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Unit 1: Introduction and overview of animal development (3
weeks)
T 1/13 Class 1 - Introduction
to the course
Chp 1: 1-13; Chp 2: 25-31, 44-46 |
Please go to the following site and take this short survey on your attitudes about biology by Friday at midnight (3 free points!): attitude survey |
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R 1/15 Class 2 - Developmental control of gene expression
Chp 4: 86-92, Chp 5: 101-113, 116-119, 125-128, 130-132, 137 |
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T 1/20 Class 3 - Cell signaling
Chp 6: 139-142, 145-158, 160-161, 164-171, Chp 3: 71-74 (cadherins) |
Pre-lecture questions are in a different format this week, and are not due til Friday. See CU Learn to get started, or click directly on this link. |
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R 1/22 Class 4 - Cell behavior; fate, determination
and commitment
Chp 1: 10-15, Chp 3:53-62, 66-67
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T 1/27 Class 5 - Fertilization and cleavage
Chp 7: 175-180, 205-206--skim rest of chapter if you want; cleavage: Chp 8: 211-215, 243-246; Chp 10:291-295. |
Pre-lecture questions due 10 AM
Tuesday |
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R 1/29 Class 6 – Gastrulation and Neurulation Chp 10: 291-302; Chp 12: 373-380
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good web sites: xenbase
Review Session Friday 3:30-5 pm A120 |
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Unit 2: Induction and cell fate determination (3 weeks) T 2/3 Class 7- Axis formation in Drosophila and Xenopus Drosophila: Chp 3: 56-58, 63-64, Chp 9: 259, figure on 260; Chp 10: Xenopus: 291-295, 302-304, 306-310 |
Quiz 1 Monday 2/2 6-7 PM
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R 2/5 Class 8 - Early inductive events and induction of mesoderm (Xenopus) Chp 10: 305-312 |
Problem Set 3 due midnight Friday
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T 2/10 Class 9- The roles of the organizer Chp 10: 312-323 |
Pre-lecture questions due 10 AM
Tuesday
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R 2/12 Class 10- Induction of nervous system and nervous system patterning Chp 12: 380-391 |
Problem Set 4 due midnight Friday
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T 2/17 Class 11 - The neural crest Chp 13: 407-419, 422-424
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Note: please try to read the Artinger paper earlier rather than later so that you can be prepared for her guest lecture on Thursday |
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R 2/19 Class 12 - Guest : Kristin Artinger |
guidance for reading neural crest paper Problem Set 5 due midnight Friday Review Session Friday 2:30-4 pm A120 |
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| Unit 3: Developmental Genetics (3 weeks)
T 2/24 Class 13 - Introduction to developmental genetics (techniques and concepts)
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Quiz 2 Monday 2/23 6-7 PM
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R 2/26 Class 14 - Applications of developmental
genetics (C. elegans)
Chp 8: 243-251
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Problem Set 6 due midnight Friday
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T 3/3 Class 15 Genetic analysis of C. elegans post-embryonic development sidelights and speculations, pp 162-163
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Pre-lecture questions due in class: Network probelm |
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R 3/5 Class 16- Application of developmental genetics to Drosophila early embryogenesis
Chp 9: 253-278 |
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T 3/10 Class 17- Drosophila Segmentation and Vertebrate segmentation Chp 9: 278-283; Chp 14: 443-450 |
Pre-lecture questions due 10 AM
Tuesday
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R 3/12 Class 18 –Segment identity and Hox
genes
Chp 9: 283-287; Chp 11: 361-364 |
Problem Set 8 due midnight Friday
answers
Review Session Friday 2:30-4 pm A120
quiz3review
answers to practice epistasis qs |
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Unit 4: Patterning (limb and brain)
T 3/17 Class
19- Patterning of the limb Chp 16 |
Quiz 3 Monday 3/16 6-7 PM |
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R 3/19 Class 20- Patterning of the limb, continued: Guest Dr. Lee Niswander |
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Week of 3/23 - no class, Spring Break
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T 3/31 Class 21 - Finishing patterning in the limb
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Pre-lecture questions due 10 AM
Tuesday
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R 4/2 Class 22 - Neuronal migration and axon guidance
Chp 13: 424-440
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T 4/7 Class 23 – Neuronal plasticity
Chp 13: 424-440
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Pre-lecture questions due 10 AM Tuesday |
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R 4/9 Class 24 --Mouse transgenics: techniques and applications for studying the nervous system Chp 4: 92-95; Chp 11: 348-357
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Problem Set 11 due midnight Friday Review Session Friday 2:30-4 pm A1B20 (downstairs from usual classroom) |
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Unit 5 Sex determination and Stem cells T 4/14 Class 25 – Sex determination
Chp 17; p. 129
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Quiz 4 Monday 4/13 6-7 pm |
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R 4/16 Class 26 - Dosage compensation
Chp 5: 119-124; 550
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T 4/21 Class 27 -- Imprinting
Chp 5: 117-118, sidelights and speculations: p. 207
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Pre-lecture questions due 10 AM
Tuesday
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R 4/23 Class 28-
Stem cells
Chp 4: 82-86 ; Chp 15: 489-493 |
Problem Set 13 due midnight Friday
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T 4/28Class 29 – Stem cells in muscle development: Guest Dr. Brad Olwin |
Pre-lecture questions due 10 AM
Tuesday
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R 4/30 Class 30 - Last day of class - Review
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Review Session for Final: Sunday May 3 4:30 PM |
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Cumulative Final Exam Tuesday May 5 4:30-7 pm, A120
MCDB
The final exam will include 2 sections--Quiz 5 (classes 25-29) and the cumulative final |
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