Updated 4/19/2012 4:15 PM
ASEN 5016
SPACE
LIFE SCIENCES
Spring 2012
Tues/Thurs 2-3:15 pm
ECCS 1B12
Distance Learning access via
CAETE
Instructor: Dr.
David Klaus
telephone: (303) 492-3525
email:
This course is primarily intended to familiarize engineering students with factors affecting living organisms (ranging from single cells to humans) in the reduced-gravity environment of space flight, including lunar and Martian surface conditions. Unique insight will be gained regarding engineering design requirements for spacecraft habitats, life support systems and spacesuits, as well as space biology payloads. Life support fundamentals, as they relate to basic human survival requirements, are covered initially. Next, the lectures turn to more detailed descriptions of the physiological adaptations that occur to people in space, with pertinent background information presented for each topic. Corresponding biomedical countermeasures needed to maintain crew health for long duration missions will also be discussed, including future Moon and Mars exploration. Finally, the underlying biophysical mechanisms affected by gravity, along with experiment design criteria, will be addressed. Current events within NASA’s future exploration mission programs and the emerging commercial human space flight sector are reflected throughout the lecture topics.
To further elaborate on the lecture material presented in class, a series of integrated homework tasks provides a practical introduction to the process of journal article publishing and research proposal writing, including the peer review process used for each. The assignment begins with writing a short journal article on a relevant topic of your choice, participating as a peer reviewer for the editor, revising your draft per the review comments you receive back, and submitting a final manuscript. From this background, you will subsequently prepare a research grant proposal that builds on your selected topic (along with a CV and budget) and culminates in a mock review panel. This end-to-end flow closely mimics the standard practice in the scientific community and is a valuable generic process to experience regardless of your specific research interests.
BULLETIN BOARD
3/15/12
Take Home Quiz assigned in today’s lecture is due 3/20.
For CAETE students, the THQ is due 5 days after viewing the
Radiation lecture, so let me know when you get to that point.
All lectures that will be covered on Exam 2 and the HW1
Revise and Resubmit instructions are posted now.
HW4 Proposal Review Evaluation metrics are also online as a
heads up on how the proposals will be scored.
HW3 assignment moved to Tuesday 3/6
New deliverable added to HW1 flow… HW1 ‘Working Title’ of review article due – 2/21
OFFICE HOURS: TBD
LECTURE TOPICS – order and topics subject to slight revision
Course Overview & Historical Perspectives on Human Space Flight
Relevant Space Flight Environmental Parameters
Human Spacecraft Life Support Requirements and Considerations
Respiration and the Oxygen Cascade
Nutrition –
Ch. 8 & Temperature Regulation
Gravity Dependent Physical Processes
Wrap up / Exam Review
Exam 1 – 2/16/2011
Miscellaneous Human Physiological Responses to Space Flight
Physiology of Extravehicular Activity (EVA) – Ch. 5 (Guest Lecturer Joe Tanner)
Neuro-Sensory System – Ch. 6 (balance) & Ch. 9 (motion sickness)
Hormonal Regulation & Immunological Response
Cardiovascular System – Ch. 7 (Guest Lecturer Prof Stodieck)
Wrap up / Exam Review
Exam 2 – 3/22/2011
-- Spring Break Week 3/26-30
Space Biology Experiment Design & Proposal Writing
Summary of Current Biomedical Countermeasures – Ch. 11 & 12 (partial)
Plant and Animal Research in Space
Microbial Responses & Related Crew Health Issues
Psycho-Sociological Aspects – Ch. 2
Operational Space Medicine – Ch. 12 (partial)
Astrobiology
Wrap up / Mock panel prep
Mock Review Panel – Final Exam Period, Saturday May 5, 1:30-4pm
GRADING 20%
- Exam 1
20% - Exam 2
10% - Take Home Quizzes
20% -
Homework 1, Review Article – grade based on final ‘revised and resubmitted’ version following
peer review
5% - Homework 2, Journal Peer Review – your participation as a
reviewer
20% -
Homework 3, Research Proposal – grade based on proposal submittal with consideration of reviewer
comments
5% - Homework 4, Proposal Peer Review – your participation as a reviewer and
in the ‘Mock Panel Meeting’
HW1 Review Article (Instructions
for Authors) assigned – 1/24
HW1 Topic Selection due – 2/2
HW1 Bibliography List / Article Synopsis due – 2/14
HW1 ‘Working Title’ of review article due – 2/21
HW1 Manuscript First Draft (one hardcopy and
electronic file) with Cover Letter (in email body only) due – 2/28
extended to 3/1
HW2 Journal Peer Review Process (Evaluation
Metrics) Assigned (Reviewer
Instructions) – 3/1 delayed to 3/2
HW3 Research RFP Released (Submission
Guidelines) – 3/6
HW2 Reviewer Comments / Score Sheets due – 3/8
HW3 Research Proposal NOI due – 3/13
HW2 Reviewer Comments / Interim Score Returned to
Authors – 3/15
HW3 Proposal Budget (budget
template) and CV Discussion
– 4/3
HW1 Final Manuscript (Revise
& Resubmit Instructions) due with Cover Letter (modified sample from actual review process) – 4/5
HW3 Research Proposal due (hardcopy and electronic) – 4/19
HW4 Proposal Review Process (Evaluation Metrics) assigned – 4/24
HW4 Reviewer Score Sheets due (hardcopy only for local students, e-copy
for CAETE ok) – 5/1
HW4 Proposal Review Panel assigned – 5/1 (NOTE: for this exercise, CAETE
students are on the same schedule as the local class)
HW4 Mock Review Panel Meeting – Final Exam
Period (Saturday 5/5, 1:30-4 pm)
TEXT “Space
Physiology” by Buckey,
Suggested optional, ancillary references for additional information on this field of study
“Textbook of Medical Physiology” 12th ed. Guyton and Hall, 2010
“Fundamentals of Space Medicine” Clement, Kluwer Academic Press, 2003
“Fundamentals of Aerospace Medicine,” 4th ed., Dehart and Davis, 2008
“Going Higher – Oxygen, Man and
Mountains” 4th ed.,
“Space Physiology and Medicine,” 3rd ed., Nicogossian, Huntoon and Pool, 1994 (out of print, difficult to find)
“Bioastronautics Data Book,”2nd ed., Parker and West (eds.), NASA SP-3006, 1973 (1st ed., 1964, both are out of print, difficult to find)
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