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Publications

2006

Beliakova-Bethell, N., Beckham, C., Giddings, Jr., T. H., Winey, M., Parker, R., and Sandmeyer, S.

Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components.
RNA 12 2006 94-101.     abstract

Araki, Y., Lau, C. K., Maekawa, H., Jaspersen, S. L., Giddings Jr., T. H., Schiebel, E., and Winey, M.

The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p.
Mol. Biol. Cell 2006 17:1959-1970.     abstract

Crasta, K., Huang, P., Morgan, G., Winey. M., and U. Surana

Activated Cdk1 promotes centrosome separation by preventing Cdh1-mediated proteolysis of microtubule associated proteins.
EMBO J. 2006 25:2551-2563.     abstract

Palframan, W. J., Meehl, J. B., Jaspersen, S. L., Winey, M. and Murray, A. W.

Anaphase inactivation of the spindle checkpoint.
Science 2006 313:680-684.     abstract

Jaspersen, S. L., Glazko, G., Giddings, Jr., T. H., Morgan, G., Mushegian, A., and Winey, M.

The Sad1-Unc84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.
J. Cell Biol. In press.

2005

Elde, N. C., Morgan, G., Winey, M., Sperling, L., Turkewitz, A. P.

Elucidation of clathrin-mediated endocytosis in Tetrahymena reveals an evolutionarily convergent recruitment of dynamin.
PLoS Genetics 1:514-526.     abstract

Yoder, T. J., McElwain, M. A., Francis, S. E., Bagley, J., Muller, E. G. D., Pak, B., O'Toole, E. T., Winey, M., and Davis, T. N.

Analysis of a spindle pole body mutant reveals defects in bi-orientation and illuminates spindle forces.
Mol. Biol. Cell. 2005 16:141-152.     abstract

Jones. M. H., Huneycutt, B. J., Pearson, C., Zhang, C., Morgan, G., Shokat, K., Bloom, K., and Winey, M.

Chemical genetics reveals a role for Mps1 kinase in kinetochore attachment during mitosis.
Curr. Biol. 2005 15:160-165.     abstract

Winey, M., Morgan, G. P., Straight, P. D., Giddings Jr., T. H., and Mastronarde, D. N.

Three-dimensional ultrastructure of Saccharomyces cerevisiae meiotic spindles.
Mol. Biol. Cell 2005 16:1178-1188.     abstract

Bowman, G. R., Elde, N. C., Morgan, G., Winey, M. and Turkewitz, A.

Core formation and docking/fusion competence are linked during secretory granule maturation in Tetrahymena.
Traffic 2005 6:303-323.     abstract

Stemm-Wolf, A. J., Morgan, G., Giddings Jr., T. Th., White, E. A., Marchione, R., McDonald, H. and Winey, M.

Basal body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family.
Mol. Biol. Cell 2005 16:3606-3619.     abstract

Elde, N. C., Morgan, G., Winey, M., Sperling, L., Turkewitz, A. P.

Elucidation of clathrin-mediated endocytosis in Tetrahymena reveals an evolutionarily convergent recruitment of dynamin.
PLoS Genetics 2005 Nov 4;1(5):e52 [Epub ahead of print].     abstract

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2004

Park, C. J., Song, S., Giddings Jr., T. H., Ro, H.-S., Sakchaisri, K., Park, J.-E., Seong, Y.-S., Winey, M., and Lee, K. S.

Requirement for Bbp1p in the proper mitotic functions of Cdc5p in S. cerevisiae. Mol.
Biol. Cell 2004 15:1711-1723.     abstract

Lau, C. K., Giddings, Jr., T. H. and Winey, M.

A Novel allele of Saccharomyces cerevisiae NDC1 reveals a potential role for the spindle pole body component Ndc1p in nuclear pore assembly.
Eucaryotic Cell 2004 3:447-458.     abstract

Jaspersen, S. L., Huneycutt, B. J., Giddings, Jr., T. H., Ahn, N. G., Resing, K. A. and Winey, M.

Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1.
Developmental Cell 2004 7:263-274.     abstract

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2003

Fisk HA, Mattison CP, Winey M.

Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression.
Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25): 14875-80.     abstract

Roberts, P., Moshitch-Moshkovitz, S., Kvam, E., O’Toole, E., Winey, M. and Goldfarb, D. S.

Piecemeal microautophagy of the nucleus in Saccharomyces cerevisiae.
Mol. Biol. Cell 2003 14:129-141     abstract

Chang, P., Giddings Jr., T. H., Winey, M., and Stearns, T.

Epsilon-tubulin is required for centriole duplication and microtubule organization.
Nat. Cell Biol. 2003 5:71-76.    abstract

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2002

Jaspersen, S. L., Giddings Jr., T. H., and Winey, M. 

Mps3p is a novel component of the yeast spindle pole body that interacts with the yeast centrin homolog, Cdc31p.
J. Cell Biol. 2002 159:945-956.     abstract

McBratney, S. and Winey, M.

Mutant membrane protein of the budding yeast spindle pole body is targeted to the endoplasmic reticulum degradation pathway.
Genetics. 2002 162:567-578.     abstract

Castillo, A. R., Meehl, J. B., Morgan, G., Schutz-Geschwender, A. and Winey, M.

The yeast protein kinase Mps1p is required for assembly of the integral spindle pole body component Spc42p.
J. Cell Biol. 2002 156:453-465.     abstract

Burns, C. G., Ohi, R., Mehta, S., O'Toole, E. T., Winey, M., Clark, T. A., Sugnet, C. W., Ares Jr., M., and Gould, K. L.

Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in S. cerevisiae.
Mol. Cell. Biol. 2002 22:801-815.   abstract

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2001

Jones, M. H., He, X., Giddings Jr., T. H. and Winey, M.

Yeast Dam1p has a role at the kinetochore in assembly of the mitotic spindle.
Proc. Natl. Acad. Sci. 2001 98:13675-13680.    abstract

Luca, F. C., Mody, M., Kurischko, C., Roof, D. M., Giddings Jr., T. H. and Winey, M.

Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit.
Mol. Cell. Biol. 2001 21:6972-6983.     abstract

Schaerer, F., Morgan, G., Winey, M. and Philippsen, P.

Cnm67p is a spacer protein of the Saccharomyces cerevisiae spindle pole body outer plaque.
Mol. Biol. Cell 2001 12:2519-2533.    abstract

Fisk HA, Winey M

The mouse Mps1p-like kinase regulates centrosome duplication.
Cell  2001 Jul 13;106(1):95-104     abstract

Friedman DB, Kern JW, Huneycutt BJ, Vinh DB, Crawford DK, Steiner E, Scheiltz D, Yates J 3rd, Resing KA, Ahn NG, Winey M, Davis TN

Yeast Mps1p phosphorylates the spindle pole component Spc110p in the N-terminal domain.
J Biol Chem 2001 May 25;276(21):17958-67    abstract

Giddings TH Jr, O'Toole ET, Morphew M, Mastronarde DN, McIntosh JR, Winey M

Using rapid freeze and freeze-substitution for the preparation of yeast cells for electron microscopy and three-dimensional analysis.
Methods Cell Biol 2001;67:27-42

Kerscher O, Hieter P, Winey M, Basrai MA

Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation.
Genetics 2001 Apr;157(4):1543-53    abstract

Haase SB, Winey M, Reed SI

Multi-step control of spindle pole body duplication by cyclin-dependent kinase.
Nat Cell Biol 2001 Jan;3(1):38-42     abstract

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2000

Chial HJ, Stemm-Wolf AJ, McBratney S, Winey M

Yeast Eap1p, an eIF4E-associated protein, has a separate function involving genetic stability.
Curr Biol 2000 Nov 30;10(23):1519-22 abstract

Daum JR, Gomez-Ospina N, Winey M, Burke DJ

The spindle checkpoint of Saccharomyces cerevisiae responds to separable microtubule-dependent events.
Curr Biol 2000 Nov 2;10(21):1375-8 abstract

Gomez-Ospina N, Morgan G, Giddings TH Jr, Kosova B, Hurt E, Winey M

Yeast nuclear pore complex assembly defects determined by nuclear envelope reconstruction.
J Struct Biol 2000 Oct;132(1):1-5 abstract

Straight PD, Giddings TH Jr, Winey M

Mps1p regulates meiotic spindle pole body duplication in addition to having novel roles during sporulation.
Mol Biol Cell 2000 Oct;11(10):3525-37 abstract

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1999

Jones MH, Bachant JB, Castillo AR, Giddings TH Jr, Winey M

Yeast dam1p is required to maintain spindle integrity during mitosis and interacts with the mps1p kinase.
Mol Biol Cell 1999 Jul;10(7):2377-91     abstract

Munoz-Centeno MC, McBratney S, Monterrosa A, Byers B, Mann C, Winey M 

Saccharomyces cerevisiae MPS2 encodes a membrane protein localized at the spindle pole body and the nuclear envelope.
Mol Biol Cell 1999 Jul;10(7):2393-406     abstract

O'Toole ET, Winey M, McIntosh JR

High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae
Mol Biol Cell 1999 Jun;10(6):2017-31    abstract

Chial HJ, Giddings TH, Siewert, E. A., Hoyt, M. A. and Winey, M

Altered dosage of the S. cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and polyploidy.
Proc Natl Acad Sci U S A 1999 Aug 31;96(18):10200-5     abstract

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1998

Chial HJ, Rout MP, Giddings TH, Winey M

Saccharomyces cerevisiae Ndc1p is a shared component of nuclear pore complexes and spindle pole bodies.
J Cell Biol 1998 Dec 28;143(7):1789-800    abstract

He X, Jones MH, Winey M, Sazer S

Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe.
J Cell Sci 1998 Jun;111 ( Pt 12):1635-47    abstract

Schutz AR, Winey M

New alleles of the yeast MPS1 gene reveal multiple requirements in spindle pole body duplication.
Mol Biol Cell 1998 Apr;9(4):759-74     abstract

Komarnitsky SI, Chiang YC, Luca FC, Chen J, Toyn JH, Winey M, Johnston LH, Denis CL

DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein.
Mol Cell Biol 1998 Apr;18(4):2100-7   abstract

Luca FC, Winey M

MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy.
Mol Biol Cell 1998 Jan;9(1):29-46    abstract

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1997

Winey M, Yarar D, Giddings TH Jr, Mastronarde DN

Nuclear pore complex number and distribution throughout the Saccharomyces cerevisiae cell cycle by three-dimensional reconstruction from electron micrographs of nuclear envelopes.
Mol Biol Cell 1997 Nov;8(11):2119-32    abstract

Schutz AR, Giddings TH Jr, Steiner E, Winey M

The yeast CDC37 gene interacts with MPS1 and is required for proper execution of spindle pole body duplication.
J Cell Biol 1997 Mar 10;136(5):969-82    abstract

O'Toole ET, Mastronarde DN, Giddings TH Jr, Winey M, Burke DJ, McIntosh JR

Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae.
Mol Biol Cell 1997 Jan;8(1):1-11    abstract

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1996

Hardwick KG, Weiss E, Luca FC, Winey M, Murray AW

Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.
Science 1996 Aug 16;273(5277):953-6     abstract

Weiss E, Winey M

The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint.
J Cell Biol 1996 Jan;132(1-2):111-23     abstract

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1995

Winey M, Mamay CL, O'Toole ET, Mastronarde DN, Giddings TH Jr, McDonald KL, McIntosh JR

Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle.
J Cell Biol 1995 Jun;129(6):1601-15     abstract

Lauze E, Stoelcker B, Luca FC, Weiss E, Schutz AR, Winey M

Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.
EMBO J 1995 Apr 18;14(8):1655-63    abstract

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1994

Vallen EA, Ho W, Winey M, Rose MD

Genetic interactions between CDC31 and KAR1, two genes required for duplication of the microtubule organizing center in Saccharomyces cerevisiae.
Genetics 1994 Jun;137(2):407-22    abstract

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1993

Winey M, Byers B

Assembly and functions of the spindle pole body in budding yeast.
Trends Genet 1993 Sep;9(9):300-4     abstract

Winey M, Hoyt MA, Chan C, Goetsch L, Botstein D, Byers B

NDC1: a nuclear periphery component required for yeast spindle pole body duplication.
J Cell Biol 1993 Aug;122(4):743-51     abstract

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1991

Winey M, Goetsch L, Baum P, and Byers B

MPS1 and MPS2: Novel yeast genes defining distinct steps of spindle pole body duplication.
J Cell Biol 1991; Aug;114(4):745-54.     abstract

Winey M, Baum P, Goetsch L, Byers B

Genetic determinants of spindle pole body duplication in budding yeast.
Cold Spring Harb Symp Quant Biol 1991;56:705-8

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