloning of Drosophila MCM homologs and analysis of their
requirement during embryogenesis. (1997) GENE, 192;283-289. Abstract
Su., T. T. Feger, G. and
O'Farrell, P. H. Drosophila MCM protein complexes. (1996) Mol. Biol. Cell.
7; 319-329 Abstract
Feger G, Vaessin H, Su TT,
Wolff E, Jan LY, Jan YN. dpa, a member of the MCM family, is required for
mitotic DNA replication but not endoreplication in Drosophila. (1995) EMBO J.
14:5387-98. Abstract
Su, T. T., Follette, P. J. and
O'Farrell, P. H. Qualifying for the license to replicate. (1995) Cell
81; 825-828 Pub Med Link
(Review-no abstract)
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